A5101716771- MicroRNA in disease regulation
- Cancer-related molecular mechanisms research
- Soil Carbon and Nitrogen Dynamics
- RNA Research and Splicing
- Covalent Organic Framework Applications
- Advanced Photocatalysis Techniques
- Oral microbiology and periodontitis research
- Immune Response and Inflammation
- RNA modifications and cancer
- Metal-Organic Frameworks: Synthesis and Applications
- Soil and Water Nutrient Dynamics
- Marine Sponges and Natural Products
- Fungal and yeast genetics research
- Natural product bioactivities and synthesis
- Plant biochemistry and biosynthesis
- Ecology and Vegetation Dynamics Studies
- Coastal wetland ecosystem dynamics
- Traditional and Medicinal Uses of Annonaceae
- Inflammatory mediators and NSAID effects
- Surface Modification and Superhydrophobicity
- Enzyme-mediated dye degradation
- Biotin and Related Studies
- Microbial Natural Products and Biosynthesis
- Synthetic Organic Chemistry Methods
- Clay minerals and soil interactions
Northwest Normal University
2022-2024
Southern University of Science and Technology
2024
Nanjing University
2023-2024
Guilin University of Technology
2023
Wuyi University
2022
Tiangong University
2022
Hebei North University
2013-2019
China Pharmaceutical University
2016-2018
Tohoku University
2012
The fusicoccane diterpenoids have triggered particular interest from the organic synthesis community in recent years, owing to their promising biological profiles and complex chemical structures. Here, we report collective, asymmetric total syntheses of five diterpenoids, namely fusicoauritone, fusicogigantones A B, fusicogigantepoxide, anadensin. This work features a Yu [5+2+1] cycloaddition that is shown be swift approach access [5,8]-bicyclic ring system an oxidative Nazarov cyclization...
Abstract Periodontitis is a chronic inflammatory and immune reactive disease induced by the subgingival biofilm. The therapeutic effect for susceptible patients often unsatisfactory due to excessive response oxidative stress. Sinensetin (Sin) nature polymethoxylated flavonoid with anti-inflammatory antioxidant activities. Our study aimed explore beneficial of Sin on periodontitis specific molecular mechanisms. We found that attenuated stress levels periodontal ligament cells (PDLCs) under...
Biochar amendment has been proposed as a strategy to improve acidic soils after overuse of nitrogen fertilizers. However, little is known the role biochar in soil microbial biomass carbon (MBC) and bacterial community structure diversity acidification induced by (N) deposition. Using high-throughput sequencing 16S rRNA gene, we determined effects (BC0, 0 t bamboo ha−1; BC20, 20 BC40, 40 ha−1) on Moso plantations that had received simulated N deposition (N30, 30 kg ha−1 yr−1; N60, 60 N90, 90...
Comprehensive Summary As one of the most common structural motifs in natural products, cyclopentenones usually can be fabricated by Nazarov cyclization using divinyl ketones or functionalized tertiary carbinols (TDCs) as substrates. However, straightforward method for transforming unfunctionalized TDCs to their corresponding is currently lacking. Herein, we wish report total syntheses four structurally distinct terpenoids, namely laurane‐type marine sesquiterpenoids isolaurene,...
RNA binding proteins (RBPs) are pivotal post-transcriptional regulators. RNPC1, an RBP, acts as a tumor suppressor through and regulating the expression of target genes in cancer cells. This study disclosed that RNPC1 was positively correlated with breast patients' relapse-free overall survival suppressed cell metastasis. Mechanistically, promotes competing endogenous (ceRNA) network crosstalk among STARD13, CDH5, HOXD10, HOXD1 (STARD13-correlated ceRNA network), which we previously...
Diverse RNA transcripts acting as competing endogenous RNAs (ceRNAs) can co-regulate each other's expression by for shared microRNAs. CCR2 protein, the receptor CCL2, is implicated in cancer progression. However, we found that a higher mRNA level remarkably associated with prolonged survival of breast patients. These conflicting results prompted us to study non-coding function mRNA. We 3' untranslated region (UTR) inhibited MDA-MB-231 and MCF-7 cell metastasis repressing...
The balance of pro- and antiapoptotic gene expression programs dominates the apoptotic progress cancer cells. We previously demonstrated that STARD13 3'UTR suppressed breast metastasis via inhibiting epithelial-mesenchymal transition (EMT). However, roles in apoptosis remain elusive. Here, we identified promoted cell vitro vivo. Mechanistically, acted as a ceRNA for BMF (Bcl-2 modifying factor), thus increasing an miRNA-dependent manner. Meanwhile, enhanced interaction BMF/Bcl-2 to release...
Dissolved organic matter (DOM) is one of the most reactive and mobile components in terrestrial ecosystems. Frequent loss DOM has a negative effect on surrounding environment. Current abundant deposition atmospheric nitrogen (N) could significantly influence leaching, biochar been suggested to be applied for improving acidic soils However, it remains unclear whether affects dissolved carbon (DOC) or (DON) induced by N soils. In this study, we observed effects amendment (BC0: 0 t ha−1, BC20:...
The recyclable metallic imidazolium-based ionic liquid-catalyzed mono-hydroboration of imines, double-hydroboration imine with aldehyde, and aniline glutaric dialdehyde in the presence HBpin water is described for first time. liquid [BMIm][FeCl4] showed excellent activity, high selectivity, good recyclability catalytic hydroborations. This system widely tolerated various functional rings unsaturated groups without additional reduction. Furthermore, could be reused more than 15 runs decay activity.
Soil enzymes are the metabolic motors for soil organisms. However, how respond to biochar amendment in plantations under increasing chronic atmospheric nitrogen (N) deposition is poorly understood. In this study, we analyzed effects of N (30, 60, and 90 kg ha−1 yr−1 treatments N30, N60 N90, respectively) (20 40 t BC20 BC40, on six enzyme activities (β-fructofuranosidase, cellulase, nitrate reductase, nitrite urease, acid phosphatase) a Moso bamboo (Phyllostachys edulis (Carrière) J. Houz)...
Herein, covalent triazine frameworks in eclipsed AA and staggered AB stacking modes are respectively used for the in-situ growth of TiO
The myeloblastosis ( MYB ) transcription factors (TFs) participate in a variety of physiological and biochemical processes, especially the anthocyanin biosynthesis plants. However, comprehensive functional study TFs, regulating accumulation passion fruit Passiflora edulis remains limited. To gain better understanding evolutionary history this family, we conducted genome-wide analysis TFs fruit, including phylogenetic analysis, gene structure, conserved motifs, chromosomal locations,...
<title>Abstract</title> Periodontitis is a chronic inflammatory and immune reactive disease induced by the subgingival biofilm. The therapeutic effect for susceptible patients often unsatisfactory due to excessive response oxidative stress. Sinensetin (Sin) nature polymethoxylated flavonoid with anti-inflammatory antioxidant activities. Our study aimed explore beneficial of Sin on periodontitis specific molecular mechanisms. We found that attenuated stress levels periodontal ligament cells...