A5020436027- Cholangiocarcinoma and Gallbladder Cancer Studies
- Cancer Research and Treatments
- Ultrasound and Hyperthermia Applications
- Nanoplatforms for cancer theranostics
- Pancreatic and Hepatic Oncology Research
- Viral-associated cancers and disorders
- Cancer-related molecular mechanisms research
- Glioma Diagnosis and Treatment
- Multiple and Secondary Primary Cancers
- Cytokine Signaling Pathways and Interactions
- Cytomegalovirus and herpesvirus research
- Cancer, Lipids, and Metabolism
- Flavonoids in Medical Research
- Lung Cancer Diagnosis and Treatment
- Cancer, Hypoxia, and Metabolism
- Pharmacological Effects of Natural Compounds
- Metabolomics and Mass Spectrometry Studies
- Gastric Cancer Management and Outcomes
The Third Affiliated Hospital of Zhejiang Chinese Medical University
2024
Hangzhou Cancer Hospital
2022-2024
Second Affiliated Hospital of Zhejiang University
2023
Zhejiang University
2023
ABSTRACT Radiation resistance is a crucial factor influencing therapeutic outcomes in colorectal cancer (CRC). Baicalein (BE), primarily derived from Scutellaria baicalensis , has demonstrated anti‐CRC properties. However, the impact of BE on radiosensitivity CRC remains unclear. This study aimed to evaluate radiosensitization effects and elucidate its mechanism radiotherapy. We established an vitro radioresistant cell model (CT26‐R) using parental cells (CT26) subjected ionizing radiation...
Glioblastoma (GBM) is the most common intracranial tumor with characteristic of malignancy. Resveratrol, a natural originated polyphenolic compound, has been reported to act as potential radiosensitizer in cancer therapy. Magnetic resonance imaging (MRI) first choice for diagnosis, pathological grading, and efficacy evaluation GBM. In this study, MRI was applied observe whether resveratrol could intensify anti-GBM effect by enhancing antitumor immunity during radiotherapy. We established an...
Focused ultrasound (FUS) is a non-invasive tumor therapy technology emerging in recent years, which can treat various solid tumors. However, it unclear whether FUS affect the pyroptosis of colon cancer (CC) cells. Here, we analyzed effect on orthotopic CC model.After an mouse model was constructed by injecting CT26-Luc cells, BABL/C mice were allocated to normal, tumor, FUS, and + BAY11-7082 (pyroptosis inhibitor) groups. We monitored status through vivo fluorescence image analysis. The...
Colon cancer (CC) is a malignancy of the digestive tract, and computed tomography (CT)-guided radiofrequency ablation (RFA) has been extensively adopted in treatment. We aimed to explore changes fecal metabolism after CT-guided RFA CC mice. The orthotopic mice received upon modeling. Subsequently, we quantified tumor volumes weights assess treatment efficacy. Next, because metabolomics useful for evaluating therapeutic validity, feces were collected analysis. inhibited growth effectively....
To develop and validate a diagnostic scoring system to differentiate intrahepatic mass-forming cholangiocarcinoma (IMCC) from solitary colorectal liver metastasis (CRLM).A total of 366 patients (263 in the training cohort, 103 validation cohort) who underwent MRI examination with pathologically proven either IMCC or CRLM two centers were included. Twenty-eight features collected. Univariate analyses multivariate logistic regression performed identify independent predictors for distinguishing...
Colon cancer (CC) is the main fatal disease of humans. Microwave hyperthermia (MH) an adjuvant therapy for diverse cancers. Tumor necrosis factor-α induced protein-8-like 2 (TIPE2) a tumor suppressor. However, effect MH combined with TIPE2 on CC remains unclear.
Objective This study was conducted to investigate the imaging information, laboratory data, and clinical characteristics of duodenal papillary malignancies, aiming contribute early diagnosis these diseases. Methods The characteristics, computed tomography (CT) findings 17 patients with adenoma major papilla (the group) 58 cancer were retrospectively analyzed. measurement data analyzed using t test expressed as mean ± standard deviation. counting χ 2 in n (%). Pearson correlation analysis...
Objective: To investigate the computed tomography (CT) findings of chronic duodenal papilla mucositis and papillary carcinoma, provide more imaging information for early diagnosis malignant diseases.Methods: CT clinical data 40 patients with 46 carcinoma were retrospectively analyzed. Observation measuring direct signs (including size, shape, density, enhancement uniformity, etc.), indirect pancreaticobiliary dilatation) indicators tumor markers CA19-9, CA125, CEA, blood routine white cell...