A5100349122- Congenital Heart Disease Studies
- Cardiac Valve Diseases and Treatments
- Coronary Artery Anomalies
- Cardiovascular Issues in Pregnancy
- Cardiac Structural Anomalies and Repair
- Cardiovascular and Diving-Related Complications
- Immune Response and Inflammation
- Cardiac Arrhythmias and Treatments
- Spine and Intervertebral Disc Pathology
- Hepatocellular Carcinoma Treatment and Prognosis
- Cardiovascular Conditions and Treatments
- Oral microbiology and periodontitis research
- Congenital heart defects research
- Pulmonary Hypertension Research and Treatments
- Cardiac Imaging and Diagnostics
- Extracellular vesicles in disease
- Organ Transplantation Techniques and Outcomes
- Vascular Malformations and Hemangiomas
- Oropharyngeal Anatomy and Pathologies
- Cancer survivorship and care
- Tracheal and airway disorders
- Inflammatory mediators and NSAID effects
- Cancer Mechanisms and Therapy
- Spinal Hematomas and Complications
- Cervical and Thoracic Myelopathy
Nanjing University
2023-2024
Institute of Hematology & Blood Diseases Hospital
2023
Army Medical University
2022
Guangdong Academy of Medical Sciences
2012-2021
Guangdong Provincial People's Hospital
2006-2021
Committee on Publication Ethics
2021
Integrated Chinese Medicine (China)
2021
Tianjin First Center Hospital
2020
Tianjin Medical University
2020
Pulmonary Hypertension Association
2019
Chemoresistance to temozolomide (TMZ) is a major challenge in the treatment of glioblastoma (GBM). We previously found that miR-519a functions as tumor suppressor glioma by targeting signal transducer and activator transcription 3 (STAT3)-mediated autophagy oncogenic pathway. Here, we investigated effects on TMZ chemosensitivity GBM cells. Furthermore, underlying molecular mechanisms signaling pathways were explored.In present study, two stable TMZ-resistant cell lines successfully generated...
Abstract Periodontitis is a chronic inflammatory and immune reactive disease induced by the subgingival biofilm. The therapeutic effect for susceptible patients often unsatisfactory due to excessive response oxidative stress. Sinensetin (Sin) nature polymethoxylated flavonoid with anti-inflammatory antioxidant activities. Our study aimed explore beneficial of Sin on periodontitis specific molecular mechanisms. We found that attenuated stress levels periodontal ligament cells (PDLCs) under...
Coronavirus disease 2019 (COVID-19) was declared a serious global public health emergency. Hospitalization and mortality rates of lung cancer patients diagnosed with COVID-19 are higher than those presenting other cancers. However, the reasons for outcomes being disproportionately severe in adenocarcinoma (LUAD) remain elusive. The present study aimed to identify possible causes LUAD determine therapeutic target LUAD. We used publicly available data from Cancer Genome Atlas (TCGA) Gene...
Pulmonary artery hypertension associated with congenital heart disease (PAH-CHD) occurs predominantly among patients uncorrected CHD. Treatment of severe pediatric PAH-CHD remains a major intractability. This study evaluated the predictors and prognoses children who underwent surgical correction.The data for 59 correction, or without postoperative medication, between May 2011 June 2015 at Guangdong Provincial People's Hospital were analyzed retrospectively. A regression analysis,...
Background. With the rapid development of transcatheter techniques and instruments, occlusion for patients with perimembranous ventricular septal defect (pVSD) aortic valve prolapse (AVP) was constantly being tried, while efficacy safety pVSD AVP remain controversial. Objective. The aim this study to evaluate long-term AVP. Methods. We retrospectively analyzed 164 children who underwent between January 2013 November 2014. divided into 3 degrees according right coronary leaflet morphology at...
Background: Percutaneous balloon pulmonary valvuloplasty (PBPV) is the preferred therapy for valve stenosis (PVS). This study retrospectively reviewed recent PBPV outcomes in infants with PVS. The aim of this was to evaluate factors associated immediate therapeutic and restenosis during medium-term follow-up. Methods: included 158 PVS who underwent from January 2009 July 2015. Demographic characteristics patient records were reviewed, including detailed hospitalization parameters,...
Transcatheter closure of aneurysmal perimembranous ventricular septal defect (pmVSD), pmVSD near the aortic valve, and intracristal VSD (icVSD) with symmetrical or asymmetrical occluders still presents significant challenges. We report our experience transcatheter icVSD using Amplatzer duct occluder II (ADO II) in children.We retrospectively analyzed all children, who presented to hospital consecutively between March 2014 June 2020 for attempted ADO device. Standard safety last-follow-up...
We aimed to explore the radiologic characteristics and interventional strategies for perimembranous ventricular septal defect (pmVSD) with aneurysm.257 patients who underwent transcatheter closure of pmVSD aneurysm were included in our study. retrospectively reviewed left opening (a), diameter midsegment (b), right (c). If there multiple defects within aneurysm, largest was denoted as c1 so forth. developed a novel VSD classification method which classified into three types (A, B, C). When...
Objective To evaluate the efficacy and experience in right ventricular pacing-percutaneous balloon aortic valvuloplasty (RVP-PBAV) for congenital stenosis (AS). Method A total of sixteen children with AS accepted treatment RRVP-PBAV. The patients were at ages 6 months to 15 years, their median age was 5.4 years. Their body weight between 8.5 59.0 kg, average (22.3±16.5) kg. gradient pressure across valve measured all regurgitation observed. follow-up time ranged from 1 month 5.5...
Abstract Background The patient-reported outcomes measurement information system 29-item profile (PROMIS-29) is a widely utilized self-reported instrument for assessing health from the patients’ perspectives. This study aimed to evaluate psychometric properties of PROMIS-29 Chinese version among patients with hematological malignancy. Methods Conducted as cross-sectional, this research was approved by Medical Ethical Committee Institute Hematology & Blood Diseases Hospital, Academy...
Objective To observe the curative effect of herbal iontophoresis with rotation manipulation treating lumbar disc herniation.Methods 84 patients from July 2011 to 2012 lumber herniation in Electric Power hospital Capital Medical University were randomly divided into two groups (a testing group n=42,a control n=42).The was treated and manipulation,and only.The Visual Analogue Scale Macnab standard for observed before treatment 3 weeks later after treatment.Results The total effective rate...
<title>Abstract</title> Periodontitis is a chronic inflammatory and immune reactive disease induced by the subgingival biofilm. The therapeutic effect for susceptible patients often unsatisfactory due to excessive response oxidative stress. Sinensetin (Sin) nature polymethoxylated flavonoid with anti-inflammatory antioxidant activities. Our study aimed explore beneficial of Sin on periodontitis specific molecular mechanisms. We found that attenuated stress levels periodontal ligament cells...