Zhen Yang

ORCID: 0000-0003-0806-6517
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About
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Research Areas
  • Functional Brain Connectivity Studies
  • Neural dynamics and brain function
  • Advanced Neuroimaging Techniques and Applications
  • Crystallization and Solubility Studies
  • X-ray Diffraction in Crystallography
  • Hemodynamic Monitoring and Therapy
  • Cardiovascular Health and Disease Prevention
  • Vestibular and auditory disorders
  • Advanced MRI Techniques and Applications
  • Mental Health Research Topics
  • Non-Invasive Vital Sign Monitoring
  • Liver Disease and Transplantation
  • Heart Rate Variability and Autonomic Control
  • Genetic Neurodegenerative Diseases
  • Liver Disease Diagnosis and Treatment
  • Cardiac Arrest and Resuscitation
  • Crystallography and molecular interactions
  • Fetal and Pediatric Neurological Disorders
  • Ultrasound in Clinical Applications
  • Respiratory Support and Mechanisms
  • EEG and Brain-Computer Interfaces
  • Child Abuse and Trauma
  • Sulfur-Based Synthesis Techniques
  • Stress Responses and Cortisol
  • Thermal Regulation in Medicine

Ludong University
2025

Shandong Normal University
2024

Xiangya Hospital Central South University
2024

Central South University
2024

Tianjin University of Traditional Chinese Medicine
2024

University of Toronto
2024

Shaanxi Provincial People's Hospital
2021-2024

Shanxi Medical University
2021-2024

Zaozhuang University
2023

Johns Hopkins University
2012-2022

See King et al. (doi:10.1093/aww348) for a scientific commentary on this article. Detailed mapping of clinical dysfunctions to the cerebellar lobules in disease populations is necessary establish functional significance implicated cognitive and motor functions normal subjects. This study constitutes first quantitative examination lobular correlates broad range phenomena disease. We analysed cross-sectional data from 72 cases with 36 controls without Cerebellar lobule volumes were derived...

10.1093/brain/aww327 article EN Brain 2016-11-20

Both major depressive disorder (MDD) and post-traumatic stress (PTSD) are characterized by alterations in intrinsic functional connectivity. Here we investigated changes connectivity across these disorders as a function of cognitive behavioral therapy (CBT), an effective treatment both disorders. 53 unmedicated right-handed participants were included longitudinal study. Patients diagnosed with PTSD (n = 18) MDD 17) structured diagnostic interview treated 12 sessions manualized CBT over...

10.1016/j.nicl.2017.01.030 article EN cc-by-nc-nd NeuroImage Clinical 2017-01-01

Abstract Caregiver maltreatment induces vulnerability to later-life psychopathology. Clinical and preclinical evidence suggest changes in prefrontal limbic circuitry underlie this susceptibility. We examined question using a rat model of maternal methods translated from humans, resting-state functional magnetic resonance imaging (R-fMRI). Rat pups were reared by mothers provided with insufficient or abundant bedding for nest building postnatal (PN) days 8 12 underwent behavioral assessments...

10.1038/tp.2016.276 article EN cc-by Translational Psychiatry 2017-01-17

Both major depressive disorder (MDD) and posttraumatic stress (PTSD) are characterized by symptoms, abnormalities in brain regions important for cognitive control, response to behavioral therapy (CBT). However, whether a common neural mechanism underlies CBT across diagnoses is unknown.Brain activity during control task was measured using functional magnetic resonance imaging 104 participants: 28 patients with MDD, 53 PTSD, 23 healthy subjects; depression anxiety symptoms were determined on...

10.1016/j.bpsc.2017.12.006 article EN cc-by-nc-nd Biological Psychiatry Cognitive Neuroscience and Neuroimaging 2017-12-28

Doppler ultrasonography of the common carotid artery is used to infer stroke volume change and a wearable ultrasound has been designed improve this workflow. Previously, in human model hemorrhage resuscitation comprising approximately 50,000 cardiac cycles, we found strong, linear correlation between changing volume, measures from signal, however, optimal thresholds for detecting 10% were not reported. In Research Note, present these thresholds, their sensitivities, specificities areas under...

10.1186/s13104-021-05896-y article EN cc-by BMC Research Notes 2022-01-10

Why are some people happier than others? This question has intrigued many researchers. However, limited work addressed this within a neuroscientific framework.The present study investigated the neural correlates of trait happiness using resting-state functional magnetic resonance imaging (rs-fMRI) approach. Specifically, regional homogeneity (ReHo) was examined on two groups young adults: happy and unhappy individuals (N = 25 per group).Decreased ReHo in relative to observed prefrontal...

10.1371/journal.pone.0085181 article EN cc-by PLoS ONE 2014-01-15

Working memory (WM) is central to the acquisition of knowledge and skills throughout childhood adolescence. While numerous behavioral task-based functional magnetic resonance imaging (fMRI) studies have examined WM development, few used resting-state fMRI (R-fMRI). Here, we present a systematic R-fMRI examination age-related differences in neural indices verbal performance cross-sectional pediatric sample (ages: 7–17; n = 68), using data-driven approaches. Verbal capacity was measured with...

10.1016/j.dcn.2015.07.007 article EN cc-by Developmental Cognitive Neuroscience 2015-08-07

What is a good life and how it can be achieved one of the fundamental issues. When considering life, there division between hedonic (pleasure attainment) eudaimonic well-being (meaning pursuing self-realization). However, an integrated approach that compare brain functional structural differences these two forms lacking. Here, we investigated individual tendency to relative well-being, measured using balance (EHB) index, reflected in features key network well-being-the default mode (DMN). We...

10.1093/scan/nsx078 article EN cc-by-nc Social Cognitive and Affective Neuroscience 2017-06-08

Despite widespread use of cognitive behavioral therapy (CBT) in clinical practice, its mechanisms with respect to brain networks remain sparsely described. In this study, we applied tools from graph theory and network science better understand the transdiagnostic neural treatment for depression. A sample 64 subjects was included a study dynamics: 33 patients (15 MDD, 18 PTSD) received longitudinal fMRI resting state scans before after 12 weeks CBT. Depression severity rated on...

10.1038/s41380-018-0201-7 article EN cc-by Molecular Psychiatry 2018-08-13

Multilayer network models have been proposed as an effective means of capturing the dynamic configuration distributed neural circuits and quantitatively describing how communities vary over time. Beyond general insights into brain function, a growing number studies begun to employ these methods for study individual differences. However, test-retest reliabilities multilayer measures yet be fully quantified or optimized, potentially limiting their utility difference studies. Here, we...

10.1016/j.neuroimage.2020.117489 article EN cc-by-nc-nd NeuroImage 2020-10-24

The purposes of this study were to examine the impact 3 weeks amphetamine administration on intrinsic connectome-wide connectivity patterns in adults with attention-deficit/hyperactivity disorder (ADHD) and explore association between stimulant-induced symptom improvement functional alteration.Participants included 19 (age 20-55 years) diagnosed ADHD using Diagnostic Statistical Manual Mental Disorders, 4th ed., Text Revision (DSM-IV-TR) criteria per Adult Clinician Scale taking part trials....

10.1089/cap.2015.0243 article EN Journal of Child and Adolescent Psychopharmacology 2016-03-30

Cognitive impairment is a common complication of type 2 diabetes mellitus (T2DM), and early cognitive dysfunction may be associated with abnormal changes in the cerebral cortex. This retrospective study aimed to investigate cortical thickness-based structural topological network T2DM patients without mild (MCI). Fifty-six 59 healthy controls underwent neuropsychological assessments sagittal 3-dimensional T1-weighted magnetic resonance imaging. Then, we combined graph theoretical analysis...

10.3389/fnins.2024.1327061 article EN cc-by Frontiers in Neuroscience 2024-01-24
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