A5012858367- Exercise and Physiological Responses
- Muscle Physiology and Disorders
- Cardiovascular and exercise physiology
- Sports Performance and Training
- Muscle metabolism and nutrition
- Growth Hormone and Insulin-like Growth Factors
- Adipose Tissue and Metabolism
- Cancer, Hypoxia, and Metabolism
- Cancer survivorship and care
- Nutrition and Health in Aging
- Heart Rate Variability and Autonomic Control
- Sports injuries and prevention
- Childhood Cancer Survivors' Quality of Life
- Metabolism, Diabetes, and Cancer
- Ovarian function and disorders
- Health and Wellbeing Research
- Neurogenetic and Muscular Disorders Research
- Adipokines, Inflammation, and Metabolic Diseases
- Reproductive Biology and Fertility
- Genetics and Physical Performance
- Chronic Obstructive Pulmonary Disease (COPD) Research
- Cardiovascular Function and Risk Factors
- Diet and metabolism studies
- Biochemical effects in animals
- Hormonal Regulation and Hypertension
National and Kapodistrian University of Athens
2016-2025
University of Thessaly
2022-2024
Eginition Hospital
2023
Evangelismos Hospital
2023
Czech Academy of Sciences, Institute of Physiology
2022
University of Glasgow
2021
University General Hospital Attikon
2021
Frontier Science Foundation-Hellas
2021
University of Pennsylvania
2012-2015
State University of Physical Education and Sport
2004
Insulin-like growth factors (IGFs) are critical for development and of skeletal muscles, but because several tissues produce IGFs, it is not clear which source necessary or sufficient muscle growth. Because production both IGF-I IGF-II, we ablated glucose-regulated protein 94 (GRP94) in murine striated to test the necessity local IGFs normal These mice exhibited smaller muscles with diminished IGF contents contractile function no apparent endoplasmic reticulum stress response. This result...
Abstract: The central nervous system (CNS) is one of the most metabolically active organs and characterized by elevated oxygen requirements, while it possesses a diminished anti-oxidative action. This can result in impairment susceptible glia neurons, due to production reactive species (ROS), ultimately neurodegeneration. Indeed, oxidative stress key component pathophysiological mechanisms plethora diseases, including neurodegenerative disorders. Iron, additionally involved transportation...
Non-communicable diseases (NCDs), including coronary heart disease, stroke, hypertension, type 2 diabetes, dementia, depression and cancers, are on the rise worldwide often associated with a lack of physical activity (PA). Globally, levels PA among individuals below WHO recommendations. A can increase morbidity mortality, worsen quality life economic burden society. In response to this trend, numerous organisations came together under one umbrella in Hamburg, Germany, April 2021 signed...
Insulinlike growth factor-1 (IGF-1) expression is implicated in myocardial pathophysiology, and two IGF-1 mRNA splice variants have been detected rodents, IGF-1Ea mechano-growth factor (MGF). We investigated the pattern of gene transcripts rat myocardium from 1 h up to 8 wks after infarction induced by left anterior descending coronary artery ligation. In addition, we characterized MGF E peptide action their respective signaling H9C2 myocardial-like cells vitro. were significantly increased,...
Muscle adaptation which occurs following eccentric exercise-induced muscle damage has been associated with an acute inflammatory response. The purpose of this study was to investigate serum interleukin-6 (IL-6), osteoprotegerin and receptor activator nuclear factor kB ligand (OPG/RANKL) concentrations damage. We measured changes for several days damage.Ten healthy young males performed exercise protocol using their quadriceps. Blood samples were withdrawn before at 6 h, 2 days, 5 16...
IGF-I is a key regulator of muscle development and growth. The pre-pro-peptide produced by the Igf1gene undergoes several posttranslational processing steps to result in secreted mature protein, which thought be obligate ligand for receptor (IGF-IR). goals this study were determine what forms exist skeletal muscle, whether protein was only form able activate IGF-IR. We measured proportion species murine found that predominant nonglycosylated pro-IGF-I glycosylated pro-IGF-I, retained...