A5055922518- Thyroid Cancer Diagnosis and Treatment
- Radiopharmaceutical Chemistry and Applications
- Prostate Cancer Treatment and Research
- Medical Imaging Techniques and Applications
- Immune Response and Inflammation
- Radiomics and Machine Learning in Medical Imaging
- Advanced MRI Techniques and Applications
- Lung Cancer Research Studies
- Cardiac Imaging and Diagnostics
- Lung Cancer Diagnosis and Treatment
- Coronary Artery Anomalies
- Acute Ischemic Stroke Management
- Coronary Interventions and Diagnostics
- Ureteral procedures and complications
- Hepatocellular Carcinoma Treatment and Prognosis
- MRI in cancer diagnosis
- Radiation Dose and Imaging
- Congenital Heart Disease Studies
- Cerebrovascular and Carotid Artery Diseases
- Gallbladder and Bile Duct Disorders
- Uterine Myomas and Treatments
- Tracheal and airway disorders
- Liver Disease Diagnosis and Treatment
- Total Knee Arthroplasty Outcomes
- Palliative Care and End-of-Life Issues
Zhejiang University
2020-2025
Sir Run Run Shaw Hospital
2024-2025
First Affiliated Hospital of Xi'an Jiaotong University
2022-2025
Second Hospital of Anhui Medical University
2024
Anhui Medical University
2024
China Medical University
2023
First Hospital of China Medical University
2023
Fujian Provincial Cancer Hospital
2023
Wuhan Children's Hospital
2023
EY Technologies (United States)
2022
Alhough antiangiogenic agents are the bedrock of treatment for radioiodine-refractory differentiated thyroid carcinoma (RAIR-DTC), novel with optimized features like greater target-binding affinities and more favorable pharmacokinetics profile needed. This phase II randomized, double-blind, placebo-controlled trial investigated efficacy safety anlotinib, a multikinase inhibitor, RAIR-DTC.Patients (ages between 18 70 years) pathologically confirmed locally advanced or metastatic RAIR-DTC were...
Chronological age (CA) is not a perfect proxy for the true biological aging status of body. A new measure, phenotypic (PhenoAge), has been shown to capture morbidity and mortality risk in general US population diverse subpopulations. This study was aimed at evaluating association between PhenoAge long-term outcome patients with multivessel coronary artery disease (CAD).A total 609 CAD who received PCI attempt follow-up were enrolled. The clinical all-cause on follow-up. calculated using an...
Previous studies reported that the aspartate aminotransferase (AST) to alanine (ALT) ratio (AST/ALT) was a risk factor in cardiovascular disease. Peripheral artery disease (PAD) is an important for death. However, only few investigated correlations between AST/ALT and PAD. We analyzed data from 10 900 patients with hypertension Chinese Hypertension Registry Study; 350 had PAD (prevalence 3.2%). After adjusting potential confounders, independently positively associated of (OR: 1.31, 95% CI,...
Abstract We evaluated the prevalence, image appearance, associated cardiovascular anomalies, and surgical outcomes of left pulmonary artery sling (LPAS) using computed tomography angiography (CCTA). A retrospective search patients from our database between October 2007 December 2014 identified 52,200 with congenital heart diseases (CHD) referred for CCTA, echocardiography, or magnetic resonance imaging. Clinical information, CCTA findings, were analyzed. showed a hospital-based prevalence 71...
Stroke is a common cardiovascular and cerebrovascular disease with high disability mortality. Lower educational attainment has been reported to be associated an increased risk of stroke, but it unclear which pathways mediate this association. Using genome-wide association studies (GWAS) based on European ancestry, we performed two-sample Mendelian randomization (MR) analyses investigate the causal genetically estimated stroke its subtypes. Then, used mediation assess extent seven...
The purpose of this study was to evaluate the feasibility using integrated slice-by-slice shimming (iShim) for improving image quality whole-body diffusion-weighted imaging (WBDWI) in patients with plasma disorder at 3 T by comparing WBDWI a conventional (3-dimensional [3D] shim) adjustment each body station.After approval local institutional review board, 2 healthy volunteers and 29 suspected participated cross-sectional study. All participants were scanned same protocol iShim 3D shim,...
Altered γ -aminobutyric acid (GABA), glutamate (Glu) levels, and an imbalance between GABAergic glutamatergic neurotransmissions have been involved in the pathophysiology of schizophrenia. However, it remains unclear how these abnormalities impact onset course psychosis. In present study, 21 drug-naïve subjects at ultrahigh risk for psychosis (UHR), 16 patients with first-episode schizophrenia (FES), 23 healthy controls (HC) were enrolled. vivo GABA glutamate+glutamine (Glx) levels medial...
The instantaneous wave-free ratio (iFR) closely related to fractional flow reserve (FFR) is a adenosine-independent physiologic index of coronary stenosis severity. We sought evaluate whether iFR derived from computed tomographic angiography (iFRCT) can be used as novel noninvasive method for diagnosis ischemia-causing stenosis. retrospectively enrolled 33 patients (47 lesions) with artery disease (CAD) and examined (CTA), invasive (ICA), FFR. Patient-specific anatomical model the was built...
The purpose of this study was to determine the prevalence unroofed coronary sinus (CS) syndrome at a tertiary hospital and analyze clinical information, cardiovascular CT angiography (CCTA) imaging findings, associated anomalies, surgical treatment identified cases.We retrospectively searched database for cases CS among patients who underwent CCTA known or suspected congenital heart disease. After determined, abnormalities, presence absence airway compression, outcome were recorded.A total...
Objective. The role of trimethylamine N-oxide (TMAO) in cardiovascular diseases has been highlighted. Nevertheless, the associations large-artery atherosclerotic (LAA) stroke with TMAO and blood lipid-related indices are little investigated. Methods. A cross-sectional comparative study was performed on 50 patients LAA healthy controls. Basic demographic data, common vascular risk factors, were collected. Plasma detected through liquid chromatography tandem mass spectrometry. Multivariable...
BackgroundAirway remodeling is an essential pathological basis of respiratory diseases such as asthma and COPD, which significantly related to pulmonary function clinical symptoms. And disease can be improved by regulating airway remodeling. This study aimed establish a knowledge map clarify current research hotspots future trends.MethodsA comprehensive search was performed analyze all relevant articles on using the Web Science Core Collection Database from January 01, 2004 June 03, 2023.2...
Panton–Valentine leukocidin (PVL) is associated with rare cases of necrotizing pneumonia that occur in otherwise healthy individuals. Human alveolar macrophages (HAMs) are major effector cells host defense against infections. However, the impact PVL on HAMs uncertain. We evaluated role cytotoxicity and production inflammatory cytokines secreted by HAMs. were purified from bronchoalveolar lavage fluid. Recombinant (rPVL) was used study to interfere HAM apoptosis cytokine vitro. Hoechst 33342...