A5012613845- Heavy metals in environment
- Lipid metabolism and biosynthesis
- Plant Stress Responses and Tolerance
- Arsenic contamination and mitigation
- Agriculture and Rural Development Research
- Invertebrate Taxonomy and Ecology
- Nitrogen and Sulfur Effects on Brassica
- Heavy Metals in Plants
- Cellular transport and secretion
- African Botany and Ecology Studies
- Soil Carbon and Nitrogen Dynamics
- Heavy Metal Exposure and Toxicity
- Endoplasmic Reticulum Stress and Disease
- Mine drainage and remediation techniques
- French Urban and Social Studies
- Mitochondrial Function and Pathology
- Plant Molecular Biology Research
- Photosynthetic Processes and Mechanisms
- Plant nutrient uptake and metabolism
- ATP Synthase and ATPases Research
- Metabolomics and Mass Spectrometry Studies
- Diatoms and Algae Research
- Plant responses to elevated CO2
- Seed Germination and Physiology
- Plant Ecology and Soil Science
Université de Bordeaux
2010-2025
Centre National de la Recherche Scientifique
2008-2025
Laboratoire de Biogenèse Membranaire
2012-2025
ADERA
2013-2025
Agence pour le développement de l'emploi
2016-2018
Institut National de la Recherche Agronomique du Niger
2017
Abstract Contrasting with the wealth of information available on multiple roles jasmonates in plant development and defense, knowledge about functions biosynthesis hydroxylated oxylipins remains scarce. By expressing caleosin RESPONSIVE TO DESSICATION20 (RD20) Saccharomyces cerevisiae, we show that recombinant protein possesses an unusual peroxygenase activity restricted specificity toward hydroperoxides unsaturated fatty acid. Accordingly, Arabidopsis (Arabidopsis thaliana) plants...
Chronic exposure to arsenic may be detrimental health. We investigated the behaviour, remediation and risk management of in Freiberg, Germany, characterized by past mining activities, near Verdun France, where World War I ammunition was destroyed. The main results included: (1) pot experiments using a biologically synthesized adsorbent (sorpP) with spring barley reduced mobility arsenic, (2) Omega-3 Index ecotoxicological tests verified that sorpP uptake toxicity plants, (3) reverse osmosis...
Securing mine tailings represents a major environmental challenge. Metal mines frequently produce solid wastes containing iron (Fe) and sulfur (S), often associated with the toxic metalloid arsenic (As). Phytostabilisation appears as suitable option to decrease dispersion of particles by erosion, at moderate cost. However, site managers need more comprehensive view all consequences linked this remediation technique, notably side effects on other pathways controlling As metals mobility out...
In yeast, both phosphatidylinositol and phosphatidylserine are synthesized from cytidine diphosphate-diacylglycerol. Because, as in other eukaryotes, contains more saturated fatty acids than (and phospholipids), it has been hypothesized that either is distinct diphosphate-diacylglycerol molecules, or that, after its synthesis, modified by a hypothetical acyltransferase incorporates acid into neo-synthesized molecules of phosphatidylinositol. We used database search methods to identify an...
For many years, lipid droplets (LDs) were considered to be an inert store of lipids. However, recent data showed that LDs are dynamic organelles playing important role in storage and mobilization neutral In this paper, we report the characterization LOA1 (alias VPS66, alias YPR139c), a yeast member glycerolipid acyltransferase family. mutants show abnormalities LD morphology. As previously reported, cells lacking contain more LDs. Conversely, overexpression results fewer We then compared...
Because Lactuca sativa L. is a plant widely used in ecotoxicological analyses, study was developed to determine whether the fatty acid composition of lettuce leaves could be as an additional biomarker soil contamination by metals such Pb, Cu, Zn, and Cd. Unlike seed germination or seedling growth, differed significantly between uncontaminated field metal-contaminated soils. Hence, this lipid might provide early indication plant's exposure potential bioavailability metals, facilitate...
<i>N</i>-Acylethanolamines (NAEs) are lipids involved in several physiological processes animal and plant cells. In brain, NAEs ligands of endocannabinoid receptors, which modulate various signaling pathways. plant, regulate seed germination root development, they defense against pathogen attack. This activity is started by an enzyme called <i>N</i>-acylphosphatidylethanolamine (NAPE) synthase. catalyzes the <i>N</i>-acylation phosphatidylethanolamine to form NAPE, most likely hydrolyzed...
Decreasing cytosolic translation is beneficial to yeast and human Tafazzin-deficient cells – INTRODUCTION The Barth Syndrome (BTHS) a rare X-linked recessive mitochondrial disorder that characterized by cardiac skeletal myopathies, growth retardation, hypocholesterolemia, increased urine levels of 3-methylglutaconic acid high susceptibility bacterial infections, due cyclic neutropenia . This disease caused mutations in Tafazzin, protein involved the remodeling (...)
A non-synonymous mtDNA mutation, m.3395A > G, which changes tyrosine in position 30 to cysteine p.MT-ND1, was found several patients with a wide range of clinical phenotypes such as deafness, diabetes and cerebellar syndrome but no Leber's hereditary optic neuropathy. Although this mutation has already been described, its pathogenicity not demonstrated. Here, it isolated for the first time, allowing study investigate pathogenicity. To do so, we constructed cybrid cell lines carried out...
Abstract Phosphatidic acid (PA) and lysophosphatidic acyltransferases (LPAATs) might be critical for the secretory pathway. Four extra-plastidial LPAATs (LPAAT2, 3, 4, 5) were identified in Arabidopsis thaliana. These AtLPAATs display a specific enzymatic activity converting to PA are located endomembrane system. We investigate putative role 5 pathway of root cells through genetical (knockout mutants), biochemical (activity inhibitor, lipid analyses), imaging (live immuno-confocal...
Lyso-lipid acyltransferases are enzymes involved in various processes such as lipid synthesis and remodelling. Here, we characterized the activity of an acyltransferase from Arabidopsis thaliana (LPIAT). In vitro, this protein, expressed Escherichia coli membrane, displayed a 2-lyso-phosphatidylinositol with specificity towards saturated long chain acyl CoAs (C16:0- C18:0-CoAs), allowing remodelling phosphatidylinositol. planta, LPIAT gene was mature seeds very transiently during seed...