A5100427065- Congenital Heart Disease Studies
- Coronary Artery Anomalies
- Gastric Cancer Management and Outcomes
- Cardiovascular and Diving-Related Complications
- Tracheal and airway disorders
- Vascular anomalies and interventions
- Metastasis and carcinoma case studies
- Pulmonary Hypertension Research and Treatments
- Kawasaki Disease and Coronary Complications
- Aortic Disease and Treatment Approaches
- Thermoregulation and physiological responses
- Cancer-related molecular mechanisms research
- Electrospun Nanofibers in Biomedical Applications
- Cardiac electrophysiology and arrhythmias
- Cardiac Structural Anomalies and Repair
- Vascular Anomalies and Treatments
- Infrared Thermography in Medicine
- Bee Products Chemical Analysis
- Antibiotics Pharmacokinetics and Efficacy
- Abdominal Trauma and Injuries
- Pain Mechanisms and Treatments
- Renin-Angiotensin System Studies
- Medicinal Plant Pharmacodynamics Research
- Ureteral procedures and complications
- Thermal Regulation in Medicine
Hangzhou Medical College
2025
Fujian Medical University
2023-2024
Union Hospital
2023-2024
Guangdong Provincial People's Hospital
2019-2024
Nanjing University of Chinese Medicine
2024
Guangdong Academy of Medical Sciences
2017-2024
Southern Medical University
2023-2024
China-Japan Friendship Hospital
2024
Hangzhou Normal University
2024
Texas Tech University
2024
Indocyanine green (ICG) fluorescence imaging-guided lymphadenectomy has been demonstrated to be effective in increasing the number of lymph nodes (LNs) retrieved laparoscopic gastrectomy for gastric cancer (GC). Previously, we reported primary outcomes and short-term secondary a phase 3, open-label, randomized clinical trial (NCT03050879) investigating use ICG image-guided patients with potentially resectable GC. Patients were randomly (1:1 ratio) assigned either or non-ICG group. The...
Importance Recombinant human prourokinase (rhPro-UK) is a thrombolytic agent that has shown promising findings in phase 2 clinical trial patients with acute ischemic stroke (AIS). Objective To evaluate the efficacy and safety of rhPro-UK thrombolysis within 4.5 hours symptom onset AIS. Design, Setting, Participants This randomized, alteplase-controlled, open-label, 3 was conducted from May 2018 to 2020 at 35 medical centers China. A total 684 were screened 674 enrolled. Included aged 18 80...
ZnMn 2 O 4 with Zn vacancies has been constructed via alkaline etching, which shows lower diffusion energy barriers for 2+ than .
Long noncoding RNAs (lncRNAs) have been confirmed to be potential prognostic markers in a variety of cancers and interact with microRNAs (miRNAs) as competing endogenous (ceRNAs) regulate target gene expression. However, the role lncRNA‑mediated ceRNAs breast cancer (BC) remains unclear. In present study, ceRNA network was generated explore their BC. The expression profiles mRNAs, miRNAs lncRNAs 1,109 BC tissues 113 normal were obtained from Cancer Genome Atlas database (TCGA). A total 3,198...
Abstract Background Glioma is one of the leading types brain tumor, but few etiologic factors primary glioma have been identified. Previous observational research has shown an association between viral infection and risk. In this study, we used Mendelian randomization (MR) analysis to explore direction magnitude causal relationship glioma. Methods We conducted a two-sample bidirectional MR using genome-wide study (GWAS) data. Summary statistics data were collected from largest meta-analysis...
Precancerous metaplasia transition to dysplasia poses a risk for subsequent intestinal-type gastric adenocarcinoma. However, the molecular basis underlying transformation from metaplastic cancerous cells remains poorly understood.
This study aimed to investigate the status of carbapenem-resistant strains Klebsiella pneumoniae isolated from Department Microbiology, Zhejiang Tongde Hospital between September 2023 and February 2024, examine in vitro antibacterial effect Reduning combined with polymyxin on (CRKP), which may provide evidence application clinical anti-infective therapy. A total 50 different isolates CRKP were collected, minimum inhibitory concentrations (MIC) polymyxin, plus measured microbroth dilution...
Abstract Gastric cancer stem cells (GCSCs) are self‐renewing tumor that govern chemoresistance in gastric adenocarcinoma (GAC), whereas their regulatory mechanisms remain elusive. Here, the study aims to elucidate role of ATOH1 maintenance GCSCs. The preclinical model and GAC sample analysis indicate deficiency is correlated with poor prognosis chemoresistance. ScRNA‐seq reveals downregulated pit compared those paracarcinoma samples. Lineage tracing Atoh1 deletion strongly confers cell...
Spontaneous renal parenchymal rupture is a rare clinical emergency. The formation of benign and malignant tumors the most common underlying cause spontaneous parenchyma. To best our knowledge, 15 cases have been reported to date. This report describes case parenchyma in lower left kidney caused by calculi. Furthermore, previously published articles were reviewed. patient underwent four extracorporeal shockwave lithotripsy procedures within 2 years. stones was successfully treated removing...
Abstract Objective To evaluate the feasibility, safety, and effectiveness of a novel, absorbable atrial septal defect (ASD) closure device made poly‐ l ‐lactic acid (PLLA) in swine model ASD for first time humans. Methods A preclinical safety study was conducted using ASD. In clinical setting, five pediatric patients underwent with PLLA fluoroscopic transthoracic echocardiography guidance. The procedural results outcomes at 1 day, 30 days, 3 months, 6 months after were analyzed. Results 24‐...
To investigate the circadian changes of autonomic function in patients with zoster-associated pain (ZAP).
Cumulative blood pressure (BP) exposure is a known risk factor for cardiovascular disease. This study sought to investigate the association between cumulative BP from early adulthood middle age and right ventricular (RV) structure function in age.We included 2844 participants CARDIA (Coronary Artery Risk Development Young Adults). over 30-years follow-up was defined as sum of product mean each pair consecutive examinations time interval these two years. RV were assessed by echocardiography....
This study aims to investigate the level of cAMP response element-binding protein 1 (phospho S133) (p-CREB1) in clear cell renal carcinoma (ccRCC) and evaluates its prognosis significance.Immunohistochemistry (IHC) method was performed detect p-CREB1 staining 233 ccRCC patients. Three or more high-power fields per tissue section were equally captured by a Leica DMRXA microphotographic system, average intensity (optical density, OD) analyzed Qwin Standard V2.6 system. Univariate multivariate...
Background: Percutaneous balloon pulmonary valvuloplasty (PBPV) is the preferred therapy for valve stenosis (PVS). This study retrospectively reviewed recent PBPV outcomes in infants with PVS. The aim of this was to evaluate factors associated immediate therapeutic and restenosis during medium-term follow-up. Methods: included 158 PVS who underwent from January 2009 July 2015. Demographic characteristics patient records were reviewed, including detailed hospitalization parameters,...
Transcatheter closure of congenital coronary artery fistulas (CCAFs) is an alternative therapy to surgery; however, data regarding transcatheter for CCAF with a giant aneurysm (CAA) in pediatric patients are still limited due the rarity disease. We aimed evaluate efficacy and safety CAA population at single center.Medical records (<18 years old) who underwent between April 2007 September 2016 Guangdong Cardiovascular Institute (Guangdong, China) were reviewed.Twelve (median age, 6.1 years;...
This study presented a three-dimensional magnetic resonance (MR)-based method to separate breast into four quadrants for quantitative measurements of the quadrant volume (BV) and density.Breast MR images from 58 healthy women were studied. The fibroglandular tissue segmented by using computer-based algorithm. A was divided two perpendicular planes intersecting at nipple or nipple-centroid line. After separation, BV, volume, percent density (PD) calculated. symmetry BV in left right breasts...
We aimed to explore the radiologic characteristics and interventional strategies for perimembranous ventricular septal defect (pmVSD) with aneurysm.257 patients who underwent transcatheter closure of pmVSD aneurysm were included in our study. retrospectively reviewed left opening (a), diameter midsegment (b), right (c). If there multiple defects within aneurysm, largest was denoted as c1 so forth. developed a novel VSD classification method which classified into three types (A, B, C). When...
We reported the 3-year follow-up results of initial clinical experience with AbsnowTM device, a novel biodegradable occluder for percutaneous closure atrial septal defect (ASD).The device is total double-disc poly-L-lactic acid (PLLA) framework and PLLA membranes intergraded into to ensure its biodegradability, safety, efficacy.Five pediatric patients were enrolled from May June 2018 in our institution followed up 3 years. A evaluation transthoracic echocardiography performed at 24 hr, 1...
We compared four repair techniques for impaired ankle ligament deltoideum, namely Wiltberger, Deland, Kitaoka and Hintermann using a 3-dimensional finite element. built an deltoideum model, including six pieces of bone structures, gristles main ligaments around the ankle. After testing we model plus reconstruction models. Subsequently, different levels force on ankles with flexion were imposed biomechanics compared. In course bending, from plantar 20° to back 20°, extortion talus decreased...
Objective: To investigate the effect and mechanism of Danshen Zhizi Compatibility (DZ) on alleviating heart injury cardiac ferroptosis in rats with myocardial infarction. Methods: A rat model infarction was established by ligation left anterior descending artery. The were equally randomly divided into 5 groups. sham group underwent open-chest surgery without arterial ligation, while other 4 groups surgery, including 3 treated low dose (4 g/kg/d), high (8 g/kg/d) DZ supplemented H-89 (0.5...