A5100668969- Respiratory viral infections research
- Pneumonia and Respiratory Infections
- Sepsis Diagnosis and Treatment
- COVID-19 Clinical Research Studies
- Nosocomial Infections in ICU
- COVID-19 diagnosis using AI
- Antibiotic Resistance in Bacteria
- Long-Term Effects of COVID-19
- Congenital Diaphragmatic Hernia Studies
- Medical Imaging and Pathology Studies
- Respiratory Support and Mechanisms
- Antimicrobial Resistance in Staphylococcus
- Chronic Obstructive Pulmonary Disease (COPD) Research
- Gut microbiota and health
- Tracheal and airway disorders
- Bacterial Identification and Susceptibility Testing
- Air Quality and Health Impacts
- Neonatal Respiratory Health Research
- MicroRNA in disease regulation
- SARS-CoV-2 and COVID-19 Research
- Inflammation biomarkers and pathways
- COVID-19 impact on air quality
- Machine Learning in Healthcare
- Medical Research and Treatments
- SARS-CoV-2 detection and testing
Chinese PLA General Hospital
2015-2024
Southern Medical University
2024
Guangdong Provincial People's Hospital
2024
Ganzhou People's Hospital
2024
Guangdong Academy of Medical Sciences
2024
University of Arkansas for Medical Sciences
2023
Peking University
2023
State Council of the People's Republic of China
2022
Bethune International Peace Hospital
2014
Chinese People's Liberation Army
2014
This case series uses patient hospital data to summarize the clinical presentation and laboratory imaging findings of 13 patients with confirmed 2019-nCoV infection admitted hospitals in Beijing January 2020.
Fast and accurate identification of microbial pathogens is critical for the proper treatment infections. Traditional culture-based diagnosis in clinics increasingly supplemented by metagenomic next-generation-sequencing (mNGS). Here, RNA/cDNA-targeted sequencing (meta-transcriptomics using NGS (mtNGS)) established to reduce host nucleotide percentage clinic samples combining with Oxford Nanopore Technology (ONT) platforms third-generation sequencing, mtTGS) improve time. It shows that mtNGS...
Abstract Objective The intent of this study was to examine the recovery individuals who had been hospitalized for severe acute respiratory syndrome (SARS) in year following their discharge from hospital. Parameters studied included serum levels SARS coronavirus (SARS-CoV) IgG antibody, tests lung function, and imaging data evaluate changes fibrosis. In addition, we explored incidence femoral head necrosis some recovering SARS. Methods subjects were 383 clinically diagnosed patients Beijing,...
Lung injury due to zinc chloride smoke inhalation is very common in military personnel and leads a high incidence of pulmonary complications mortality. The aim this study was uncover the underlying mechanisms lung using rat model.Histopathology analysis lungs after performed by haematoxylin eosin (H&E) Mallory staining. A model (smoke for 1, 2, 7 14 days) developed. First, isobaric tags relative absolute quantization (iTRAQ) weighted gene co-expression network (WGCNA) were used identify...
Critical illness in the intensive care unit (ICU) has been a global health priority. Systemic nutritional status turned out to be related prognosis of critically ill patients. The albumin-globulin ratio (AGR) reported novel prognostic factor many diseases. This study is aimed at investigating whether AGR could predict mortality risk patients.We enrolled 582 adult patients admitted respiratory (RICU). We collected clinical and laboratory data. X-tile software was used determine optimal...
Objective: The goal of this study was to examine the prognostic performance optical flow ratio (OFR) among patients with coronary artery disease (CAD) after percutaneous intervention (PCI). Methods: We recruited CAD undergoing coherence tomography (OCT)-directed PCI between January 2019 and June 2021 for our single-center, hospital-based, retrospective cohort investigation. assessed link post-PCI OFR major adverse cardiovascular events (MACE) via multivariate Cox regression analysis....
The common adverse effects of linezolid for treating septic patients with gram-positive cocci is anemia and thrombocytopenia, which limit its clinical application.We determined the vitamin B6 adjunctive therapy on linezolid-associated cytopenias, retrospectively studied 75 who received at least 7 days treatment.Patients were divided into a treatment group (LTG; n = 41) that only combination (CTG; 34) both B6. Each was further subdivided those sepsis severe sepsis. patient had red blood cell...
Background: Coronavirus disease 2019 (COVID-19) has become a worldwide pandemic, affecting countries across the globe. With no current vaccine, treatment is still critical intervention for minimizing morbidity and preventing disease-specific mortality. This study aimed to assess clinical outcomes of critically ill COVID-19 patients using Tocilizumab provide recommendations with severe disease. Methods: was retrospective analysis medical records six admitted Third People's Hospital Shenzhen,...
Background Elderly multiple organ dysfunction syndrome (MODS) patients receiving invasive mechanical ventilation have poor prognosis in intensive care units (ICUs). We studied the usefulness of four commonly used severity scores and extrapulmonary factors that affected weaning to predict outcome such patients. Methods Clinical data 197 on admission ICUs (from January 2009 June 2012) were retrospectively. The Acute Physiology Chronic Health Evaluation (APACHE) II, APACHE III, Sample...
Linezolid-associated thrombocytopenia (LAT) leads to drug withdrawal associated with a poor prognosis. Some risk factors for LAT have been identified; however, the sample size of previous studies was small, data from elderly individuals are limited, and simple score scale not established predict at an early stage, making it difficult identify intervene in stage.In this single-center retrospective case-control study, we enrolled patients treated linezolid intensive care unit January 2015...
We describe a 24-year-old man with type 1 diabetes mellitus and cavitary lesion in the right upper lobe, caused by zygomycete. Surgical resection plus liposomal amphotericin B therapy was successful. discuss predisposing condition, clinical findings, diagnosis, treatment of pulmonary zygomycosis.
White smoke bomb exposure in the military setting could result organ injuries, which is uncommon and has been rarely described previous studies. The aim of this study to observe whether serum zinc levels are associated with liver function after white inhalation. Fifteen patients were subjects study. clinical manifestations, tests analysed. level was increased moderate or severe group (n = 4) compared that mild 11). four cases had delayed impairment an elevation alanine transaminase....
Pulmonary alveolar proteinosis (PAP) is an uncommon disease first reported by Rosen et al 1 in 1958, and characterized the accumulation of surfactant proteins phospholipids within spaces. Acquired PAP divided into two forms based on clinical features: idiopathic secondary PAP. Secondary to be associated with haematological malignancies, Pneumocystis carinii pneumonia inhalation silica or titanium, most frequent underlying malignancy. The exact incidence malignancies still obscure, since...
Objective:This study aimed to develop predictive models for sudden sensorineural hearing loss through deep belief network (DBN) and explore whether the model performances differ when adopting different outcome criteria. Method: 228 potential predictors involving clinical characteristics, audio logical data, serological parameters out of 1 220 hospitalized SSHL patients who were admitted from June 2008 December 2015 analyzed retrospectively. The data deafness classified into two or four...
The purpose of this study was to investigate the characteristics distortion product otoacoustic emissions (DPOAE) in patients with auditory neuropathy (AN). factors affecting DPOAE elicitation rate each frequency, ear and change first last diagnosis natural course were analyzed.
Intensive care unit (ICU) resources are inadequate for the large population in China, so it is essential physicians to evaluate condition of patients at admission. In this study, our objective was construct a machine-learning risk prediction model mortality respiratory intensive units (RICUs).This study involved 817 who made 1,063 visits and were admitted RICU from 2012 2017. Potential predictors such as demographic information, laboratory results, vital signs clinical characteristics...
Abstract Introduction The mortality rate of hospitalized patients with severe hospital-acquired pneumonia (SHAP) remains high. Empirical broad-spectrum antibiotic coverage and the misuse high-grade antibiotics could lead to emergence multi-drug even pandrug-resistant bacteria. In addition metagenomic next-generation sequencing (mNGS), microbiological rapid on-site evaluation (M-ROSE) might be a useful technique identify pathogens in early stage; however, effect M-ROSE guiding anti-infection...
Abstract Background Patients with severe infection often require careful fluid management. Intravenous linezolid can increase the volume, whereas oral effectively limit volume. However, differences in treatment effect and incidence of thrombocytopenia between intravenous patients remain unclear. Methods who received intensive care unit PLA General Hospital from December 2010 to 2020 were divided into an group according route administration, we further established PO PO-match by propensity...