A5022104506- Health Systems, Economic Evaluations, Quality of Life
- Bladder and Urothelial Cancer Treatments
- Urinary and Genital Oncology Studies
- Cancer survivorship and care
- Cannabis and Cannabinoid Research
- Ethics in Clinical Research
- Meta-analysis and systematic reviews
- Family Support in Illness
- Multiple Myeloma Research and Treatments
- Urological Disorders and Treatments
- Endometrial and Cervical Cancer Treatments
- Palliative Care and End-of-Life Issues
- Parkinson's Disease Mechanisms and Treatments
- Misinformation and Its Impacts
- Colorectal Cancer Screening and Detection
- Tracheal and airway disorders
- Esophageal Cancer Research and Treatment
- Vaccine Coverage and Hesitancy
- Global Cancer Incidence and Screening
- Psychology of Moral and Emotional Judgment
- Multiple and Secondary Primary Cancers
- Patient-Provider Communication in Healthcare
- Child Nutrition and Feeding Issues
- COVID-19 and healthcare impacts
- Delphi Technique in Research
The University of Sydney
2017-2025
Chris O’Brien Lifehouse
2018
Abstract Background and objective Non-muscle invasive bladder cancer (NMIBC) is a chronic condition requiring frequent follow-up with endoscopic examinations, tumour resections intravesical treatments. In this clinical context, patient-reported outcomes (PROs) have enormous potential to inform treatment assessment recommendations for NMIBC. We aimed develop evaluate NMIBC Symptom Index (NMIBC-SI) facilitate research enhance care. Methods NMIBC-SI items were developed based on existing...
Aims Since 2016, more than one million new patients with chronic health conditions have been prescribed medicinal cannabis in Australia. We aimed to assess overall health-related quality of life (HRQL), pain, fatigue, sleep, anxiety, depression, and motor function a large real-world sample cannabis. previously found all patient-reported outcomes improved the first 3-months hypothesised that improvements would be maintained 12-months. Methods The QUEST Initiative, multicentre prospective...
Aims Patients with chronic health conditions not responding to conventional treatment can access medicinal cannabis (MC) prescriptions from clinicians in Australia. We aimed assess overall health-related quality of life (HRQL), pain, fatigue, sleep, anxiety, and depression a large real-world sample patients accessing prescribed cannabis. hypothesized that all patient-reported outcomes (PROs) would improve baseline 3-months. Methods The QUEST Initiative is prospective multicenter study any...
COVID-19 booster vaccinations have been recommended as a primary line of defence against serious illness and hospitalisation. This study identifies characterises distinct profiles attitudes towards vaccination, particularly the willingness to get dose. A sample 582 adults from Australia completed an online survey capturing COVID-related behaviours, beliefs range sociodemographic, psychological, political, social cultural variables. Latent Profile Analysis (LPA) identified three subgroups:...
Compare the health-related quality of life (HRQL) Australian general population during COVID-19 pandemic (2020) with pre-pandemic data (2015-2016) and identify pandemic-related demographic factors associated poorer HRQL.Participants were quota sampled from an online panel by four regions (defined active case numbers); then age sex. Participants completed survey about their HRQL [EORTC QLQ-C30 questionnaire General Health Question (GHQ)], characteristics, impact on daily life. scores compared...
To develop a value set reflecting the United States (US) general population's preferences for health states described by Functional Assessment of Cancer Therapy (FACT) eight-dimensions preference-based multi-attribute utility instrument (FACT-8D), derived from FACT-General cancer-specific health-related quality-of-life (HRQL) questionnaire. A US online panel was quota-sampled to achieve population sample representative sex, age (≥ 18 years), race and ethnicity. discrete choice experiment...
Objective Increasing uptake of cancer screening is a priority for health systems internationally, however, some patients may not attend because they are undergoing active treatment the interest or have other medical reasons that mean participation would be inappropriate. This study aims to quantify proportion non-participants who reason attending screening. Methods Medical participating in breast and bowel were defined priori on basis literature review expert opinion. The notes 700 at two GP...
Background: Nonmuscle invasive bladder cancer (NMIBC) is a chronic condition requiring intensive follow-up, repeated endoscopic examinations, tumor resections, and intravesical treatments that can occur every 3 months for life. In this clinical context, patient-reported outcomes (PROs) are critical concern patients their managing clinicians. PROs have enormous potential to be integral treatment assessment recommendations NMIBC; however, current PRO measures inadequate NMIBC because they lack...
Abstract Introduction Failure to incorporate key patient-reported outcome (PRO) content in trial protocols affects the quality and interpretability of collected data, contributing research waste. Our group developed evidence-based training specifically addressing PRO components protocols. We aimed assess whether 2-day educational workshops improved completeness against consensus-based minimum standards provided SPIRIT-PRO Extension 2018. Method Annual were conducted 2011–2017. Participants...
Evidence supports several countries introducing legislation to allow cannabis-based medicine as an adjunctive treatment for the symptomatic relief of chronic pain, chemotherapy-induced nausea, spasticity in multiple sclerosis (MS), epileptic seizures, depression, and anxiety. However, clinical trial participants do not represent entire spectrum disease health status seen patients currently accessing medicinal cannabis practice.This study aims collect real-world data evaluate health-related...
INTRODUCTION AND OBJECTIVE: Non-muscle invasive bladder cancer (NMIBC), a chronic condition, requires treatment and lifelong monitoring with regular endoscopic examinations. In this clinical context, symptom burden quality of life are important patient reported outcomes (PROs) for consideration when making decisions about treatment. Current PRO measures inadequately assess NMIBC-specific symptoms side effects contemporary treatments. This study aimed to develop patient-reported NMIBC Symptom...
Abstract IntroductionFailure to incorporate key patient-reported outcome (PRO) content in trial protocols affects the quality and interpretability of collected data, contributing research waste. Our group developed evidence-based training specifically addressing PRO components protocols. We aimed assess whether 2-day educational workshops improved completeness against consensus-based minimum standards provided SPIRIT-PRO Extension 2018.MethodAnnual were conducted 2011–2017. Participants...