- Cancer-related molecular mechanisms research
- Plant Pathogens and Fungal Diseases
- GABA and Rice Research
- Biological and pharmacological studies of plants
- Gene expression and cancer classification
- Histone Deacetylase Inhibitors Research
- Microbial Metabolic Engineering and Bioproduction
- Biocrusts and Microbial Ecology
- Eosinophilic Esophagitis
- Plant responses to water stress
- Cancer Mechanisms and Therapy
- Photosynthetic Processes and Mechanisms
- Brain Metastases and Treatment
- Cancer Research and Treatments
- Nuclear Receptors and Signaling
- Enzyme Structure and Function
- MicroRNA in disease regulation
- Ginseng Biological Effects and Applications
- Hedgehog Signaling Pathway Studies
- Mass Spectrometry Techniques and Applications
- Advanced Chemical Sensor Technologies
- Algal biology and biofuel production
- Gut microbiota and health
- Process Optimization and Integration
- IL-33, ST2, and ILC Pathways
Southwest Forestry University
2025
First Affiliated Hospital of GuangXi Medical University
2019-2024
Guangxi Medical University
2019-2024
Tumor Hospital of Guangxi Medical University
2024
Wenzhou Medical University
2023
Beijing University of Chinese Medicine
2022
Shandong University of Traditional Chinese Medicine
2020
Putian University
2019
University of Pennsylvania
2018
Optica
2018
Sepsis-induced liver injury (SILI) is an important cause of septicemia deaths. BaWeiBaiDuSan (BWBDS) was extracted from a formula Panax ginseng C. A. Meyer, Lilium brownie F. E. Brown ex Miellez var. viridulum Baker, Polygonatum sibiricum Delar. Redoute, Lonicera japonica Thunb., Hippophae rhamnoides Linn., Amygdalus Communis Vas, Platycodon grandiflorus (Jacq.) DC., and Cortex Phelloderdri. Herein, we investigated whether the BWBDS treatment could reverse SILI by mechanism modulating gut...
Abstract Accumulating studies have recognized microRNAs (miRs) and long noncoding RNAs (lncRNAs) as important molecules involved in the mediation of various biological processes, including innate immunity. In this study, we investigated a novel RNA regulatory circuitry immunity during sepsis. A cecal ligation puncture‐induced sepsis mouse model was established to determine expression mast cell membrane protein 1 (MCEMP1). The crosstalk among lncRNA nuclear enriched abundant transcript...
Tuber rot caused by Fusarium cugenangense is a serious problem in the cultivation and post-harvest preservation of Gastrodia. It essential to explore effective biocontrol methods control this disease. In work, we investigated efficiency defense responses an endophytic Streptomyces globisporus strain WB03 isolated from coralloid roots Cycas panzhihuaensis against Gastrodia tuber S. can secrete extracellular hydrolases that produce active compounds. Treatment with damaged cell membranes F....
Antiglioma effects of cytarabine on leptomeningeal metastasis high-grade glioma by targeting the PI3K/Akt/mTOR pathway Kai-Hong Zhao,1 Can Zhang,2 Yue Bai,1 Yan Li,1 Xun Kang,1 Jian-Xin Chen,1 Kun Yao,3 Tao Jiang,4 Xiao-Song Zhong,2 Wen-Bin Li1 1Department Glioma, 2Clinical Center Gene And Cell Engineering, Beijing Shijitan Hospital, 3Department Neurosurgery, Tiantan 4Department Pathology, Sanbo Brain Capital Medical University, Beijing, People’s Republic China Abstract: Leptomeningeal...
Investigating the interaction between Mast cells (MCs) and Mononuclear Phagocytes (MPs) in tumor microenvironment (TME) of blader cancer (BCa) to uncover potential immunotherapeutic targets.
We employ site-specific, linear and nonlinear infrared spectroscopic techniques as well fluorescence spectroscopy molecular dynamics simulations to investigate the binding interactions of urea three its derivatives, methylurea, 1,3-dimethylurea, tetramethylurea, with protein aromatic polar side chains. find that (1) methylation leads preferential between cosolvent molecules chains an affinity increases number methyl groups; (2) tetramethylurea cause significant dehydration effect is most...
Cancers harboring serine threonine kinase (STK11) alteration or SWI/SNF-related, matrix-associated, actin-dependent regulator of chromatin, subfamily B, member 1 (SMARCB1) mutation are conventionally considered as treatment-refractory to immune checkpoint inhibitors chemotherapy, respectively. However in the present report, we demonstrated a case dedifferentiated non-small cell lung cancer, characterized by STK11 loss (due promoter loss) co-mutated with SMARCB1 deficiency mutation, has...