A5050856611- Education, Healthcare and Sociology Research
- Research in Social Sciences
- Health, psychology, and well-being
- DNA Repair Mechanisms
- Calcium signaling and nucleotide metabolism
- Cellular transport and secretion
- Migration, Health and Trauma
- Health disparities and outcomes
- RNA modifications and cancer
- Health Systems, Economic Evaluations, Quality of Life
- Economic and Environmental Valuation
- Healthcare Policy and Management
- Bacterial Genetics and Biotechnology
- Signaling Pathways in Disease
- Psychiatric care and mental health services
- School Health and Nursing Education
- HIV Research and Treatment
- Biotin and Related Studies
- Fish Ecology and Management Studies
- HIV/AIDS drug development and treatment
- Pregnancy-related medical research
- Advanced Topics in Algebra
- COVID-19 and healthcare impacts
- Neuroscience and Neural Engineering
- Mental Health Treatment and Access
University of Oslo
1998-2024
Norwegian Institute of Public Health
2010-2024
Posten (Norway)
2024
Haraldsplass Diakonale Sykehus
2024
St Olav's University Hospital
2024
Norwegian University of Science and Technology
2024
Oslo University Hospital
2004-2023
Akershus University Hospital
2017
Institutt for Eksperimentell Medisinsk Forskning
2017
Uppsala University
2017
Overexpression of the epidermal growth factor (EGF) receptor (EGFR) in cancer cells correlates with tumor malignancy and poor prognosis for patients. For this reason, EGFR has become one main targets anticancer therapies. Structural data obtained last few years have revealed molecular mechanism ligand-induced dimerization subsequent signal transduction, also how is blocked by either monoclonal antibodies or small molecules. Nimotuzumab (also known as h-R3) a humanized antibody that been...
Earlier studies have shown that people with low level of education increased rates mental health problems. The aim the present study is to investigate association between and psychological distress, explore which extent mediated by sense mastery, social variables like support, negative life events, household income, employment marital status.The data for were obtained from Level Living Survey conducted Statistics Norway in 2002. Data on distress psychosocial gathered a self-administered...
Ethnic discrimination is a relatively common experience among immigrants and ethnic minorities. The of can have detrimental effects on an individual's health well-being. This study investigated the association between perceived general mental in Norway, order to identify potential protective factors. Using data from Living Conditions Survey Immigrants 2016, our sample consisted 4294 participants aged 16–66 years 12 different countries. Participants were asked about variety themes including...
The oxidation resistance gene 1 (OXR1) prevents oxidative stress-induced cell death by an unknown pathway. Here, depletion of human OXR1 (hOXR1) sensitized several lines to hydrogen peroxide-induced stress, reduced mtDNA integrity, and increased apoptosis. In contrast, hOXR1 in cells lacking showed no significant change ROS or viability, suggesting that intracellular increase stress levels avoid a vicious cycle damage formation. Furthermore, expression p21 the antioxidant genes GPX2 HO-1 was...
Access to green space is considered beneficial mental and physical health, though the causal pathways are not completely clear. Accordingly, objective of this study was examine how access associated with low distress general health among older adults.
The aim of the present study was to examine what extent observed gender differences in mental health are associated with protective factors social support, sense coherence and participation regular physical activity more generally, engagement organized or unorganized other people.This based upon a cross-sectional regional survey Norway, conducted during winter 2015-2016, three southern counties; Aust-Agder, Vest-Agder Vestfold. focused on young adults, comparing age groups; 18-24 years old...
Late-life depression is a common condition and challenging public health problem. A lack of social support strongly associated with psychological distress. Senior centres seem to be suitable arenas for community-based promotion interventions, although few studies have addressed this subject. The objectives were examine the effect preventive senior centre group programme consisting weekly meetings, on support, quality life. questionnaire was sent random sample 4,000 persons over 65 in Oslo,...
Background— Chromogranin A (CgA) levels have previously been found to predict mortality in heart failure (HF), but currently no information is available regarding CgA processing HF and whether the fragment catestatin (CST) may directly influence cardiomyocyte function. Methods Results— was characterized postinfarction mice patients with acute HF, functional role of CST explored experimental models. Myocardial biopsies from not sham-operated mice, demonstrated high molecular weight bands....
Oxidation resistance gene 1 (OXR1) protects cells against oxidative stress. We find that male mice with brain-specific isoform A knockout (Oxr1A-/-) develop fatty liver. RNA sequencing of Oxr1A-/- liver indicates decreased growth hormone (GH) signaling, which is known to affect metabolism. Indeed, Gh expression reduced in pituitary gland and rat adenoma cell-line GH3. show fasting-blood GH levels. Pull-down proximity ligation assays reveal OXR1A associated arginine methyl transferase PRMT5....
Norway and Sweden picked two different ways to mitigate the dissemination of SARS-CoV-2 virus. introduced strictest lockdown in Europe with strict border controls intense virus tracking all local outbreaks while did not. That resulted 477 COVID-19 deaths (Norway) 9737 (Sweden) 2020, respectively.
ADVERTISEMENT RETURN TO ISSUEPREVArticleNEXTPurification and Properties of the Alkylation Repair DNA Glycosylase Encoded by MAG Gene from Saccharomyces cerevisiaeMagnar Bjors, Arne Klungland, Rune F. Johansen, Erling SeebergCite this: Biochemistry 1995, 34, 14, 4577–4582Publication Date (Print):April 11, 1995Publication History Published online1 May 2002Published inissue 11 April 1995https://doi.org/10.1021/bi00014a010RIGHTS & PERMISSIONSArticle Views70Altmetric-Citations36LEARN ABOUT THESE...
Aims: The senior centre is the only welfare service in Norwegian elder care serving both fit and less functional pensioners over 65 years. aim of study was to determine socio-demographic, psychosocial health characteristics users centres relation non-users order find out who can benefit from service. Methods: Data collected Population Register for all persons living at home years two municipal districts Oslo. A random sample drawn limited 4,000 total number residents years, 2,000 each...
Bacteriocin production in the lactic acid bacterium Lactobacillus plantarum C11 is regulated through a quorum sensing based pathway involving two highly homologous response regulators (59% identity and 76% similarity), PlnC as transcriptional activator PlnD repressor. Previous vitro studies have shown that both bind, homodimers, to same DNA regulatory repeats exert their functions. As genes for these proteins are located on auto-regulatory operon, hence being co-expressed upon gene...
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The AAG family of 3-methyladenine DNA glycosylases was initially thought to be limited mammalian cells, but genome sequencing efforts have revealed the presence homologous proteins in certain prokaryotic species as well. Here, we report first molecular characterization a functional homologue, i.e. YxlJ, termed bAag, from Bacillus subtilis. B. subtilis aag gene expressed Escherichia coli, and protein purified homogeneity. As expected, Aag found glycosylase, which releases 3-alkylated purines...
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