A5087261701- Retinal Diseases and Treatments
- Retinal Development and Disorders
- Corneal surgery and disorders
- Diabetes and associated disorders
- Neurogenetic and Muscular Disorders Research
- Amyotrophic Lateral Sclerosis Research
- Salivary Gland Disorders and Functions
- Photoreceptor and optogenetics research
- Glaucoma and retinal disorders
- Folate and B Vitamins Research
- Retinopathy of Prematurity Studies
- Ocular Surface and Contact Lens
- Alcoholism and Thiamine Deficiency
- Neuroscience and Neuropharmacology Research
- Lysosomal Storage Disorders Research
- Neurological diseases and metabolism
University of California, Davis
2023-2025
Veterinary Medical Teaching Hospital
2024
Auburn University
2020-2021
Carolina Veterinary Specialists
2021
Florida College
2020
University of Florida
2020
A clinical need exists for more effective intravitreal (IVT) drug delivery systems (DDS). This study tested the hypothesis that a novel biodegradable, injectable microsphere-hydrogel system loaded with aflibercept (aflibercept-DDS) would exhibit long-term safety and biocompatibility in non-human primate (NHP) model. We generated aflibercept-loaded poly (lactic-co-glycolic acid) microparticles modified double emulsion technique then embedded them into thermo-responsive (ethylene...
Abstract Congenital stationary night blindness (CSNB) is an ocular disorder characterized by nyctalopia. An autosomal recessive missense mutation in glutamate metabotropic receptor 6 ( GRM6 c.533C>T, p.(Thr178Met)), called CSNB2 , was previously identified one Tennessee Walking Horse and predicted to reduce binding affinity of the neurotransmitter glutamate, impacting retinal rod ON‐bipolar cell signaling pathway. Thus, first aim identify allele frequency (AF) breeds with reported cases...
Abstract Objective To report the long‐term (>1 year) outcome of MicroPulse transscleral diode cyclophotocoagulation (MP‐TSCP) in dogs. Animals Studied Client owned dogs that underwent MP‐TSCP at a veterinary referral center. Procedure Retrospective study 19 treated with MP‐TSCP. Dogs were evaluated median follow‐up time 30.5 months postoperatively. Reported outcomes intraocular pressure (IOP), retention or loss vision, number medications, and additional procedures performed. Variables...
Sjogren's disease, well-described in people, is rarely identified veterinary species. In disease one of the most common systemic autoimmune disorders with an incidence 0.5% female population. The hallmark histopathologic finding primary lymphomononuclear cell infiltrates aggregating as periductal infiltrate salivary glands. Sjogren's-like has been reported a domestic shorthair cat and golden retriever dog. However, both lacked positive antinuclear antibody (ANA) titers dog showed no clinical...