A5101812245- Animal Virus Infections Studies
- Viral gastroenteritis research and epidemiology
- Veterinary medicine and infectious diseases
- Virus-based gene therapy research
- Hepatitis Viruses Studies and Epidemiology
- Microbial infections and disease research
- Helicobacter pylori-related gastroenterology studies
- Herpesvirus Infections and Treatments
- Vibrio bacteria research studies
- Trace Elements in Health
- Antibiotics Pharmacokinetics and Efficacy
- Immune Response and Inflammation
- Heavy Metal Exposure and Toxicity
- Viral Infections and Immunology Research
- SARS-CoV-2 and COVID-19 Research
- Mycobacterium research and diagnosis
- Peripheral Neuropathies and Disorders
- Plant and Fungal Interactions Research
- Plant Virus Research Studies
- Animal Disease Management and Epidemiology
- Advanced biosensing and bioanalysis techniques
- Chromium effects and bioremediation
- Phytochemistry and Bioactivity Studies
- Gastric Cancer Management and Outcomes
- Galectins and Cancer Biology
National Institute for Communicable Disease Control and Prevention
2010-2025
Shandong Agricultural University
2020-2023
Shandong Entry-Exit Inspection and Quarantine Bureau
2022
Abstract Background Porcine circovirus type 2 (PCV2) is one of the crucial swine viral pathogens, caused porcine associated diseases (PCVAD). Shandong province most important pork producing areas and bears a considerable economic loss due to PCVAD. However, there limited information on epidemiology coinfection rate PCV2 with other critical in this area, such as reproductive respiratory syndrome virus (PRRSV), classical fever (CSFV), Pseudorabies (PRV), epidemic diarrhea (PEDV). Results...
The abuse of antibiotics has led to widespread resistance Helicobacter pylori (H. pylori) in the population. There is an urgent need establish a method detect multiple antibiotic rapidly. This study aimed construct novel strategy for high-throughput detection H. pylori's varying using multiplex PCR-mass spectrometry mini-sequencing (mPCR-MS mini-sequencing) technology. detected six eight mutated sites (23S rRNA-2143; pbp1A-1667, 1684, 1240; gyrA-261, 271, 573; and 16S rRNA-928) four genes...
In recent years, the poultry industry had been markedly affected by adenoviral diseases such as hydropericardium syndrome and inclusion body hepatitis caused fowl adenovirus (FAdV), which have become increasingly prevalent in China. Shandong Province, China, is an important area for breeding where various complex diverse FAdV serotypes were isolated. However, dominant strains their pathogenic characteristics are not yet reported. Therefore, a pathogenicity epidemiological survey of was...
Pseudorabies, also known as Aujeszky's disease, is caused by the pseudorabies virus (PRV) and has been recognized a critical disease affecting pig industry wide range of animals around world, resulting in great economic losses each year. Shandong province, one most vital food animal-breeding regions China, very dense population, within which infections were detected recent years. The data, however, on PRV epidemiology coinfection rates with other major swine diseases sparse.This study aimed...
Florfenicol (FLO) is one of the most popular antibacterial drugs used in veterinary clinics and aquaculture. The drug was found to decrease hatchability eggs laid by treated hens research work. However, pathological changes developing embryos their cardiovascular system mechanism underlying FLO-induced embryonic death remain unclear. In present study, fertilized with a therapeutic dose FLO were collected incubated. Results showed that exposure repressed development induced early death. As...
Responsible for the acute infectious disease porcine epidemic diarrhea (PED), PED virus (PEDV) induces severe and high mortality in infected piglets thus severely harms productivity economic efficiency of pig farms. In our study, we aimed to investigate analyze recent status incidence pattern PEDV infection some areas Shandong Province, China. We collected 176 clinical samples from farms different regions Province during 2019-2021. PEDV, TGEV, PORV were detected using RT-PCR. The full-length...
Background Helicobacter pylori (H. pylori) has infected approximately 4.4 billion individuals worldwide. The known virulence genes and the existing H. typing methods have not been shown to a recognized correlation with its infectivity. aim of this study was elucidate relationships among important genes, coccoid transformation, cytotoxicity isolated from different clinical diseases provide guidance for development new pylori.
Avian hepatitis E virus (HEV) is the pathogenic agent of big liver and spleen disease (BLS) hepatitis-splenomegaly syndrome (HSS) in chickens, which have caused economic losses to poultry industry China. In this study, 18 samples BLS chickens were collected reveal molecular epidemiological characteristics avian HEV province Shandong, China.Gross microscopic lesions clinical observed; then, virology detection genetic analysis performed. The results showed that there was significant swelling...
Background Blackened intestines in slaughtered pigs have been commonly observed China recent years. However, no cause has reported. Objectives We attempted to determine whether the blackening of pig intestine was related an excess copper (Cu) their feed. Methods In this study, we and collected porcine small- large-scale slaughterhouses Shandong province from May October 2018. Twelve types metal ions were detected black intestinal samples. Results The Cu level samples mostly higher than...
Chicken infectious anemia (CIA) is a vertical transmission chicken disease caused by the virus (CAV). The can induce stunting and immunosuppression in chicks infecting bone marrow-derived stem cells, causing huge economic losses for poultry industry. To determine prevalence of CIA Shandong Province, China, 854 suspected samples were collected analyzed 13 cities from 2020 to 2022. PCR results showed that total 115 CAV isolated. CAV-positive rates 17.21% (26/151) 2020, 12.23% (35/286) 2021,...
To investigate the prevalence of avian hepatitis E virus (HEV) in chickens and gather evidence viral vertical transmission, we collected 288 cloacal swabs yolks samples from 12 farms with clinically healthy 4 different areas Tai'an City, Shandong Province, China (i.e., Daiyue District, Xintai Feicheng Ningyang County). We also 240 2 breeder (from each which 30 chicks, dead embryos, live hatching eggs were taken). PCR detection revealed that positive rates 6.25% (18/288) 4.51% (13/288),...
Abstract Background: Avian hepatitis E virus (HEV) is the pathogenic agent of big liver and spleen disease (BLS) hepatitis-splenomegaly syndrome (HS) in chickens, which has caused economic losses to poultry industry China. Eighteen samples BLS chickens were collected this study understand molecular epidemiology characteristics avian HEV Shandong province, Results: Gross microscopic lesions clinical observed, then virology detection genetic analysis performed. The results showed that there...