- Bariatric Surgery and Outcomes
- Esophageal and GI Pathology
- Body Contouring and Surgery
- Esophageal Cancer Research and Treatment
- Obesity and Health Practices
- Gastroesophageal reflux and treatments
- Cardiac, Anesthesia and Surgical Outcomes
- Gastrointestinal disorders and treatments
- Mobile Health and mHealth Applications
- Gastric Cancer Management and Outcomes
- Diet and metabolism studies
- Eating Disorders and Behaviors
- Adipose Tissue and Metabolism
- COVID-19 and healthcare impacts
- Gastrointestinal Tumor Research and Treatment
- Renal and Vascular Pathologies
- Adipokines, Inflammation, and Metabolic Diseases
- Congenital Diaphragmatic Hernia Studies
- Pneumothorax, Barotrauma, Emphysema
- Vascular Tumors and Angiosarcomas
- Climate Change and Health Impacts
- Surgical Simulation and Training
- Mindfulness and Compassion Interventions
- Renal Transplantation Outcomes and Treatments
- Dysphagia Assessment and Management
University Hospitals Coventry and Warwickshire NHS Trust
2013-2024
University of Warwick
2020-2024
National Health Service
2022
University Hospital Coventry
2009-2021
Royal College of Surgeons of England
2020
Coventry (United Kingdom)
2018
L V Prasad Eye Institute
2008-2009
Tata Memorial Hospital
2003
Centre for Sight
1983
Abstract Purpose This IFSO survey aims to describe the current trends of metabolic and bariatric surgery (MBS) reporting on number types surgical endoluminal procedures performed in 2020 2021, world within each chapter. Methods All national societies belonging were asked complete form. The (surgical interventions) from 2021 documented. A special section focused impact COVID-19, existence protocols for MBS, use telemedicine, any mortality related MBS. trend analysis data, both worldwide...
Abstract We analyzed nitric oxide metabolites (nitrate and nitrite, NOx ) other biomarkers in human wound fluids correlated these markers with healing status (progressing or worsening) based on patient's history. Samples were collected pre‐ postcleansing from patients wounds of various etiologies for , matrix metalloproteinase activity, elastase activity. A laboratory method was developed to analyze which can detect at least 5 μM samples as small 10 μL. nitrate‐free sample collection device...
Background Although bariatric surgery is well established as an effective treatment for patients with obesity and type 2 diabetes mellitus (T2DM), there exists reluctance to increase its availability severe T2DM. The aims of this study were examine the impact on T2DM resolution in requiring insulin (T2DM-Ins) using data from a national database develop health economic model evaluate cost-effectiveness cohort when compared best medical (BMT). Methods findings Clinical National Bariatric...
Abstract Background Over 2 million people in England were estimated to be eligible for bariatric surgery 2006. In 2014, clinical guidelines updated, widening potential eligibility, meanwhile, obesity prevalence rose. However, numbers receiving decreased, and concerns exist of inequalities access between population groups. This study is aimed at estimating the number adults compare demographics with those that receive surgery. Methods BMI comorbidity status used determine eligibility within...
Endoscopic sleeve gastroplasty (ESG) is a minimally invasive procedure that has been demonstrated in the MERIT randomised, controlled trial to result substantial and durable additional weight loss adults with obesity compared lifestyle modification (LM) alone. We sought conduct first cost-effectiveness analysis of ESG versus LM alone class II (BMI 35.0-39.9 kg/m2) from national healthcare system perspective England based on results this study.A 6-state Markov model was developed comprising 5...
Mindfulness strategies may facilitate healthier eating behavior but have not previously been studied in a United Kingdom-based tier 3 obesity service. To demonstrate the clinical effectiveness of mindfulness as part newly created group sessions within Recruitment participants (n = 53, including n 33 completers) from patients attending 3–based service at University Hospitals Coventry and Warwickshire. Each participant attended four sessions, which mindfulness-based were taught. Self-reported...
Boerhaave syndrome is a spontaneous perforation of the oesophagus secondary to forceful emesis. Surgery has been advocated in delayed presentations Boerhaave's with mediastinitis. The over-the-scope clip (OTSC) by OVESCO® (Tubingen, Germany) used endoscopic management gastrointestinal bleeds, fistulae and anastamotic leaks. We describe successful use OTSC presentation A 69-year-old gentleman underwent computerised tomography scan, which demonstrated lower oesophageal mediastinitis 7 days...
Visfatin is an adipogenic adipokine with increased levels in obesity, properties common to leptin. Thus, leptin may modulate visfatin production adipose tissue (AT). Therefore, we investigated the effects of on 3T3-L1 adipocytes and human/murine AT, or without a antagonist. The potential signaling pathways mechanisms regulating AT was also studied. Real-time RT-PCR Western blotting were used assess relative mRNA protein expression visfatin. ELISA performed measure conditioned media explants,...
Abstract Coronavirus Disease-2019 (COVID-19) has had a severe impact on all aspects of global healthcare delivery. This study aimed to investigate the nationwide pandemic obesity management services in UK questionnaire-based survey conducted professionals involved A total 168 clinicians took survey; majority which maintained their usual clinical roles and were not redeployed except physicians nurse specialists. Nearly (97.8%) elective bariatric surgery was cancelled, 67.3% units cancelled...
Abstract Background Obesity is a chronic relapsing-remitting disease and global pandemic, being associated with multiple comorbidities. Laparoscopic adjustable gastric banding (LAGB) one of the safest surgical procedures used for treatment obesity, even though its popularity has been decreasing over time, it still remains an option certain group patients, producing considerable weight loss improvement in obesity-associated Methods The aim this study was to evaluate impact following LAGB on...
Background: Obesity may affect both biochemical thyroid function tests; and morphology, as assessed using ultrasound scans (US). The aim of the present pilot study was to explore whether weight loss achieved by bariatric surgery alters US morphology including grey-scale measurements; and/or in euthyroid adults with severe obesity. Methods: Euthyroid (>18 years) body mass index (BMI) ≥40 kg/m2 negative peroxidase antibodies were at baseline (pre-surgery) after achieving least 5% their...
The case is a 34-year-old woman with long-standing type 1 diabetes mellitus existing follow-up in the outpatient clinic at Warwickshire Institute for Study of Diabetes, Endocrinology and Metabolism, UHCW. She had maintained good glycaemic control stability basal bolus regimen many years. not developed any diabetes-related complications no other co-morbidities. Six months ago, she presented to A&E sudden-onset, well-localised severe pain right iliac fossa, just lateral para-umbilical area....
Abstract Objective Age is sometimes a barrier for acceptance of patients into hospital‐based obesity service. Our aim was to explore the effect age on ability lose weight through lifestyle interventions, implemented within Design Retrospective study. Patients We included cohort randomly selected with morbid ( n = 242), who attended our service during 2005‐2016 and received only loss interventions. Measurements Primary outcome measures were percentage (%WL) reduction in body mass index...
Bouveret's syndrome is an uncommon condition characterized by the impaction of a gallstone in pylorus or duodenum via cholecysto-enteric fistula causing gastric outlet obstruction. We report two unusual cases obstruction elderly patients.
A 63-year-old man attended the accident and emergency department with chest pain breathlessness following an episode of severe vomiting after excess alcohol intake. Clinical examination radiography confirmed a left-sided tension pneumothorax requiring thoracocentesis drain placement. Computed tomography (CT) scan intravenous contrast showed pneumomediastinum, which suggested possibility esophageal rupture in absence external trauma. CT oral performed subsequently, leakage from lower...