A5029075422- Cystic Fibrosis Research Advances
- Chronic Obstructive Pulmonary Disease (COPD) Research
- Asthma and respiratory diseases
- Neonatal Respiratory Health Research
- Respiratory Support and Mechanisms
- Respiratory and Cough-Related Research
- Tracheal and airway disorders
- Pediatric health and respiratory diseases
- DNA Repair Mechanisms
- Congenital Heart Disease Studies
- Congenital Diaphragmatic Hernia Studies
- Transplantation: Methods and Outcomes
- Pleural and Pulmonary Diseases
- Neuroscience of respiration and sleep
- Genetic Neurodegenerative Diseases
- Parasitic infections in humans and animals
- Body Composition Measurement Techniques
- Interstitial Lung Diseases and Idiopathic Pulmonary Fibrosis
- Inhalation and Respiratory Drug Delivery
- Esophageal and GI Pathology
- Mitochondrial Function and Pathology
- Occupational and environmental lung diseases
- Respiratory viral infections research
- Textile materials and evaluations
- Pneumothorax, Barotrauma, Emphysema
Technion – Israel Institute of Technology
2007-2025
Montefiore Medical Center
2025
Rebecca Sieff Hospital
2025
Tel Aviv Sourasky Medical Center
2024-2025
Edmond and Lily Safra Children's Hospital
2011-2021
Sheba Medical Center
2011-2021
Tel Aviv University
2010-2021
Rambam Health Care Campus
2015-2016
Pulmonary Associates
2016
Meyer Children's Hospital
2005-2015
Advances in spirometry measurement techniques have made it possible to obtain measurements children as young 3 years of age; however, practice, application remains limited by the lack appropriate reference data for children, which are often based on population-specific samples.We aimed build previous models collating existing (aged 3-7 yr), produce updated prediction equations that span preschool and also linked established older adults.The Asthma UK Collaborative Initiative was collate lung...
Abstract The treatment of infants aged 1.5–11.0 months suffering from acute bronchiolitis with a combination inhaled albuterol and systemic corticosteroids or placebo was compared in 50 double blind study. mean initial clinical score the rate improvement similar two groups. ± SD hospital stay 5.0 1.2 days for steroid group 5.2 1.7 group. Lung function measured 14 (7 each group) showed evidence increased lung volumes severe airway obstruction stage (the values were: TGV, 31 mL/kg; SGaw, 0.104...
Abstract Objective Probiotics reduce intestinal inflammation in, and Lactobacillus GG (LGG) reduces pulmonary exacerbation rate cystic fibrosis (CF) patients. We intended to determine the effect of a mixed probiotic preparation on exacerbations inflammatory characteristics sputum in CF Study Design A prospective pilot study 10 patients with mild–moderate lung disease Pseudomonas aeruginosa colonization, treated probiotics for 6 months. Pulmonary function tests (PFT's), cultures...
Although airway disease in preschool children is common, standard spirometry limited by the level of cooperation. We evaluated a computer-animated system (SpiroGame) aimed at improving children's performance spirometry. SpiroGame includes commercial pneumotachograph (ZAN100; ZAN Messgeraete GmbH, Oberthulba, Germany) and games teaching tidal breathing all steps an FVC maneuver. was compared with flow-targeted candle-blowing software (MasterLab, Jaeger, Germany), extrapolated predicted...
Objective: The use of flexible bronchoscopy (FOB) and bronchoalveolar lavage (BAL) in investigating pediatric patient with airway abnormalities pulmonary infiltrates are indispensable now a routine procedure many centers. Immunocompromised cancer patients, especially after bone marrow transplantation, children who have undergone surgery for congenital heart disease (CHD) at high risk disease. Our aim was to study the diagnostic rate, safety, clinical yield FOB critically ill patients....
Introduction Pediatric respiratory monitoring, crucial for assessing children's health, particularly those with diseases, often relies on invasive or cumbersome methods. Here, we propose a non-invasive approach using video depth camera to measure breathing parameters in children, offering innovation and promise. Aims We aim introduce validate straightforward remote procedure measuring children. These include rate (RR), volumetric changes during inhalation exhalation, the phase angle (PA)...
Liver disease is the second cause of death in cystic fibrosis. The most deleterious complication liver portal hypertension, which has an estimated prevalence up to 8%. Portal hypertension may manifest itself by splenomegaly, hypersplenism, gastro-oesophageal bleeding and ascites. aim our study was determine prevalence, risk factors invasive management at centre.One hundred fifty patients with fibrosis were followed between 1975 2000 national centre Israel. Forty (27%) had disease. All...
ABSTRACT Objectives: Patients with cystic fibrosis (CF) presenting meconium ileus (MI) tend to have worse outcomes than those without MI. We evaluated the clinical characteristics and survival rates among Israeli patients CF MI after a prolonged follow‐up (15–30 years). Methods: A multicenter retrospective study. Forty‐nine CF, representing 13.8% of all in Israel, presented (current age 17.4 ± 7.9 years) between 1975 2006. They were compared 38 19.3 6.5 matched by sex transmembrane...
Abstract Introduction Lung disease is a significant cause of the short life span ataxia telangiectasia (A‐T) patients. Objective lung function measurements are difficult to achieve in A‐T. Aim To assess by spirometry relation clinical characteristics A‐T patients followed up at Israeli Ataxia Telangiectasia National Clinic. Patients and Methods Medical data were collected from 27 during 2004–2007. Laboratory, nutritional condition, mode treatment, pulmonary status, malignancies assessed. The...
Abstract Background Measurement of FRC in whole body plethysmography (FRCpleth) is not performed young children (aged 3–5 years) because it involves sitting alone a closed box and breathing attempts against occlusion. Objective To assess the feasibility measuring FRCpleth children. Methods Results Seventy‐one 102 (age range 3.3–6.9 spirometry measurements. Twenty‐six had controlled asthma (Group‐A); 26 were tested during exacerbation uncontrolled (Group‐UA), 19 after receiving chemotherapy...
Airways obstruction and lung volume restriction, major features of disease in cystic fibrosis (CF), may regress independently, causing dysanapsis between these parameters.To explore the significance (FEF(25-75)/FVC) ratio CF.Yearly best spirometry data, collected during 8.6 ± 1 year per patient, was determined from 93 patients with CF. Three groups were formed according to initial FEV(1). Group-N (n = 35; control, FEV(1) above 80%predicted); Group-B 38; below 80% predicted); Group-LT 20;...
During breathing under sedation via a two-way valve, airflow (V), volume (delta V), and airway pressure (P) were recorded in eight normal (N) infants, seven with reversible obstructive disease (ROAD), chronic lung (CLD). Intermittently, expiratory clamping (EVC) was applied, involving selective occlusion of the valve for three to five breaths. The latter produced cumulative increases delta V that, due progressive recruitment Hering-Breuer reflex, accompanied by increasing plateaus P (i.e.,...