A5022934334- Escherichia coli research studies
- Urinary Tract Infections Management
- Bacterial Genetics and Biotechnology
- Bacteriophages and microbial interactions
- Antibiotic Resistance in Bacteria
- Probiotics and Fermented Foods
- CRISPR and Genetic Engineering
- Gut microbiota and health
The University of Queensland
2022-2024
Extra-intestinal pathogenic Escherichia coli (ExPEC) belong to a critical priority group of antibiotic resistant pathogens. ExPEC establish gut reservoirs that seed infection the urinary tract and bloodstream, but mechanisms colonisation remain be properly understood. Ucl fimbriae are attachment organelles facilitate adherence. Here, we investigated cellular receptors for expression define molecular Ucl-mediated gut. We demonstrate differential in sequence types associated with disseminated...
ABSTRACT Complementation remains a foundation for demonstrating molecular Koch’s postulates. While this is frequently achieved using plasmids, limitations such as increased gene copy number and the need antibiotic supplementation to avoid plasmid loss can restrict their use. Chromosomal integration systems Tn 7 transposon provide an alternative plasmids complementation facilitate stable insertion of genes at chromosomal att site without selection pressure. Here, we enhanced utility mini-Tn...