A5002487268- Rock Mechanics and Modeling
- Geomechanics and Mining Engineering
- Genetic Mapping and Diversity in Plants and Animals
- Geoscience and Mining Technology
- Genetics and Neurodevelopmental Disorders
- Cervical Cancer and HPV Research
- Autism Spectrum Disorder Research
- Rice Cultivation and Yield Improvement
- GABA and Rice Research
- Plant Disease Resistance and Genetics
- Mineral Processing and Grinding
- Genomic variations and chromosomal abnormalities
- Geotechnical Engineering and Analysis
- Coal Properties and Utilization
- Landslides and related hazards
- Tunneling and Rock Mechanics
- Viral Infections and Vectors
- Tailings Management and Properties
- Civil and Geotechnical Engineering Research
- Structural Response to Dynamic Loads
- Grouting, Rheology, and Soil Mechanics
- Atmospheric chemistry and aerosols
- Nuclear Structure and Function
- Blasting Impact and Analysis
- Vector-Borne Animal Diseases
China University of Mining and Technology
2016-2025
Chinese University of Hong Kong
2022
Shantou University
2022
New York State Office for People With Developmental Disabilities
1991-2019
Shanghai Electric (China)
2019
Fujian Provincial People's Hospital
2019
Xinxiang Medical University
2018
Wuhan University
2009-2013
Wuhan Institute of Virology
2009-2013
State Key Laboratory of Virology
2013
Naturally occurring allelic variations underlying complex traits are useful resources for the functional analysis of plant genes. To facilitate genetic and use marker-assisted breeding in rice, we developed a wide population consisting 217 chromosome single-segment substitution lines (SSSLs) using Oryza sativa L. 'Hua-Jing-Xian74' (HJX74), an elite Indica cultivar, as recipient, 6 other accessions, including 2 4 Japonica, donors. Each SSSL contains single substituted segment derived from 1...
Objective To determine risks of expansion for normal, intermediate, and premutation FMR1 CGG repeats. Methods PCR was used to compare the alleles in prenatal (chorionic villi amniocytes) parental samples collected from 1991 2010. Prenatal diagnoses were confirmed by Southern analysis. Results Fragile X analysis 1112 pregnancies identified 558 106 216 premutation, 232 full mutation fetuses. Of 509 maternal, alleles, 350 (68.7%) unstable on transmission with expansions ranging one repeat...
Though machine learning (ML) approaches have proliferated in the mechanical properties prediction of cemented paste backfill (CPB), their applications not reached peak potential due to lack more robust techniques. In present contribution, state-of-the-art ensemble method was employed for improved estimation unconfined compressive strength (UCS) CPB. 126 UCS tests were conducted on two new tailings provide an enlarged dataset. Tree-based ML approaches, namely, regression tree (RT), random...
Shear strength (SS) parameters are essential for understanding the mechanical behavior of materials, particularly in geotechnical engineering and rock mechanics. This study proposes a novel hierarchical ensemble model (HEM) to predict SS parameters: cohesion ( $$C$$ ) angle internal friction $$\varphi$$ ). The HEM addresses limitations traditional machine learning models. Its performance was validated using leave-one-out cross-validation (LOOCV) out-of-bag (OOB) evaluation methods. model's...
The instability of geological slopes in mining environments poses a significant challenge to the safety and efficiency operations. Waste Dump#2 at Ziluoyi Iron Mine China is notable case study that highlights challenges associated with sizable base large step heights. To address hidden hazards mine above issues, an inclusive investigation carried out examine physical mechanical properties soil–rock slope through indoor testing analyze deformation mechanisms using numerical simulations,...
The ore mining sites commonly experience slope instability, which is causing concern for the workers' safety and operation's stability. Considering Ziluoyi iron site as a case study, uniaxial compression strength shear tests are performed on lower disk peripheral rock, body, upper leading to extraction of compressive elastic modulus (lower disk: 77.7 MPa–9.093 GPa; body: 19.6 MPa–4.619 55.47 MPa–5.573 GPa). Further, using Hoek–Brown criterion in conjunction with Moher–Columb criterion,...
Studies have identified mutations in >50 genes that can lead to monogenic steroid-resistant nephrotic syndrome (SRNS). The NUP160 gene, which encodes one of the protein components nuclear pore complex nucleoporin 160 kD (Nup160), is expressed both human and mouse kidney cells. Knockdown impairs podocytes cell culture. Recently, siblings with SRNS proteinuria a nonconsanguineous family were found carry compound-heterozygous NUP160.We by whole-exome Sanger sequencing genomic DNA from young...
Car-sharing is becoming an increasingly popular travel mode in China and many companies invest plenty of money on that including vehicle enterprises Internet companies. But most them build car-sharing stations by their experience or randomly as long there parking space the early development business. This results with low operational efficiency causes capital loss. study aims to use different data source statistical models machine learning algorithm help operator choose optimal location new...
This research proposes a new dust reduction method based on water infusion blasting in order to effectively minimize the production during open-pit mines. The proposed was applied at Haerwusu coal mine, China. A high-speed camera used record dynamic process of generation blasting. images acquired from main locations were analyzed using gray level recognition MATLAB. then numerically simulated ANSYS/Fluent software. Finally, field experiment conducted verify by analyzing its efficiency....
During the past three years, we have conducted fragile X DNA studies for carrier screening and prenatal diagnosis using a previously described PCR protocol that accurately resolves normal FMR1 alleles premutations detects most full mutations [Brown et al., JAMA 270:1569–1575, 1996]. A total of 344 pregnant women with family history mental retardation unknown cause were screened 6 carriers identified: two had mutations, four premutations. The mentally retarded relatives other found to be...
Fragile X syndrome is one of the most common forms inherited mental retardation, and first a new class genetic disorders associated with expanded trinucleotide repeats. Previously, we found that about 41% affected males are mosaic for this mutation in some their blood cells have an active fragile gene others do not. It has been hypothesized these cases should show higher levels functioning than those who only inactive full gene, but previous studies provided negative or equivocal results. In...
Folium isatidis is a native Chinese herbaceous plant widely used for medicinal purposes thousands of years. However, few studies have focused on the leaves Isatis indigotica. In this report, we isolated series four fractions (I–IV) from and explored antiviral activity each tested extract. The extracts were active against panel RNA DNA viruses in vitro, namely influenza A virus (IAV), coxsackie B3 (CVB3), respiratory syncytial (RSV), adenovirus type 7 (Ad-7). Oral administration 200 mg/kg/d...