A5056622923- Congenital Heart Disease Studies
- Cardiovascular and Diving-Related Complications
- Aortic Disease and Treatment Approaches
- Coronary Artery Anomalies
- Tracheal and airway disorders
- Long-Term Effects of COVID-19
- COVID-19 Clinical Research Studies
- COVID-19 diagnosis using AI
- Congenital Diaphragmatic Hernia Studies
- Electrospun Nanofibers in Biomedical Applications
- Vascular Anomalies and Treatments
- Cardiac and Coronary Surgery Techniques
- Cardiac Valve Diseases and Treatments
- Kawasaki Disease and Coronary Complications
- Tissue Engineering and Regenerative Medicine
- Congenital Anomalies and Fetal Surgery
- Antiplatelet Therapy and Cardiovascular Diseases
- Hepatocellular Carcinoma Treatment and Prognosis
- Advanced Sensor and Energy Harvesting Materials
- Hydrogen embrittlement and corrosion behaviors in metals
- Pituitary Gland Disorders and Treatments
- Cardiac Structural Anomalies and Repair
- Mechanical Circulatory Support Devices
- Liver Disease and Transplantation
- Vascular anomalies and interventions
Guangdong Academy of Medical Sciences
2014-2024
Southern Medical University
2024
Guangdong Provincial People's Hospital
2019-2024
Ankang City Central Hospital
2020
Hubei University of Medicine
2020
Guangdong General Hospital
2014-2018
Brigham and Women's Hospital
2014
Harvard University
2014
Linkou Chang Gung Memorial Hospital
2014
Chang Gung University
2014
Abstract The mortality of coronavirus disease 2019 (COVID-19) differs between countries and regions. This study aimed to clarify the clinical characteristics imported second-generation cases in Shaanxi. included 134 COVID-19 Shaanxi outside Wuhan. Clinical data were compared severe non-severe cases. We further profiled dynamic laboratory findings some patients. In total, 34.3% patients cases, 11.2% had complications. As 7 March 2020, 91.8% discharged one patient (0.7%) died. Age, lymphocyte...
Abstract We evaluated the prevalence, image appearance, associated cardiovascular anomalies, and surgical outcomes of left pulmonary artery sling (LPAS) using computed tomography angiography (CCTA). A retrospective search patients from our database between October 2007 December 2014 identified 52,200 with congenital heart diseases (CHD) referred for CCTA, echocardiography, or magnetic resonance imaging. Clinical information, CCTA findings, were analyzed. showed a hospital-based prevalence 71...
The purpose of this study was to evaluate the prevalence, MDCT angiography (MDCTA) appearance, associated congenital cardiovascular abnormalities, and prognosis anomalous origin one pulmonary artery from aorta (AOPA) on basis MDCTA.We conducted a retrospective search patients with AOPA our database in single center, consisting 5729 referred for MDCTA known or suspected heart diseases transthoracic echocardiography. clinical information, subtypes AOPA, anomalies, surgical outcomes were...
Abstract Background The mortality of COVID-19 differs between countries and regions. By now, reports on are largely focused first-generation cases. This study aimed to clarify the clinical characteristics imported second-generation Methods retrospective, multicenter cohort included 134 confirmed cases from 9 cities outside Wuhan. Epidemiological, outcome data were extracted medical records compared severe non-severe We further profiled dynamic laboratory findings some patients. Results 34.3%...
Abstract Objective To evaluate the safety and feasibility of a modified poly( l ‐lactic acid) (PLLA) atrial septal defect (ASD) occluder. Methods Forty‐five piglets were divided into two groups: an experimental group ( n = 27) control 18). The underwent percutaneous implantation PLLA ASD device while widely used metal device. X‐ray imaging, transthoracic echocardiography (TTE), electrocardiogram (ECG), histopathology electron microscopic examination performed at 7 days, 1, 3, 6, 12 months...
The aim of this study is to evaluate the long-term effectiveness and safety a self-expandable, double-disk biodegradable device made poly-L-lactic acid (PLLA) for closure atrial septal defects (ASDs) in swine.ASDs were created by transseptal needle puncture followed balloon dilatation 20 piglets. experimental group comprised 18 animals, while remaining 2 animals used as controls. Effectiveness evaluated rectal temperature, leukocyte count, chest radiography, electrocardiogram, transthoracic...
Abstract Objective To evaluate the feasibility, safety, and effectiveness of a novel, absorbable atrial septal defect (ASD) closure device made poly‐ l ‐lactic acid (PLLA) in swine model ASD for first time humans. Methods A preclinical safety study was conducted using ASD. In clinical setting, five pediatric patients underwent with PLLA fluoroscopic transthoracic echocardiography guidance. The procedural results outcomes at 1 day, 30 days, 3 months, 6 months after were analyzed. Results 24‐...
Objectives: The aim of this study is to compare preoperative and postoperative conditions GMP-140 concentration, the aggregation activation platelets in congenital heart disease patients undergoing transcatheter closure atrial septal defects (ASDs) or ventricular (VSDs), appropriate dose aspirin after closure. Materials Methods: Thirty-two consecutive with ASD (n=16) VSD (n=16), as shown on transthoracic echocardiography right catheter examination, were treated a percutaneous occlusion....
Transcatheter closure of congenital coronary artery fistulas (CCAFs) is an alternative therapy to surgery; however, data regarding transcatheter for CCAF with a giant aneurysm (CAA) in pediatric patients are still limited due the rarity disease. We aimed evaluate efficacy and safety CAA population at single center.Medical records (<18 years old) who underwent between April 2007 September 2016 Guangdong Cardiovascular Institute (Guangdong, China) were reviewed.Twelve (median age, 6.1 years;...
Purpose: The clinical diagnosis of aorta coarctation (CoA) constitutes a challenge, which is usually tackled by applying the peak systolic pressure gradient (PSPG) method. Recent advances in computational fluid dynamics (CFD) have suggested that multi-detector computed tomography angiography (MDCTA)-based CFD can serve as non-invasive PSPG measurement. aim this study was to validate new method does not require any medical examination data other than MDCTA images for CoA. Materials and...
We reported the 3-year follow-up results of initial clinical experience with AbsnowTM device, a novel biodegradable occluder for percutaneous closure atrial septal defect (ASD).The device is total double-disc poly-L-lactic acid (PLLA) framework and PLLA membranes intergraded into to ensure its biodegradability, safety, efficacy.Five pediatric patients were enrolled from May June 2018 in our institution followed up 3 years. A evaluation transthoracic echocardiography performed at 24 hr, 1...
Abstract Background: The mortality of COVID-19 differs between countries and regions. By now, reports on are largely focused first-generation cases. This study aimed to clarify the clinical characteristics imported second-generation Methods : retrospective, multicenter cohort included 134 confirmed cases from 9 cities outside Wuhan. Epidemiological, outcome data were extracted medical records compared severe non-severe We further profiled dynamic laboratory findings some patients. Results...
Abstract Background The poly-L-lactic acid (PLLA) device is a novel, total biodegradable occluder dedicated to percutaneous closure of atrial septal defect (ASD) .Closure ASD with the PLLA has proven be relatively safe and effective in our preclinical first-in-human studies. Objective aim study was evaluate long-term safety efficacy large cohort patients. Methods A prospective enrolling patients who had clinically significant conducted institution from May 2018 August 2019. Percutaneous...
To evaluate the feasibility of applying AMPLATZER Vascular Plug Ⅱ (AVP Ⅱ) in transcatheter closure congenital coronary artery fistula children.Transcatheter procedure AVP was carried out 7 patients (3 males and 4 females, age 1.2-12.0 years) with between May 2014 September 2015 Pediatric Cardiology Department Guangdong Cardiovascular Institute. Selective angiography aortic root were performed after release device to immediate therapeutic effect. Echocardiography electrocardiography at 1 day,...
Abstract Background closure of atrial septal defect (ASD) has emerged as the treatment choice for majority defect. The biodegradable ASD device is a novel, absorbable made poly-L_latic acid (PLLA). This study evaluates feasibility, safety and effectiveness PLLA in swine model first time human. Objective reports on 24- 36- month follow-up results implanted first-in- man experience with 6-month follow-up. Method Preclinical was done model. In clinical setting, 5 pediatric patients secundum who...
Objective To make a comparison of transthoracic echocardiography(TTE) and cardiac multi-slice spiral computed tomography (MSCT) in the diagnosis partial anomalous pulmonary venous connection(PAPVC) children. Methods One hundred one patients admitted from February 2008 to April 2014 Guangdong General Hospital primarily diagnosed with PAPVC or without other congenital heart diseases were analyzed retrospectively, all cases underwent routine TTE, which 74 MSCT examination, TEE results...
Objective To monitor the degradation and bio-safety features of bioabsorbable iron-based stent planted in pig pulmonary artery. Methods A total 19 miniature pigs were randomly assigned into 3 groups.Three cases as control group; ten implantation group A with one implanted artery; other six B two stents artery.Follow-up studies for 24 months conducted all cases.Repeated measures ANOVA used to collect analyze statistical processing data at multiple time points...