- Genomics, phytochemicals, and oxidative stress
- Chemotherapy-induced organ toxicity mitigation
- Drug-Induced Hepatotoxicity and Protection
- Nuclear Receptors and Signaling
- Liver Disease Diagnosis and Treatment
- Hormonal Regulation and Hypertension
- Neurological Complications and Syndromes
- COVID-19 Clinical Research Studies
- Liver physiology and pathology
- Acute Kidney Injury Research
- Coagulation, Bradykinin, Polyphosphates, and Angioedema
- Cancer Treatment and Pharmacology
- FOXO transcription factor regulation
- Heparin-Induced Thrombocytopenia and Thrombosis
- Pharmacological Effects and Toxicity Studies
- Pancreatitis Pathology and Treatment
- Hemophilia Treatment and Research
- Pregnancy and Medication Impact
- Dermatological and COVID-19 studies
- Blood Coagulation and Thrombosis Mechanisms
- Metal complexes synthesis and properties
- Immune Cell Function and Interaction
Nahda University
2014-2024
Liver malignancy is well recognized as a prominent health concern, with numerous treatment options available. Natural products are considered renewable source, providing inspiring chemical moieties that could be used for cancer treatment. Suaeda vermiculata Forssk has traditionally been employed management of hepatic conditions, including liver inflammation, and cirrhosis, to improve general function. The findings our earlier study demonstrated encouraging in vivo hepatoprotective benefits...
Abstract Activated factor X has a central role in the coagulation activation and also contributes to chronic inflammation tissue fibrosis. In this study, rivaroxaban, direct inhibitor, attenuates liver fibrosis induced by carbon tetrachloride (CCl 4 ). Male rats were randomly allocated into three groups: control group, CCl fibrotic +rivaroxaban (5 mg/kg) group. Liver was subcutaneous injection of twice week for 6 weeks. Rivaroxaban significantly restored biochemical parameter including...
Background Liver injury is a major health problem that challenges not only healthcare professionals but also the pharmaceutical industry and drug regulatory agencies.Continuous exposure to certain chemotherapeutic agents, drugs, environmental toxins, viral infections bacterial invasion within body can trigger liver eventually lead various diseases. Aim:The present investigation aims elucidate possible hepatoprotective effect of allopurinol on induced by administration single dose paracetamol...
Suaeda vermiculata Forssk. ex JF Gmel. (SV), a traditional known plant, has shown in vitro cytotoxic activity against HepG2 and HepG-2/ADR (doxorubicin-resistant cells) liver cell carcinoma lines, as well hepatoprotection paracetamol carbon tetrachloride (CCl4)-induced injury. The current study evaluated the protective effect of SV, administered N-diethylnitrosamine (NDEA)-induced HCC rats. possible modulatory SV on PI3K/HIF-1α/c-MYC/iNOS pathway was investigated. Sixty male adult albino...