A5102738752- Ginseng Biological Effects and Applications
- Analytical chemistry methods development
- Agriculture, Soil, Plant Science
- Allelopathy and phytotoxic interactions
- Natural product bioactivities and synthesis
- Plant Disease Management Techniques
- Pharmacological Effects of Natural Compounds
- Plant tissue culture and regeneration
- Analytical Chemistry and Chromatography
- Advanced biosensing and bioanalysis techniques
- Plant Molecular Biology Research
- Food Quality and Safety Studies
- Plant Pathogens and Fungal Diseases
- Genomics, phytochemicals, and oxidative stress
- Plant Disease Resistance and Genetics
- Metabolomics and Mass Spectrometry Studies
- Plant responses to water stress
- Phytochemicals and Antioxidant Activities
- Phytochemistry and Biological Activities
- Plant Stress Responses and Tolerance
- Polysaccharides and Plant Cell Walls
- Plant-Microbe Interactions and Immunity
- Medicinal Plants and Bioactive Compounds
- Electrochemical sensors and biosensors
- Plant-derived Lignans Synthesis and Bioactivity
Changchun University of Chinese Medicine
2017-2025
Tianjin Hospital
2025
Tianjin University
2025
Jilin Provincial Academy of Forestry Science
2024
Shandong Agricultural University
2006-2023
Ministry of Agriculture and Rural Affairs
2023
The implementation of targeted therapies for acute myeloid leukemia (AML) has been challenging. Fat mass and obesity associated protein (FTO), an mRNA N
Breast cancer remains the most frequently diagnosed malignancy among women worldwide. Although effective, numerous treatment strategies have been developed, which suffer from severe side effects due to high toxicity and low specificity. Thus, alternative drugs with promising anti-tumor activity, less toxicity, therapeutic index are highly desirable. Saikosaponin D (SsD), a triterpene saponin derived Bupleurum, exhibit potential properties for therapy. However, systemic toxicities poor...
Continuous cropping obstacles seriously constrained the sustainable development of ginseng industry. The allelopathic autotoxicity ginsenosides is key “trigger” continuous in ginseng. During harvest, plants could be broken and remain soil. decomposition residue soil one important release ways ginsenosides. Therefore, mechanism through decomposed pathway needs an in-depth study. To investigate this regulation mechanism, integrated analysis transcriptomics metabolomics was applied. prototype...
Two polysaccharides were obtained from steamed ginseng via ultrafiltration, and their physical–chemical properties, solution properties antifatigue activities studied. WSGP-S3 WSGP-G3 acid heteropolysaccharides with the molecular weights of 2.03 × 10 4 4.86 , respectively. They composed different molar ratios monosaccharides Rha, GlcA, GalA, Glc, Gal, Ara. The results size-exclusion chromatography–multiangle laser light scattering analysis, Conge red staining Circular dichroism spectroscopy...
Ginseng (Panax ginseng C.A.Meyer) cultivation is hindered by the continuous cropping obstacle, whereby without appropriate rotations yield decline and fields must be abandoned. Organism interactions in rhizosphere alleviate improve obstacles to of ginseng. In this study, high-throughput sequencing gas chromatography coupled with time-of-flight mass spectrometry (GC–TOF-MS) combination analysis soil chemical properties were used investigate microecological changes after 5 years celandine...
Reductive soil disinfestation (RSD) is an effective method to inhibit soilborne pathogens. However, it remains unclear how RSD combined with different types of organic materials affects the ecosystems perennial plants. Pot experiments were conducted investigate effects incorporated perilla (PF), alfalfa (MS), ethanol, and acetic acid on properties, enzyme activities, microbial communities functions, seedling growth. Results showed that RSD-related treatments improved properties changed...
Background Ginseng ( Panax ginseng C. A. Meyer) is a type of plant that cannot be continuously cultivated. Continuous cultivation can lead to the deterioration soil properties, affecting normal growth and development ginseng. Objectives Improving quality breaking down obstacles continuous help sustainable industry. We hope improve cropping through reductive disinfection (RSD), we cultivated in under RSD improvement conditions improved. Materials Methods A 3-year-old field was used as...
Non-small cell lung cancer (NSCLC) is a malignant tumor with high morbidity and mortality. Ginsenosides have been shown to strong antitumor activity, inhibiting growth promoting apoptosis. In this paper, the effects of ginsenoside CK on proliferation apoptosis NSCLC 95D NCI-H460 cells were investigated by CCK8, colony formation assay, flow cytometry, fluorescence staining Western Blot, it was found that could significantly inhibit non-small cancer, also clarified mechanism its action...
Abstract Osteosarcoma (OS), the most prevalent primary malignant bone tumor, is characterized by a poor prognosis and high metastatic potential. Mitochondrial autophagy has been implicated in cancer suppression. This study aimed to identify prognostic genes associated with mitochondrial OS. Public datasets, including TARGET-OS, GSE99671, GSE21257, were retrieved for analysis. Differentially expressed (DEGs1) between OS normal samples identified from GSE99671. Single-sample Gene Set...
The structural conversions in ginsenosides induced by steaming or heating acidic condition could improve red ginseng bioactivities significantly. In this paper, the chemical transformations of American from fresh Panax quinquefolium L. under were investigated, and possible mechanisms discussed. A method with reversed-phase high-performance liquid chromatography coupled linear ion trap mass spectrometry (HPLC-MSn)-equipped electrospray ionization source was developed for analysis quantitation...
Black chokeberry is a deciduous perennial shrub. As kind of berried fruit plants, its sweet and sour with slightly astringent. It not only rich in nutrients but also has high health functions. The fruits black are proanthocyanidins, anthocyanins other polyphenolic bioactive components. Considering the instability components, extraction, purification, determination could influence recovery content evaluation significantly. This paper reviewed compared research on main chemical components...
The allelopathic autotoxicity of ginsenosides is an important cause continuous cropping obstacles in ginseng planting. There no report on the potential molecular mechanism correlation between polarity ginsenoside components and their autotoxicity. This study applied a combination metabolomics transcriptomics analysis techniques, combined with apparent morphology, physiological indexes, cell vitality detection hairy roots, through which were comprehensively studied. roots presented more...
This work aimed at improving the water solubility of Ginsenoside (G)-Re by forming an inclusion complex. The parameters G-Re in alpha (α), beta (β), and gamma (γ) cyclodextrin (CD) were investigated. phase profiles all classified as AL-type that indicated 1:1 stoichiometric relationship with stability constants Ks which 22 M-1 (α-CD), 612 (β-CD), 14,410 (γ-CD), respectively. Molecular docking studies confirmed results binding energy -4.7 -5.10 -6.70 (γ-CD) kcal/mol, complex (IC) was prepared...
Panax ginseng is a valuable traditional herbal medicine material with numerous applications. Ginsenosides are the key bioactive compounds in ginseng. Cold stress can activate tolerance mechanisms that regulate biomass and biosynthesis tissue. In this study, effects of short- long-term cold (5°C) on physiological characteristics, tissue-specific ginsenoside distributions, synthesis gene expressions 3-year-old P. during flowering period were investigated. Short-term significantly reduced (root...
Steamed ginseng water (SGW) is a by-product of the repeated thermal processing red ginseng, which characterized by high bioactive content, better skin care activity, and large output. However, its value has been ignored, resulting in environmental pollution resource waste. In this study, UHPLC-Q-Exactive-MS/MS liquid chromatography–mass spectrometry multivariate statistical analysis were conducted to characterize compositional features thermal-treated SGW. The antioxidant activity (DPPH,...