A5058878423- Bacterial biofilms and quorum sensing
- Antimicrobial Peptides and Activities
- Antimicrobial Resistance in Staphylococcus
- Click Chemistry and Applications
- Biochemical and Structural Characterization
- COVID-19 Clinical Research Studies
- Microbial Metabolism and Applications
- Sexual Differentiation and Disorders
- Sperm and Testicular Function
- Ovarian function and disorders
- Infectious Diseases and Mycology
- Phenothiazines and Benzothiazines Synthesis and Activities
- SARS-CoV-2 detection and testing
- Natural Compound Pharmacology Studies
- Bacterial Identification and Susceptibility Testing
- Carbohydrate Chemistry and Synthesis
- SARS-CoV-2 and COVID-19 Research
Universidade Federal Fluminense
2016-2024
Hospitalizations related to Methicillin-resistant Staphylococcus aureus (MRSA) are frequent, increasing mortality and health costs. In this way, study aimed compare the genotypic phenotypic characteristics of MRSA isolates that colonize infect patients seen at two hospitals in city Niterói-Rio de Janeiro, Brazil. A total 147 samples collected between March 2013 December 2015 were phenotyped genotyped identify protein (SPA) gene, mec staphylococcal chromosomal cassette (SCCmec), mecA,...
Obesity has become a major problem in most developed countries. Infertility ranks high among the issues brought by excessive weight gain, particularly as it may affect male sexual function. This study investigated population of Brazilian infertile men an attempt to establish relationship between obesity and infertility.A total 153 had their anthropometric data collected were divided into groups according body mass index waist circumference measurements. Sperm parameters including sperm...
CC398 is a livestock-associated Staphylococcus aureus. However, it has also been isolated from humans with no previous contact livestock. A surveillance of methicillin-resistant S. aureus colonisation among children attending public day care centres and hospitals in Niterói Rio de Janeiro, Brazil, between 2011 2013, resulted the isolation six cases individuals exposure to These isolates showed high frequency erm(C) gene (4/6, 66.7%) induced resistance clindamycin, relatively SEs lukS/lukF...
Following the appearance of several antimicrobial agents to control spread infections, two major challenges have emerged: (i) occurrence and blowout multiresistant bacteria increase chronic diseases (ii) difficult-to-eradicate infections. In this study, we tested five benzoylthiourea derivatives for their ability inhibit stop bacterial growth evaluated possible influence 1,2,4-triazolyl-benzoylthiourea derivative 4 on formation eradication Staphylococcus aureus biofilms. Benzoylthiourea 4,...
Background: Resistance to antimicrobial agents is a major public health problem, being Staphylococcus aureus prevalent in infections hospital and community environments and, admittedly, related biofilm formation biotic abiotic surfaces. Biofilms form complex structured of microorganisms surrounded by an extracellular matrix adhering each other surface that gives them even more protection from resistance against the action agents, as well host defenses. Methods: Aiming control solve these...
We developed three new analogs of the antimicrobial peptide (AMP) Citropin 1.1: DAN-1-13, AJP-1-1, and HHX-2-28, tested their potential antibiofilm activities against Staphylococcus aureus S. pseudintermedius. Potential cytotoxic or hemolytic effects were determined using cultured human keratinocytes erythrocytes to determine safety.
BACKGROUND At the end of December 2019, world faced severe acute respiratory syndrome-coronavirus 2 (SARS-CoV-2), which led to outbreak coronavirus disease 2019 (COVID-19), associated with issues. This virus has shown significant challenges, especially for senior citizens, patients other underlying illnesses, or those a sedentary lifestyle. Serological tests conducted early on have helped identify how is transmitted and curb its spread. The study hypothesis was that rapid serological test...
Staphylococcus aureus is considered the most common opportunistic pathogen in humans, capable of forming biofilm, increasing chances antibiotic resistance and causes several chronic diseases. Biodiversity a source inspiration search for new agents against these microorganisms. Hitherto, efficacy Hypericum sp. extracts as an antibacterial agent has already been demonstrated Gram-positive Gram-negative bacteria. In this study, we observed that until 4 µg/mL, brasiliense extract showed...