A5062338777- Cellular Mechanics and Interactions
- Skin and Cellular Biology Research
- Microtubule and mitosis dynamics
- Cell Adhesion Molecules Research
- Angiogenesis and VEGF in Cancer
- RNA regulation and disease
- Sperm and Testicular Function
- Mitochondrial Function and Pathology
- Hormonal and reproductive studies
- Erythrocyte Function and Pathophysiology
- TGF-β signaling in diseases
- Cell Image Analysis Techniques
- RNA Research and Splicing
- Neurological diseases and metabolism
- Biomedical Research and Pathophysiology
- Nanoparticles: synthesis and applications
- Ubiquitin and proteasome pathways
- Nanoparticle-Based Drug Delivery
- Bioinformatics and Genomic Networks
- Advanced Fluorescence Microscopy Techniques
- Graphene and Nanomaterials Applications
- Reproductive Biology and Fertility
- Bioactive Compounds and Antitumor Agents
- Organic Chemistry Cycloaddition Reactions
- Blood properties and coagulation
Lomonosov Moscow State University
2017-2024
Moscow State University
2014-2024
Institute of Protein Research
2024
Intermediate filaments (IFs), being traditionally the least studied component of cytoskeleton, have begun to receive more attention in recent years. IFs are found different cell types and specific them. Accumulated data shifted paradigm about role as structures that merely provide mechanical strength cell. In addition this role, been shown participate maintaining shape strengthening adhesion. The also obtained point out a number other biological processes, including organization microtubules...
Theranostics application of superparamagnetic nanoparticles based on magnetite and maghemite is impeded by their toxicity. The use additional protective shells significantly reduced the magnetic properties nanoparticles. Therefore, iron carbides pure coated with multiple layers onion-like carbon sheath seem to be optimal for biomedicine. Fluorescent markers associated provide reliable means multimodal visualization. Here, biocompatibility graphite-like shell labeled Alexa 647 fluorescent...
The study objective is to perform clinical laboratory evaluation of the effectiveness Prostatilen ® AC and Arginine-zinc in treatment patients with sperm pathology concomitant varicocele chronic nonbacterial prostatitis. Materials methods. included 60 between 23 46 years age. first group 30 (15 15 prostatitis) who received AC. second Arginine-zinc. Therapy duration was 20 days. Standard examination, spermiologic examination as well measurement antisperm antibodies, DNA fragmentation,...
Steroid dimers of natural and synthetic origin possess an unusual complex molecular architecture that may lead to the realization peculiar effects in biological systems, particular different cancer cell lines. In present work, diastereoselective ring-opening mono- polyoxiranes, containing a cyclooctane core, by azide-anion was performed yield series azidoalcohols with types symmetry. The products were involved copper-catalyzed azyde-alkyne cycloaddition (CuAAC) reaction ethinylestradiol...
Abstract Intermediate filaments (IFs) represented by a diverse range of proteins, are one the three main cytoskeleton components in different types animal cells. IFs provide mechanical strength to cells and help position nucleus organelles cell. Desmin is an IF protein typical muscle cells, while vimentin, which has similar structure, expressed many mesenchymal Both proteins synthesized during myogenesis regeneration damaged tissue form mixed network. desmin vimentin regulate mitochondrial...
The aim of the study was to evaluate clinical and laboratory effectiveness peptide bioregulator Samprost® in correction pathospermia men with secretory type infertility caused by chronic nonbacterial prostatitis (CNP) varicocele postoperative period. Materials methods . multicenter included 30 patients between 23 51 years age: 15 CNP (1st group) due period (2nd group). Patients all groups received for 20 days form intramuscular injections 5 mg daily. design provided a traditional clinical,...
Actin cytoskeleton is an essential component of living cells and plays a decisive role in many cellular processes. In mammals, β- γ-actin are cytoplasmic actin isoforms non-muscle cells. Despite minor differences the amino acid sequence, localize different cell structures perform functions. While β-actin involved intracellular processes including contraction, responsible for mobility promotes tumor transformation. Numerous studies demonstrate that spatially separated cytoplasm fibroblasts...