A5057841655- Ginseng Biological Effects and Applications
- Metabolomics and Mass Spectrometry Studies
- Gut microbiota and health
- Phytochemicals and Antioxidant Activities
- Pharmacological Effects of Natural Compounds
- Traditional Chinese Medicine Analysis
- Food Quality and Safety Studies
- Inflammatory Bowel Disease
- Tryptophan and brain disorders
- Lipoproteins and Cardiovascular Health
- Plant Physiology and Cultivation Studies
- Genomics, phytochemicals, and oxidative stress
- Plant-derived Lignans Synthesis and Bioactivity
- Healthcare and Venom Research
- Acupuncture Treatment Research Studies
- Natural product bioactivities and synthesis
- Ziziphus Jujuba Studies and Applications
- Postharvest Quality and Shelf Life Management
- Computational Drug Discovery Methods
- Essential Oils and Antimicrobial Activity
- Phytoestrogen effects and research
- Bipolar Disorder and Treatment
- Traditional Chinese Medicine Studies
- Mast cells and histamine
- Biological and pharmacological studies of plants
Columbia University Irving Medical Center
2024
China Pharmaceutical University
2022-2024
Changchun University of Chinese Medicine
2017-2024
Shandong Provincial QianFoShan Hospital
2024
Xinjiang Academy of Agricultural and Reclamation Science
2022
Animal Science Research Institute
2022
Shandong University
2021
Affiliated Hospital of Jiangxi University of Traditional Chinese Medicine
2021
Zhejiang University of Technology
2021
Heilongjiang University of Chinese Medicine
2018
Inflammatory bowel disease (IBD) is associated with acute and chronic inflammation of the gastrointestinal tract has emerged to be a global disease. Spermidine, natural polyamine, plays critical role in maintaining cellular homeostasis. Herein, we investigated impact mechanism spermidine on both dextran sulfate sodium (DSS)- 2,4,6-trinitrobenzenesulfonic acid solution (TNBS)-induced colitis mice. We found that exerted protective effects against colitis, evidenced by reduced activity index...
Atractylodes macrocephala Koidz. is one of the most frequently used traditional Chinese medicines for treatment ulcerative colitis (UC). The beneficial effect polysaccharide from (PAMK) on UC has been reported, while underlying mechanism and target remain unclear. In this study, we systematically investigated therapeutic PAMK in based a mouse model dextran sodium sulfate (DSS)-induced colitis. (100 mg/kg, 200 mg/kg 400 mg/kg) significantly ameliorated DSS-induced colitis, manifested as...
The structural conversions in ginsenosides induced by steaming or heating acidic condition could improve red ginseng bioactivities significantly. In this paper, the chemical transformations of American from fresh Panax quinquefolium L. under were investigated, and possible mechanisms discussed. A method with reversed-phase high-performance liquid chromatography coupled linear ion trap mass spectrometry (HPLC-MSn)-equipped electrospray ionization source was developed for analysis quantitation...
Black chokeberry is a deciduous perennial shrub. As kind of berried fruit plants, its sweet and sour with slightly astringent. It not only rich in nutrients but also has high health functions. The fruits black are proanthocyanidins, anthocyanins other polyphenolic bioactive components. Considering the instability components, extraction, purification, determination could influence recovery content evaluation significantly. This paper reviewed compared research on main chemical components...
Dried and red ginseng are well-known types of processed widely used as healthy food. The dried quality may vary with the storage period raw ginseng. Therefore, herein, effect fresh on was evaluated through multicomponent quantification statistical analysis.A method based ultrahigh performance liquid chromatography coupled to triple quadrupole mass spectrometry in multiple-reaction monitoring mode (UPLC-MRM-MS) developed for quantitation ginsenosides oligosaccharides Principal component...
Bovine parainfluenza virus 3 (BPIV3) is one of several viruses that contribute to bovine respiratory disease complex (BRDC). During this study, isolation BPIV3 was attempted from 20 PCR-positive swabs by Madin-Darby Kidney (MDBK) cells. Nine samples showed obvious cytopathic lesions identified as reverse-transcription polymerase chain reaction amplification and sequencing. The genomes isolates XJ21032-1 XJ20055-3 were sequenced using Illumina sequencing technology determined have lengths...
Ginseng is the main Chinese herbal medicine for tonifying Qi and invigorating spleen. It has been used to treat spleen-qi deficiency with good protective effects thousands of years, however, its biological mechanism not fully elucidated. This study aims explore ginseng in treatment by using a comprehensive method combining metabolomics network pharmacological analysis. Gas chromatography-mass spectroscopy was applied investigating changes urine metabolites rats after ginseng. Metabolomics...
Ginsenosides in Panax quinquefolium L. were determined using developed ultra-performance liquid chromatography coupled to high resolution mass spectrometry (UPLC-HRMS) method with electrospray ionization and orbitrap MS analyzer negative mode. Optimal UPLC separation was achieved a mixture of acetonitrile water 0.1% formic acid as the mobile phase linear gradient elution. The parameters optimized for reliable detection enhanced selectivity sensitivity, improved identification quantification...
The digestive tract microorganisms play a very important role in the host's nutrient intake, environmental suitability, and affect physiological mechanism. Previous studies showed that different seasons, mammalian gut microbes would be different. However, most of them are concentrated wild animals. It remains unclear how seasonal change affects Chinese merino fine-wool Sheep. Therefore, this experiment, we continuously collected blood feces samples 50 sheep measured indicators blood, passed...
The basic properties of herbal medicines are cold, hot, warm, and cool. differentiation these is important for the diagnosis treatment diseases. Ginseng American ginseng possess opposite warm cool, respectively. At present, mechanisms influence steaming leading to differences in their not clear require further investigation. Therefore, nontargeted metabonomics based on liquid chromatography-mass spectrometry was applied investigate effects ginseng, variants changes endogenous metabolites rat...
A method with ultrahigh performance liquid chromatography Quadrupole-Orbitrap tandem mass spectrometry (UHPLC-Q-Orbitrap-MS/MS) was applied for the quality evaluation of different processing and drying American ginseng, including natural (ND), steam (SD), vacuum freeze-drying (VFD). total 51 saponins were successfully identified in three processed products. Three ginseng products well-differentiated orthogonal partial least-squares discriminant analysis (OPLS-DA). The S-plot also marker...
To explore a green and efficient extraction technology for the of active ingredients Asarum, deep eutectic solvent combined with ultrasonic was applied to compare efficiency 10 kinds solvents, taking rate methyl eugenol asarinin as indices. Single-factor experiments were adopted investigate influence molar ratio, liquid-to-solid eddy time, temperature on asarinin. Based single-factor experiments, surface response methodology used optimize process conditions. The results showed that optimum...
Schisandra chinensis fruit is a famous tonic traditional Chinese medicine and healthy food. The chemical components of dried fruits may vary with the initial processing methods fresh fruits. Therefore, in this study, influence drying was evaluated based on targeted metabolomics analysis. ultrahigh performance liquid chromatography-triple quadrupole mass spectrometry (UPLC-QQQ-MS) applied determination multicomponent including lignans, organic acids, oligosaccharides. were processed by...
Ginseng has been used to treat Qi-deficiency syndrome up now, while the therapeutic mechanism is still unclear. In order explore of ginseng in treatment constitution, untargeted metabonomics with blood was studied based on rapid resolution high performance liquid chromatography-quadrupole time-of-flight mass spectrometry(RRLC-Q-TOF-MS). results, 13 potential biomarkers were found and identified, which mainly involved body's antioxidant immune functions energy, glycerol, fatty acid, sugar...
Recent studies have highlighted the beneficial effect of resolvin D1 (RvD1), a DHA-derived specialized pro-resolving mediator, on metabolic dysfunction-associated steatohepatitis (MASH), but underlying mechanisms are not well understood. Our study aims to determine mechanism by which RvD1 protects against MASH progression.
Schisandra chinensis is a functional fruit with tonic effect and was widely used by traditional Chinese medicine for treatment health care. The quality of may vary different storage condition. In this study, the influence ambient temperature, humidity, packaging materials period on fruits were investigated. contents main active components lignans organic acids simultaneously determined ultra-performance liquid chromatography coupled to quadrupole electrostatic field orbitrap high resolution...