A5101701759- Meat and Animal Product Quality
- Polysaccharides and Plant Cell Walls
- Proteins in Food Systems
- Microbial Metabolites in Food Biotechnology
- Biochemical effects in animals
- Cancer Research and Treatments
- Food composition and properties
- Ultrasound and Hyperthermia Applications
- Polysaccharides Composition and Applications
- Advanced Cellulose Research Studies
- Electrochemical sensors and biosensors
- PI3K/AKT/mTOR signaling in cancer
- Protein Tyrosine Phosphatases
- Lung Cancer Diagnosis and Treatment
- Animal Nutrition and Physiology
- Protein Interaction Studies and Fluorescence Analysis
- Microbial Metabolic Engineering and Bioproduction
- Glycosylation and Glycoproteins Research
- Advances in Cucurbitaceae Research
- Muscle metabolism and nutrition
- Collagen: Extraction and Characterization
- Cancer, Hypoxia, and Metabolism
- Insect Utilization and Effects
- Ionic liquids properties and applications
- Plant-Microbe Interactions and Immunity
Jiangsu University
2021-2025
Wuhan Polytechnic University
2022-2025
Hangzhou Cancer Hospital
2021-2024
Hubei University of Medicine
2019-2023
Zhejiang University
2021-2023
Southwest University
2019-2020
In this study, the influence of multi-frequency ultrasound irradiation on functional properties and structural characteristics gluten, as well textural cooking noodles were investigated. Results showed that contain less gluten pretreated by ultrasonic frequency dependent. Moreover, a smaller amount sonicated could achieve quality commercial noodles. There was no significant difference in texture between with 12%, 11%, 10% single-frequency (40 kHz), dual-frequency (28/40 triple-frequency...
Non-small cell lung cancer (NSCLC) patients carrying an epidermal growth factor receptor (EGFR) mutation are initially sensitive to EGFR-tyrosine kinase inhibitors (TKIs) treatment, but soon develop acquired resistance. The treatment effect of EGFR-TKIs-resistant NSCLC still faces challenges. Cucurbitacin B (CuB), a triterpene hydrocarbon compound isolated from plants various families and genera, elicits anticancer effects in variety types. However, whether CuB is viable option for...
In whole grains, phenolics are covalently bound to cell-wall dietary fibers, forming nonextractable phenolics. Enhancing the release of has garnered significant attention improve nutritional value grains. Our findings revealed that fermentation raw barley fiber with Lactiplantibacillus plantarum dy-1 led a decrease 2408.69 μg/g in We identified 6-phospho-β-glucosidase responsible for this process through proteomic analysis, which was increased more than 4 times during and conducted...
Alkylimidazolium-based ionic liquids (AILs), once hailed as ″green solvents,″ have seen widespread use, but recent concerns emerged regarding their environmental and health risks. This study integrates in vitro vivo dose-response metabolomics to investigate liver metabolic disturbances pathway sensitivity 1-octyl-3-methylimidazolium (M8OI) exposure. Important function indicators, including catalase, alanine aminotransferase, aspartate glycosylated serum protein, showed significant...
Discoloration of red peppers, such as fading and color desaturation, can occur during harvesting, drying storage. In this study, liquid chromatography-mass spectrometry (LC-MS) was used to identify quantify carotenoids. Metabolomics analysis based on ultra-high performance chromatography coupled with a quadrupole extractive orbitrap mass spectrometery (UHPLC-QE Orbitrap/MS) performed determine the metabolites present in discolored peppers normal peppers. This approach showed that carotenoid...
Per- and polyfluoroalkyl substances (PFASs) are a novel class of emerging persistent organic pollutants (POPs) owing to their environmental persistence bioaccumulation. Red swamp crayfish is major source exposure PFASs, while the dietary intake PFASs from still unclear. We investigated concentrations in 130 batches 100 samples Middle Lower Reaches Yangtze River Delta. Seven Perfluoroalkyl carboxylic acids (PFCAs), 3 sulfonates (PFSAs), 6:2 Cl-PFESA were analyzed by ultra-high performance...
Circular RNAs (circRNAs) play vital regulatory roles in the development of ovarian cancer (OC). However, functions circRNA Atlastin GTPase 2 (circATL2) paclitaxel (PTX) resistance OC are still unclear. As a result, circATL2 was upregulated PTX-resistant tissues and cells. CircATL2 knockdown reduced IC50 PTX, inhibited colony formation ability promoted cell cycle arrest apoptosis Silencing restrained PTX vivo. Furthermore, miR-506-3p could be targeted by inhibition reversed impacts on...
The purpose of this study was to determine the effect pre-rigor salting on quality characteristics surimi gels prepared from snakehead fish muscle. Pre-rigor and post-rigor muscle were mixed with 0.3% or 3% NaCl (w/w) made into gels, respectively. Results showed that had a higher content ATP, longer sarcomere, pH greater protein solubility. Metabolic profile revealed antioxidants such as butyryl-L-carnitine. Transmission electron microscopy more damage mitochondria in Surimi paste meat...
Ionic liquids (ILs), traditionally considered environmentally benign solvents, have shown potential toxicity to organisms, raising concerns about their safety. Among them, 1-octyl-3-methylimidazolium (M8OI) has been detected at high concentrations in soils and exhibits hepatotoxic properties. To uncover the molecular mechanisms underlying this toxicity, whole-transcriptome sequencing was performed, coupled with benchmark dose (BMD) modeling, derive transcriptomic points-of-departure (tPOD)...
Focused ultrasound (FUS) is a non-invasive tumor therapy technology emerging in recent years, which can treat various solid tumors. However, it unclear whether FUS affect the pyroptosis of colon cancer (CC) cells. Here, we analyzed effect on orthotopic CC model.After an mouse model was constructed by injecting CT26-Luc cells, BABL/C mice were allocated to normal, tumor, FUS, and + BAY11-7082 (pyroptosis inhibitor) groups. We monitored status through vivo fluorescence image analysis. The...
Colon cancer (CC) is a malignancy of the digestive tract, and computed tomography (CT)-guided radiofrequency ablation (RFA) has been extensively adopted in treatment. We aimed to explore changes fecal metabolism after CT-guided RFA CC mice. The orthotopic mice received upon modeling. Subsequently, we quantified tumor volumes weights assess treatment efficacy. Next, because metabolomics useful for evaluating therapeutic validity, feces were collected analysis. inhibited growth effectively....
Colon cancer (CC) is the main fatal disease of humans. Microwave hyperthermia (MH) an adjuvant therapy for diverse cancers. Tumor necrosis factor-α induced protein-8-like 2 (TIPE2) a tumor suppressor. However, effect MH combined with TIPE2 on CC remains unclear.