A5102900644- Oral microbiology and periodontitis research
- Oral and Maxillofacial Pathology
- Hedgehog Signaling Pathway Studies
- Oral and gingival health research
- Immune Response and Inflammation
- Bone and Dental Protein Studies
- Bacterial biofilms and quorum sensing
- Gut microbiota and health
- Probiotics and Fermented Foods
- Heat Transfer and Optimization
- Tracheal and airway disorders
- Advanced MRI Techniques and Applications
- Salivary Gland Disorders and Functions
- Vascular Anomalies and Treatments
- Pulmonary Hypertension Research and Treatments
- IL-33, ST2, and ILC Pathways
- Cutaneous lymphoproliferative disorders research
- Dental materials and restorations
- Psoriasis: Treatment and Pathogenesis
- Dental Erosion and Treatment
- Laser Applications in Dentistry and Medicine
- Endodontics and Root Canal Treatments
- Natural product bioactivities and synthesis
- Microbial Metabolism and Applications
- Atomic and Subatomic Physics Research
Zunyi Medical University
2025
Nanjing University
2021-2024
North China University of Technology
2024
Wenzhou Medical University
2020
First Affiliated Hospital of Wenzhou Medical University
2020
Guangzhou Medical University
2014
Porphyromonas gingivalis (P. gingivalis) is a key pathogen of chronic periodontitis. Aryl hydrocarbon receptor (AhR) essential in immune homeostasis via modulation pro-inflammatory cytokines production and indoleamine 2,3-dioxygenase (IDO). In this study, it demonstrated that P. may regulate AhR signalling periodontitis, which provides potential target for further regulation studies Experimental periodontitis was induced C57BL/6 mice by silk ligature oral inoculation. The alveolar bone...
Human dental pulp stem cells (hDPSCs) have attracted tremendous attention in tissue regeneration engineering due to their excellent multidirectional differentiation potential. Photobiomodulation (PBM) using low-level light-emitting diodes (LEDs) or lasers has been proved promote the osteogenesis of mesenchymal cells. However, effect LEDs on osteogenic hDPSCs little published data. In this work, blue with different energy densities 2, 4, 6, 8, 10 J/cm2 was examined by vitro ALP staining,...
Hereditary gingival fibromatosis (HGF) is the most common genetic form of which featured as a localized or generalized overgrowth gingivae. Currently two genes (SOS1 and REST), well four loci (2p22.1, 2p23.3-p22.3, 5q13-q22, 11p15), have been identified associated with HGF in dominant inheritance pattern. Here, we report 13 individuals autosomal-dominant from four-generation Chinese family. Whole-exome sequencing followed by further co-segregation analysis was performed for family members...
As a chronic infectious disease, periodontitis can cause gum recession, loss of alveolar bone, loosening teeth, and even teeth. Dental plaque biofilm is the initiating factor for occurrence development periodontitis. Fusobacterium nucleatum (F. nucleatum) plays vital role in structure ecology dental biofilms. It bridge between early late colonization bacteria plaque. Understanding molecular mechanism F. during essential to control This study aimed determine gene expression profiles strain,...
Abstract Objective This study investigates the effects of ZNF862 on proliferation and apoptosis human gingival fibroblasts their related mechanisms. Background As a major transcription factor family, zinc finger proteins (ZFPs) regulate cell differentiation, growth, through conserved motifs, which allow high flexibility specificity in gene regulation. In our previous study, mutation was associated with hereditary fibromatosis. Nevertheless, little is known about biological function ZNF862....
Dentin hypersensitivity (DH) is a common oral disease with approximately 41.9% prevalence. Reconstruction of dental hard tissues the preferred treatment for relieving DH. Here, we applied biomineralization method using oligopeptide simulating cementum protein 1 (CEMP1) to regenerate on demineralized dentin.The self-assembly and property were detected by scanning electron microscopy (SEM), circular dichroism spectroscopy, transmission microscopy. Oligopeptide's binding capacity dentin was...
Background: Hemoptysis is a symptom of life-threatening condition.Bronchial artery embolization (BAE) recommended to control hemoptysis.However, non-bronchial systematic arteries (NBSAs) can be culprit vessels, particularly in recurrent hemoptysis patients after embolization, according recent studies.Therefore, the purpose present study was retrospectively assess risk factors with NBSA feeding interventional embolization.Methods: Between January 2014 and December 2017, total 545 underwent...
Pityriasis rubra pilaris (PRP)is a chronic,papulosquamous inflammatory skin disease characterized by keratotic follicular papules that confluence into scattered vast erythematous squamous plaques,palmoplantar keratoderma and scurf-like scales diffusely distributed on the scalp.It often develops erythroderma desquamativum.The pathogenesis of PRP is still unknown.At present,PRP considered to be mainly due heterozygous mutation in CARD14 gene chromosome 17q25.3 causes activation nuclear...
<title>Abstract</title> Periodontitis is a chronic inflammatory and immune reactive disease induced by the subgingival biofilm. The therapeutic effect for susceptible patients often unsatisfactory due to excessive response oxidative stress. Sinensetin (Sin) nature polymethoxylated flavonoid with anti-inflammatory antioxidant activities. Our study aimed explore beneficial of Sin on periodontitis specific molecular mechanisms. We found that attenuated stress levels periodontal ligament cells...