A5085091229- Animal Nutrition and Physiology
- Cancer-related molecular mechanisms research
- Genetic and phenotypic traits in livestock
- Livestock and Poultry Management
- MicroRNA in disease regulation
- interferon and immune responses
- Biochemical Analysis and Sensing Techniques
- Meat and Animal Product Quality
- Animal Virus Infections Studies
- Genetic Mapping and Diversity in Plants and Animals
- Animal Genetics and Reproduction
- melanin and skin pigmentation
- Genetic diversity and population structure
- Peroxisome Proliferator-Activated Receptors
- Circular RNAs in diseases
- Gut microbiota and health
- Identification and Quantification in Food
- Chromosomal and Genetic Variations
- Immune Response and Inflammation
- Genetic and Clinical Aspects of Sex Determination and Chromosomal Abnormalities
- Adipose Tissue and Metabolism
- Aquaculture disease management and microbiota
- RNA and protein synthesis mechanisms
- Herpesvirus Infections and Treatments
- RNA Interference and Gene Delivery
Yangzhou University
2016-2025
Shenyang Institute of Computing Technology (China)
2024
Chinese Academy of Sciences
2024
Ministry of Agriculture and Rural Affairs
2023
State Forestry and Grassland Administration
2022
Poultry Research Institute
2009-2016
Chinese Academy of Agricultural Sciences
2016
Chinese Academy of Surveying and Mapping
2013
Microchromosomes are prevalent in nonmammalian vertebrates [P. D. Waters et al. , Proc. Natl. Acad. Sci. U.S.A. 118 (2021)], but a few of them missing bird genome assemblies. Here, we present new chicken reference containing all autosomes, Z and W chromosome, with gaps closed except for the W. We identified ten small microchromosomes (termed dot chromosomes) distinct sequence epigenetic features, among which six were newly assembled. Those chromosomes exhibit extremely high GC content level...
Comparative population genomics and genome-wide association studies (GWAS) offer opportunities to discover human-driven detectable signatures within the genome. From point of view evolutionary biology, identification genes associated with domestication traits is interest for elucidation selection these traits. To this end, an F2 ducks, consisting 275 was genotyped using a whole genome re-sequence containing 12.6 Mb single nucleotide polymorphisms (SNPs) four plumage colors. GWAS used...
Rodent infestation is a global biological problem. Rodents are widely distributed worldwide, cause harm to agriculture, forestry, and animal husbandry production spread variety of natural focal diseases. In this study, 10 ecological niche models were combined into an ensemble model assess the distribution suitable habitats for Rhombomys opimus predict impact future climate change on R. under low, medium high socioeconomic pathway scenarios CMIP6.In general, with exception extreme climates...
Altitudinal adaptation is a key factor in species formation and leads to increased diversity. Chickens are one of the most widely distributed important domesticated species, making them ideal models for studying evolution altitudinal adaptation. Therefore, we downloaded analyzed total genome data 160 individual chickens from seven sampling regions at two different altitudes (>3000 m <600 m). In total, 21,672,487 high-quality single-nucleotide polymorphisms were selected used subsequent...
ABSTRACT Avian leukosis virus subgroup J (ALV-J) poses a significant threat to the poultry industry; yet, our understanding of its replication and pathogenic mechanisms is limited. The Ten-Eleven Translocation 2 (TET2) an indispensable regulatory factor in active DNA demethylation immune response regulation. This study reports time-dependent decrease TET2 levels following ALV-J infection shows that reduction protein mediated by autophagy pathway. Mechanistically, we found accumulation Env at...
Excessive deposition of abdominal fat will cause a waste resources. In order to explore the key miRNAs and circRNA/lncRNA-miRNA-mRNA ceRNA regulatory network involved in regulating deposition, hematoxylin eosin (H&E) staining was performed on tissues ducks high rate group (HF) low (LF) at 21 42 days age, whole transcriptome sequencing HF LF groups age. The results showed that number adipocytes significantly higher than age (p < 0.001), while lower 0.001). addition, screened out total...
B-cell lymphoma/leukemia 11B (Bcl11b) plays roles in cell proliferation and apoptosis holds a pivotal position within the immune system. Our previous studies have demonstrated that Bcl11b can promote to curb ALV-J infection. To gain insights into molecular mechanisms underlying expression regulation chickens, we constructed various truncated dual luciferase reporter vectors analyzed promoter region of Bcl11b. We employed promoter-binding TF profiling assay site-directed mutagenesis level...
Abstract MicroRNA (miRNA)‐1 and miRNA‐133 are derived from the same bicistronic pairs with roles in skeletal muscle development. Many investigations have focused on role of miRNA‐1 regulation development mammals fish. However, mechanisms underlying differences between different breeds not well known. Our study found that weights body breast at 42 days age were greater Cherry Valley ducks than Putian areas fibers increased age; always those ducks. Besides, quantitative reverse‐transcriptase...
The present study was conducted to evaluate the effects of different rearing methods and stocking densities on carcass yield proximate composition meat in small-sized ducks. A total 555 one-day-old birds were randomly allocated six treatment groups (three replicates per treatment, sex ratio 1/1) with a 2 × 3 factorial arrangement two (reared cage or net) three (5 [low], 7 [medium], 9 [high] birds/m2) until day 70. Five male five female from each replicate selected processed determine yield....
Given an increasing trend in slaughter and chilling for the sale of chickens China, it is important to determine marketable age chilled sales. This study determined effects two ages on body measurements, carcass traits, meat quality yellow-feathered chickens. A total 360 healthy one-day-old male Xueshan were raised six pens (straw-covered floor, numbered 1 6) treated same manner (free access food water) until day 100. Sixty from 3 4 6 selected at (90 100 days), respectively. One...
The objective of this study was to determine the regulatory effects gut microbiota on feed efficiency (FE) small-sized meat ducks by evaluating correlations between and residual intake (RFI). A total 500 21-day-old healthy male with similar initial body weights (645 ± 15.0 g) were raised contemporaneously in same experimental facility until slaughter at 56 days age. In total, nine low-RFI (LR) high-RFI (HR) birds selected for further composition functional analyses based production...
South Asia and Southeast are the origins of domestic chickens rich in poultry genetic resources, resulting many unique local chicken breeds. However, with rapid intensification farming worldwide, breeds threatened extinction. In response to China's "One Belt, One Road" policy, it is imperative strengthen conservation breeding China Vietnam. This study characterized 18 microsatellite molecular markers analyze diversity 21 populations southern (Yunnan Guangxi Provinces) Vietnam, breed...
This study investigated the effects of floor and cage rearing systems on performance, meat quality, enteric microorganisms male female yellow feather broilers. Two hundred Xueshan chickens (42 days old; 100 each sex) were divided into four groups, according to sex system (stainless-steel or litter floor). Male cage-reared broilers exhibited better (P<0.001) performance higher (P≤0.001) eviscerated percentage than floor-reared The interaction between had an effect (P<0.05) breast thigh...
Background Gut microbial composition is dependent on diet. Geese are herbivores and can digest crude fibre, but the relationship between of microbiota a fibre-rich diet in geese not well understood. Results Here, caecal faecal samples were collected simultaneously from all-grass-fed high-grain-fed hypervariable V3–V4 regions bacterial 16S rRNA gene sequenced. The results was identified that high-grass-fed possessed significantly higher alpha diversity both caecum faeces compared with...
Feed efficiency (FE) is a major economic trait of meat duck. This study aimed to evaluate the effects residual feed intake (RFI) divergence on growth performance, carcass traits, quality, and blood biochemical parameters in small-sized ducks. A total 500 healthy 21-day-old male ducks were housed individual cages until slaughter at 63 d age. The performance was determined for all yield, selected 30 high-RFI (HRFI) low-RFI (LRFI) In terms RFI, conversion ratio (FCR), average daily (ADFI) found...
The study investigated the effects of feed efficiency (residual intake, RFI and residual intake gain, RIG) on production performance small-sized meat ducks. Ninety ducks with intermediate extreme (high low) values were selected from 1,083 male similar body weight, 3 groups then redivided according to RIG. For both measures, conversion ratio (FCR) average daily (ADFI) efficient significantly lower than those inefficient (P < 0.05), while weight gain (RG) was higher in 0.05). Inefficient-RFI...
This study was performed to evaluate the effects of different rearing methods on growth performance, carcass yield, and meat quality small-sized ducks. A total 420 healthy 21-day-old birds randomly allocated 2 treatment groups (6 replicates per treatment, sex ratio 1/1) subjected (furnished cage plastic wire-floor) until d 63. Growth performance measured in all birds. Three males 3 females from each replicate were selected evaluated determine yield quality. In terms method affected final...
With continuously increasing living standards and health requirements of consumers, meat quality is becoming an important consideration while buying products. To date, no genome-wide association study (GWAS) for copy number variants (CNVs) single nucleotide polymorphisms (SNPs) has been conducted to reveal the genetic effects on in ducks. This analyzed phenotypic correlation heritability fat, water, collagen, protein content duck breast muscle. identify candidate quality, we performed a GWAS...
The liver is the main site of fat synthesis and plays an important role in study deposition poultry. In this study, we investigated developmental changes duckling livers isolated primary duck hepatocytes. Firstly, observed morphological from embryonic period to first week after hatching. Liver weight increased with age. Hematoxylin-eosin Oil Red O staining analyses showed that hepatic lipids gradually during declined post-hatching. samples were collected 21-day-old embryos for hepatocyte...
Considering that dietary fatty acid composition affects the polyunsaturated acids (PUFAs) profile of duck meat, current study sought to evaluate effects feeding time a linseed oil diet on performance, meat quality, plasma biochemical indicators, profile, and gene expression. Linseed is rich source n-3 PUFAs. To this end, we selected 168 28-day-old Chinese crested ducks divided them into three groups. The control group was fed basic diet, fat in experimental replaced by 2% oil. Ducks two...
Abstract The Chinese crested (CC) duck is a unique indigenous waterfowl breed, which has crest cushion that affects its survival rate. Therefore, the CC an ideal model to investigate genetic compensation response maintain stability. In present study, we first generated chromosome-level genome of ducks. Comparative genomics revealed genes related tissue repair, immune function, and tumors were under strong positive selection, indicating these adaptive changes might enhance cancer resistance...
Spermatogenesis is a complex process that involves many elements. However, until now, little known at the molecular level about spermatogenesis in poultry. Here we investigated microRNAs and their target genes may be involved germ cell development spermatogonial chicken. We used next-generation sequencing to analyze miRNA expression profiles three types of germline cells: primordial cells (PGCs), stem (SSCs), spermatogonia (Sp) during early stage spermatogenesis. After validated candidate...
AbstractAround the world, there are 20 types of wild and about 70 domestic quail breeds or strains, including laboratory commercial quail. Although all quails were derived from many obvious differences evident today. However, how these occurred which population was first to be domesticated, remains unclear. This paper systematically presents history development in China 770 B.C. end century. Taking into account recent research on some structural loci quail, light survey reports present...
1. Highly palatable and nutritious meat products can be produced through dietary interventions. Previous studies have shown that forage feeding has a significant impact on the growth performance nutrition of cattle in various regions, but whether same effects induced geese remains unclear. 2. Three hundred sixty Yangzhou goslings were divided according to body weight at 29 d old, assigned one 4 treatments raised separate pens. The applied (A) grazing, (B) grain supplemental diet (64 70 d),...