A5101595142- Extracellular vesicles in disease
- Neurogenesis and neuroplasticity mechanisms
- Circular RNAs in diseases
- MicroRNA in disease regulation
- Atomic and Subatomic Physics Research
- Quantum, superfluid, helium dynamics
- Advanced NMR Techniques and Applications
- NMR spectroscopy and applications
- Chemokine receptors and signaling
- HIV/AIDS Research and Interventions
- Pluripotent Stem Cells Research
- Advanced biosensing and bioanalysis techniques
- DNA and Biological Computing
- Atherosclerosis and Cardiovascular Diseases
- Cytomegalovirus and herpesvirus research
- Immune cells in cancer
- Photoacoustic and Ultrasonic Imaging
- Neuroblastoma Research and Treatments
- Nuclear Receptors and Signaling
- Advanced Memory and Neural Computing
- ATP Synthase and ATPases Research
- Multiple Myeloma Research and Treatments
- Angiogenesis and VEGF in Cancer
- Optical Coherence Tomography Applications
- Phagocytosis and Immune Regulation
Shandong Normal University
2024
Tongji University
2008-2022
Shanghai Tenth People's Hospital
2015-2022
Jinan University
2022
Institute of Solid State Physics
2008-2009
Forschungszentrum Jülich
2008-2009
Stadtwerke Jülich (Germany)
2009
Abstract Angiogenesis is the process by which new vessels form from existing vascular networks. Human umbilical vein endothelial cells (HUVECs) may contribute to study of repair and angiogenesis. The chemokine CXCL12 regulates multiple cell functions, including angiogenesis, mainly through its receptor CXCR4. In contrast CXCL12/CXCR4, few studies have described roles for CXCR7 in biology, downstream mechanism angiogenesis remains unclear. results present showed that dose-dependently enhanced...
Abstract Background Glioblastomas are lethal brain tumors under the current combinatorial therapeutic strategy that includes surgery, chemo- and radio-therapies. Extensive changes in tumor microenvironment is a key reason for resistance to or radio-therapy frequent recurrences. Understanding tumor-nontumor cell interaction TME critical developing new therapy. known recruit normal cells their environs sustain growth encroachment into other regions. Neural progenitor (NPCs) have been noted...
The application of combination antiretroviral therapy has greatly reduced the death rate from AIDS. However, up to 50% patients on develop HIV-associated neurocognitive disorders (HAND), which is associated with residual neuroinflammation and oxidative injury in brain. Neural stem cells (NSCs) progenitors play a vital role repairing neuronal injuries. Therefore, we hypothesize that may adversely affect NSCs/progenitors, contributing increasing prevalence HAND. Here, show combined medication...
Cell cycle regulation of neural progenitor cells (NPCs) is an essential process for neurogenesis, development, and repair after brain trauma. Stromal cell-derived factor-1 (SDF-1, CXCL12) its receptors CXCR4 CXCR7 are well known in regulating the migration survival NPCs. The effects CXCL12 on NPCs proliferation, cell regulation, their associated signaling pathways remain unclear. Cyclin D1 a protein required progression through G1 phase downstream target β -catenin. Therefore, cyclin plays...
Fourier single-pixel imaging (FSI) allows an image to be reconstructed by acquiring the spectrum of using a detector. Fast FSI is typically achieved truncated spectrum, that is, only low-frequency coefficients are acquired, with high-frequency discarded. However, truncation leads undesirable ringing artifacts in resulting image. Ringing produce false edges and reduce contrast, quality degeneration. The artifact particularly severe dynamic FSI, where sampling ratio generally ultra-low. We...
Alzheimer’s disease (AD) is a prominent form of dementia, characterized by aggregation the amyloid β-peptide (Aβ) plaques and neurofibrillary tangles, loss synapses neurons, degeneration cognitive functions. Currently, although variety medications can relieve some symptoms, there no cure for AD. Recent breakthroughs in stem cell field provide promising strategies AD treatment. Stem cells including embryonic (ESCs), neural (NSCs), mesenchymal (MSCs), induced pluripotent (iPSCs) are potentials...
High-resolution low-field nuclear magnetic resonance (NMR) signals of selected liquid samples were recorded using a nitrogen-cooled superconducting quantum interference device (SQUID). The NMR measurements performed at Larmor frequencies ( <i xmlns:mml="http://www.w3.org/1998/Math/MathML" xmlns:xlink="http://www.w3.org/1999/xlink">f</i> <sub xmlns:xlink="http://www.w3.org/1999/xlink">L</sub> ) from 2 Hz to 40 kHz. natural spectral linewidth tap water could be measured in fields below 7...
Abstract Endothelial injuries, including cell pyroptosis, are ongoing inflammatory processes with key roles in atherosclerosis development. Our previous report showed that the chemokine CXCL12 and its receptor CXCR7 associated proliferation angiogenesis of endothelial cells. Nevertheless, mechanism underlying these effects on atherosclerotic lesions, especially dysfunction, remains unknown. Here, we demonstrated was upregulated human carotid plaques, apolipoprotein E knockout (ApoE −/− )...
Under the highly homogeneous Earth's magnetic field (EMF), nuclear resonance experiments were performed utilizing a nitrogen-cooled superconducting quantum interference device (SQUID). The Larmor frequency fL of protons is around 2060 Hz in our environment. sensitivity SQUID magnetometer EMF reached about 70 fT/√Hz near this fL. Free induction decay curves obtained with high signal-to-noise ratio. amplitude NMR signal agreed theoretical value. 1H spectra some samples, for instance, tap...
This data article contains three figures and videos related to the research entitled "Applications of Stripe Assay in Study CXCL12-mediated Neural Progenitor Cell Migration Polarization" Zhang et al. (2015) [1], which uses stripe assay study mouse neural progenitor cell (NPC) migration polarization. The current describes neurosphere method used culture NPCs. NPCs neurospheres monolayer were characterized using immunocytochemistry with antibodies against two classic NPC markers: nestin SOX2....
Abstract Background Glioblastomas are lethal brain tumors under the current combinatorial therapeutic strategy that includes surgery, chemo- and radio-therapies. Extensive changes in tumor microenvironment is a key reason for resistance to or radio-therapy frequent recurrences. Understanding tumor-nontumor cell interaction TME critical developing new therapy. known recruit normal cells their environs sustain growth encroachment into other regions. Neural progenitor (NPCs) have been noted...