A5034561733- Chromium effects and bioremediation
- Climate Change Communication and Perception
- Metalloenzymes and iron-sulfur proteins
- Amino Acid Enzymes and Metabolism
- Gut microbiota and health
- Infective Endocarditis Diagnosis and Management
- Chemical Reactions and Isotopes
- Probiotics and Fermented Foods
- Bacterial Infections and Vaccines
- Amoebic Infections and Treatments
- Science Education and Perceptions
- Escherichia coli research studies
- Animal and Plant Science Education
The University of Queensland
2022-2024
Australian National University
2011
Extra-intestinal pathogenic Escherichia coli (ExPEC) belong to a critical priority group of antibiotic resistant pathogens. ExPEC establish gut reservoirs that seed infection the urinary tract and bloodstream, but mechanisms colonisation remain be properly understood. Ucl fimbriae are attachment organelles facilitate adherence. Here, we investigated cellular receptors for expression define molecular Ucl-mediated gut. We demonstrate differential in sequence types associated with disseminated...
In this study, students and staff involved in an undergraduate science communication course investigated people's responses to a science-rich episode of the animated sitcom The Simpsons. Using focus groups, we sought find out if how influenced our 34 participants’ perceptions science, but results problematised very notion influence. People's varied widely, sometimes contradictory ways, from some participants seeing no at all others as ideological entire story. Participants’ discussions were...
Acquisition of the trace-element molybdenum via high-affinity ATP-binding cassette permease ModABC is essential for Pseudomonas aeruginosa respiration in anaerobic and microaerophilic environments. This study determined X-ray crystal structures molybdenum-recruiting solute-binding protein ModA from P. PAO1 metal-free state bound to group 6 metal oxyanions molybdate, tungstate, chromate. has a non-contiguous dual-hinged bilobal structure with single metal-binding site positioned between two...
Haemophilus influenzae is a commensal of the human upper respiratory tract that can infect diverse host niches due, at least in part, to its ability withstand both endogenous and host-mediated oxidative stresses. Here, we show hfeA, gene previously linked iron import, essential for H. manganese recruitment via HfeBCD transporter. Structural analyses metal binding HfeA uses unique mechanism involves substantial rotation C-terminal lobe protein. Disruption hfeA reduced acquisition was...