A5067699129- interferon and immune responses
- Herpesvirus Infections and Treatments
- Immune Response and Inflammation
- Animal Nutrition and Physiology
- Peripheral Neuropathies and Disorders
- Protein Interaction Studies and Fluorescence Analysis
- Lipid metabolism and disorders
- Congenital heart defects research
- Education Systems and Policy
- Pregnancy and preeclampsia studies
- Wastewater Treatment and Nitrogen Removal
- Circular RNAs in diseases
- Reproductive tract infections research
- NF-κB Signaling Pathways
- TGF-β signaling in diseases
- Reproductive Physiology in Livestock
- Traditional Chinese Medicine Analysis
- Traditional Chinese Medicine Studies
- Cancer-related molecular mechanisms research
- Drug Transport and Resistance Mechanisms
- RNA Interference and Gene Delivery
- Systemic Lupus Erythematosus Research
- Higher Education and Teaching Methods
- Neurological Disease Mechanisms and Treatments
- Meat and Animal Product Quality
Yangzhou University
1998-2023
To determine whether age at menarche (AAM), first live birth (AFB), and estradiol levels are causally correlated with the development of systemic lupus erythematosus (SLE).A two-sample Mendelian randomization (MR) analysis was performed after data collected from a dataset genome-wide association studies (GWASs) related to SLE (as outcome), open access databases find statistics AAM, AFB, exposure).In our study, negative causal correlation between AAM confirmed by MR (MR egger: beta = 0.116,...
1. Highly palatable and nutritious meat products can be produced through dietary interventions. Previous studies have shown that forage feeding has a significant impact on the growth performance nutrition of cattle in various regions, but whether same effects induced geese remains unclear. 2. Three hundred sixty Yangzhou goslings were divided according to body weight at 29 d old, assigned one 4 treatments raised separate pens. The applied (A) grazing, (B) grain supplemental diet (64 70 d),...
To investigate the clinical characteristics, imaging changes and early diagnostic methods of neuropsychiatric systemic lupus erythematosus (NPSLE).Thirty-five SLE patients, which 16 had overt symptoms, underwent examination for multiple autoantibodies, including anti-double-stranded DNA (anti-dsDNA) antibody, anti-nucleosome anti-cardiac-phospholipid antibody (aCL)-IgG, aCL-IgM, anti-β2-glycoprotein I anti-ribosomal P SLEDAI score every patient was recorded. All patients further received...
1. The aim of this study was to identify the active control area duck retinoic acid-inducible gene I (duRIG-I) core promoter, predict binding sites transcription factors and provide a theoretical basis for duRIG-I function mechanism regulation. 2. promoter region obtained from Ensembl; CpG island in predicted online; methylation status detected by bisulphite sequencing PCR method. 3. There an obvious with total 44 CG dinucleotides. However, level hypomethylation (0.2%). 4. transcriptional...
1. Albumin (ALB) is a serum protein most highly expressed in liver and regarded as an effective indicator for pathologies. The objectives of this study were to determine the expression duck ALB gene (duALB) various non-hepatic tissues identify potential cis-regulatory elements promoter. 2. A model was established assess duALB promoter activity different cell lines by construction promoter-driven GFP (Green Fluorescent Protein)-expressing vector, which exhibited high liver-derived cells lower...
Mothers against decapentaplegic homolog 4 (SMAD4) is an important protein in animal reproduction. It plays pivotal roles cellular pathways, including apoptosis. The expression profile of the SMAD4 gene goose ovarian follicles has not been reported. In this study, coding sequence was cloned from Yangzhou goose. A phylogenetic analysis performed and mRNA examined various tissues using quantitative real-time PCR. An alternative splice form SMAD4, SMAD4-b having 1656 bp, identified. SMAD4-a...
1. Myxovirus resistance (Mx) is a protein produced by the interferon-induced natural immune response with broad spectrum antiviral function. However, role and expression characteristics of Mx gene in defence against viral infection goose have not yet been reported.2. This study found 2576 bp genomic sequence 2112 mRNA for Mx, encoding 703 amino acids. Multiple alignments acid sequences showed that Yangzhou (goMx) had 86.99% similarity to mallard duck (Anas platyrhynchos).3. Tissue-specific...