Guohong Chen

ORCID: 0000-0003-1967-0728
Publications
Citations
Views
---
Saved
---
About
Contact & Profiles
Research Areas
  • Animal Nutrition and Physiology
  • Animal Genetics and Reproduction
  • Peroxisome Proliferator-Activated Receptors
  • RNA and protein synthesis mechanisms
  • Meat and Animal Product Quality
  • Genetic diversity and population structure
  • Genetic and phenotypic traits in livestock
  • interferon and immune responses
  • Livestock and Poultry Management
  • Immune Response and Inflammation
  • CRISPR and Genetic Engineering
  • Genetic and Clinical Aspects of Sex Determination and Chromosomal Abnormalities
  • MicroRNA in disease regulation
  • Identification and Quantification in Food
  • Genomics and Phylogenetic Studies
  • Cancer-related molecular mechanisms research
  • Molecular Biology Techniques and Applications
  • bioluminescence and chemiluminescence research
  • Biochemical Analysis and Sensing Techniques
  • Antimicrobial Peptides and Activities
  • Metabolomics and Mass Spectrometry Studies
  • Sperm and Testicular Function
  • Chromosomal and Genetic Variations
  • Regulation of Appetite and Obesity
  • Machine Learning in Bioinformatics

Yangzhou University
2015-2025

Ministry of Agriculture and Rural Affairs
2023

Zhengzhou Children's Hospital
2021

Zhengzhou University
2021

Fudan University
2010-2017

RIKEN
2012-2017

Guang’anmen Hospital
2009-2016

Chinese Academy of Medical Sciences & Peking Union Medical College
2015-2016

State Key Laboratory of Surface Physics
2013

Poultry Research Institute
2009-2011

Abstract MicroRNA (miRNA)‐1 and miRNA‐133 are derived from the same bicistronic pairs with roles in skeletal muscle development. Many investigations have focused on role of miRNA‐1 regulation development mammals fish. However, mechanisms underlying differences between different breeds not well known. Our study found that weights body breast at 42 days age were greater Cherry Valley ducks than Putian areas fibers increased age; always those ducks. Besides, quantitative reverse‐transcriptase...

10.1002/jcp.26857 article EN Journal of Cellular Physiology 2018-11-23

The present study was conducted to evaluate the effects of different rearing methods and stocking densities on carcass yield proximate composition meat in small-sized ducks. A total 555 one-day-old birds were randomly allocated six treatment groups (three replicates per treatment, sex ratio 1/1) with a 2 × 3 factorial arrangement two (reared cage or net) three (5 [low], 7 [medium], 9 [high] birds/m2) until day 70. Five male five female from each replicate selected processed determine yield....

10.1016/j.psj.2019.09.006 article EN cc-by-nc-nd Poultry Science 2020-02-28

Excessive deposition of abdominal fat will cause a waste resources. In order to explore the key miRNAs and circRNA/lncRNA-miRNA-mRNA ceRNA regulatory network involved in regulating deposition, hematoxylin eosin (H&E) staining was performed on tissues ducks high rate group (HF) low (LF) at 21 42 days age, whole transcriptome sequencing HF LF groups age. The results showed that number adipocytes significantly higher than age (p < 0.001), while lower 0.001). addition, screened out total...

10.3390/ani15040506 article EN cc-by Animals 2025-02-11

Abstract Background Duck is an ancient domesticated animal with high economic value, used for its meat, eggs, and feathers. However, the origin of indigenous Chinese ducks remains elusive. To address this question, we performed whole-genome resequencing to first explore genetic relationship among variants these domestic their potential wild ancestors in eastern China, as well understand how genomes were shaped by different natural artificial selective pressures. Results Here, report 60 from...

10.1186/s12864-021-07710-2 article EN cc-by BMC Genomics 2021-05-31

Feed efficiency (FE) is a major economic trait of meat duck. This study aimed to evaluate the effects residual feed intake (RFI) divergence on growth performance, carcass traits, quality, and blood biochemical parameters in small-sized ducks. A total 500 healthy 21-day-old male ducks were housed individual cages until slaughter at 63 d age. The performance was determined for all yield, selected 30 high-RFI (HRFI) low-RFI (LRFI) In terms RFI, conversion ratio (FCR), average daily (ADFI) found...

10.1016/j.psj.2022.101990 article EN cc-by-nc-nd Poultry Science 2022-06-02

In this study, we sought to determine the effects of intestinal flora on feed efficiency meat ducks by evaluating correlation between and residual intake. The F

10.1016/j.psj.2024.103836 article EN cc-by-nc-nd Poultry Science 2024-05-07

The allogeneic transplantation of primordial germ cells (PGCs) derived from somatic overcomes the limitation avian cloning. Here, we transdifferentiate chicken embryo fibroblasts (CEFs) black feathered Langshan chickens to PGCs and transplant them into White Plymouth Rock embryos produce viable offspring with characteristics inherited donor. We express Oct4/Sox2/Nanog/Lin28A (OSNL) reprogram CEFs induced pluripotent stem (iPSCs), which are further differentiate by BMP4/BMP8b/EGF. DNA...

10.1038/s41467-021-23242-5 article EN cc-by Nature Communications 2021-05-20

This study was performed to evaluate the effects of different rearing methods on growth performance, carcass yield, and meat quality small-sized ducks. A total 420 healthy 21-day-old birds randomly allocated 2 treatment groups (6 replicates per treatment, sex ratio 1/1) subjected (furnished cage plastic wire-floor) until d 63. Growth performance measured in all birds. Three males 3 females from each replicate were selected evaluated determine yield quality. In terms method affected final...

10.1016/j.psj.2021.101520 article EN cc-by-nc-nd Poultry Science 2021-10-11

Considering that dietary fatty acid composition affects the polyunsaturated acids (PUFAs) profile of duck meat, current study sought to evaluate effects feeding time a linseed oil diet on performance, meat quality, plasma biochemical indicators, profile, and gene expression. Linseed is rich source n-3 PUFAs. To this end, we selected 168 28-day-old Chinese crested ducks divided them into three groups. The control group was fed basic diet, fat in experimental replaced by 2% oil. Ducks two...

10.1016/j.psj.2023.102896 article EN cc-by-nc-nd Poultry Science 2023-06-30

1. The objective of this study was to investigate the effects dietary probiotic supplementation on liver X receptor alpha (LXRα) and cholesterol 7α-hydroxylase (CYP7α1) mRNA levels, protein enzymatic activities fat metabolism in Cherry Valley Pekin ducks. 2. A total 750 one-day-old ducks were randomly divided into 5 groups with three replicates 50 each a completely randomised experiment. Each group fed basal diet supplemented 0, 500, 1000, 1500 or 2000 mg probiotics/kg. 3. Body rate feed...

10.1080/00071668.2014.1000821 article EN British Poultry Science 2015-01-06

Abstract The Chinese crested (CC) duck is a unique indigenous waterfowl breed, which has crest cushion that affects its survival rate. Therefore, the CC an ideal model to investigate genetic compensation response maintain stability. In present study, we first generated chromosome-level genome of ducks. Comparative genomics revealed genes related tissue repair, immune function, and tumors were under strong positive selection, indicating these adaptive changes might enhance cancer resistance...

10.1016/j.gpb.2023.08.002 article EN cc-by-nc-nd Genomics Proteomics & Bioinformatics 2023-06-01

1. Highly palatable and nutritious meat products can be produced through dietary interventions. Previous studies have shown that forage feeding has a significant impact on the growth performance nutrition of cattle in various regions, but whether same effects induced geese remains unclear. 2. Three hundred sixty Yangzhou goslings were divided according to body weight at 29 d old, assigned one 4 treatments raised separate pens. The applied (A) grazing, (B) grain supplemental diet (64 70 d),...

10.1080/00071668.2017.1307942 article EN British Poultry Science 2017-03-29

This study was conducted to investigate the effects of different free-range systems on growth performance, carcass traits, and meat quality geese. Grass pasture zones in area were selected, 28 d-old male Yangzhou geese with similar body weights (1.57 ± 0.12 kg) randomly allocated one three conditions: (A) conditions apron during 9:00 a.m.–4:00 p.m. (10–20 m from shed grass pasture); (B) outer range a.m. 4:00 (beyond 50 (C) barn system. Free range-reared had higher weight gain after 42 days...

10.1080/10495398.2022.2147842 article EN Animal Biotechnology 2022-11-21

Plumage color is an intuitive external poultry characteristic with rich manifestations and complex genetic mechanisms. In our previous study, we observed that there were more dark variations in plumage the F

10.1016/j.psj.2024.104107 article EN cc-by-nc-nd Poultry Science 2024-07-17

1. The low reproductive performance of geese has seriously hampered the development industry. Reproductive performance, particularly egg laying rate mainly depends on follicle. Previous studies have shown that follicle-stimulating hormone (FSH) plays an important role in process follicular development, but exact underlying mechanism remains unclear. 2. This study showed FSH stimulated granulosa cell proliferation a dose-dependent manner. effect treatment was greatest at dose 100 mIU/ml for...

10.1080/00071668.2018.1459474 article EN British Poultry Science 2018-05-03

AbstractTwenty four Chinese native duck breeds were studied to estimate genetic diversity and structure using microsatellite markers. The relationships between analyzed in combination with their geographic distribution. A total of 28 markers amplified. All the exhibited diversity, through estimation polymorphic information content (PIC) mean heterozygosity (H) index. populations was 0.569, while PIC values for relatively high. Neighbour-joining used calculate distances. Cluster analysis...

10.1017/s0043933906001152 article EN World s Poultry Science Journal 2006-12-01

Based on density-functional calculation and genetic algorithm structure search, we propose a series of 16-coordinate core–shell clusters: M@Li16(M = Ca, Sr, Ba, Ti, Zr, Hf). A tetrahedral (Td) with an outer shell 16 lithium atoms one enclosed heavy atom is found to be the global minimum in structural exploration BaLi16 based algorithm. This also has lower energy compared other isomers employed all MLi16 clusters. In this structure, are bonded together by metallic bonds alkali (IA)...

10.1039/c2nr00056c article EN Nanoscale 2012-01-01

Piwi-interacting RNAs (piRNAs) play a key role in spermatogenesis. Here, we describe the piRNAs profiling of primordial germ cells (PGCs), spermatogonial stem (SSCs), and spermatogonium (Sp) during early-stage spermatogenesis chicken. We obtained 31,361,989 reads from PGCs, 31,757,666 SSCs, 46,448,327 Sp cells. The length distribution three samples showed peaks at 33 nt. resulting genes were subsequently annotated against Gene Ontology (GO) database. Five (RPL7A, HSPA8, Pum1, CPXM2, PRKCA)...

10.1371/journal.pone.0151780 article EN cc-by PLoS ONE 2016-04-05

1. Endothelin receptor B subtype 2 (EDNRB2) is a paralog of EDNRB, which encodes 7-transmembrane G-protein coupled receptor. Previous studies reported that EDNRB was essential for melanoblast migration in mammals and ducks.2. Muscovy ducks have different plumage colour phenotypes. Variations EDNRB2 coding sequences (CDSs) mRNA expression levels were investigated 4 duck phenotypes, including black, black mutant, silver white head.3. The gene from cloned; it had length 6435 bp encoded 437...

10.1080/00071668.2016.1259531 article EN British Poultry Science 2016-11-23

Goose (Anser cygnoides) are highly broody with low egg production, and large number of granulosa cells undergo apoptosis during broodiness. Our previous study has found that miR-34c-5p was abundant in the ovary goose broodiness phenotype. However, mechanism regulates function remains unclear. Here, we demonstrated had higher levels than laying by qRT-PCR. The dual luciferase reporter assay showed Bcl2 identified as a direct target miR-34c-5p, which could be negatively regulated miR-34c-5p....

10.1080/10495398.2021.1886943 article EN Animal Biotechnology 2021-02-25
Coming Soon ...