A5062478578- Respiratory Support and Mechanisms
- Sepsis Diagnosis and Treatment
- Chronic Obstructive Pulmonary Disease (COPD) Research
- Neonatal Respiratory Health Research
- Nosocomial Infections in ICU
- Pulmonary Hypertension Research and Treatments
- Intensive Care Unit Cognitive Disorders
- Neonatal and Maternal Infections
- Metabolism and Genetic Disorders
- Respiratory viral infections research
- Inhalation and Respiratory Drug Delivery
- COVID-19 Clinical Research Studies
- Pneumonia and Respiratory Infections
- COVID-19 diagnosis using AI
- Congenital Diaphragmatic Hernia Studies
- Anesthesia and Neurotoxicity Research
- Metabolism, Diabetes, and Cancer
- Asthma and respiratory diseases
- Cardiac, Anesthesia and Surgical Outcomes
- Neonatal Health and Biochemistry
- Cancer, Stress, Anesthesia, and Immune Response
- Liver Disease and Transplantation
- Pleural and Pulmonary Diseases
- MicroRNA in disease regulation
- Acute Myocardial Infarction Research
Bethune International Peace Hospital
2014-2024
Chinese PLA General Hospital
2012-2022
First Affiliated Hospital of Bengbu Medical College
2021
Chinese People's Liberation Army
2014-2020
Jinan Maternity And Care Hospital
2014-2018
82th Hospital of Pla
2016
Fu Wai Hospital
2014
Chinese Academy of Medical Sciences & Peking Union Medical College
2014
People's Liberation Army No. 150 Hospital
2014
Nankai University
2014
Patients with COVID-19 in the intensive care unit (ICU) have a high mortality rate, and methods to assess patients' prognosis early administer precise treatment are of great significance.
Abstract Background The purpose of this study was to explore the diagnostic value soluble triggering receptor expressed on myeloid cells 1 (sTREM-1), procalcitonin (PCT), and C-reactive protein (CRP) serum levels for differentiating sepsis from SIRS, identifying new fever caused by bacteremia, assessing prognosis when occurred. Methods We enrolled 144 intensive care unit (ICU) patients: 60 with systemic inflammatory response syndrome (SIRS) 84 complicated at more than 48 h after ICU...
Abstract Cervical cancer (CC) is one of the most common malignancies in women. Paclitaxel front-line chemotherapeutic agent for treating CC. However, its therapeutic efficacy limited because chemoresistance, mechanism which remains poorly understood. Here, we used microRNA (miRNA) arrays to compare miRNA expression levels CC cell lines, HeLa and CaSki, with their paclitaxel resistance counterparts, HeLa/PR CaSki/PR. We demonstrate that miR-125a was significantly downregulated miRNAs...
Community-acquired pneumonia (CAP) is a prevalent and potentially life-threatening infection, has poor prognosis in aged patients. The objective of this study was to compare the potential admission N-terminal pro B-type natriuretic peptide (proBNP) levels scoring models [CURB-65, Pneumonia Severity Index (PSI), Acute Physiology Chronic Health Evaluation (APACHE) II scores] predict outcomes for patients with CAP admitted Intensive Care Unit (ICU), explore prognostic factors.Clinical data were...
Maple syrup urine disease (MSUD) is a rare metabolic disorder of autosomal recessive inheritance caused by decreased activity branched-chain α-ketoacid dehydrogenase complex (BCKD). Mutations in the three genes (BCKDHA, BCKDHB and DBT) are associated with MSUD. Here, we describe presenting symptoms, clinical course gene mutation analysis Chinese boy MSUD.Plasma amino acid was performed tandem mass spectrometry levels organic acids were measured gas chromatography-mass spectrometry. The...
OBJECTIVE: Vaporized perfluorocarbon (PFC) is a treatment for lung injury; this study investigated its mode of action and potential protective effects on other organs, which are unclear. METHODS: Acute injury was induced by lavage with artificial seawater in 32 female New Zealand White rabbits. Animals received either conventional mechanical ventilation (CMV), positive end-expiratory pressure under CMV (PEEP), vaporized PFC ventilation, or (PEEP + PFC). Histopathology the lung, small...
Background Elderly multiple organ dysfunction syndrome (MODS) patients receiving invasive mechanical ventilation have poor prognosis in intensive care units (ICUs). We studied the usefulness of four commonly used severity scores and extrapulmonary factors that affected weaning to predict outcome such patients. Methods Clinical data 197 on admission ICUs (from January 2009 June 2012) were retrospectively. The Acute Physiology Chronic Health Evaluation (APACHE) II, APACHE III, Sample...
To assess the value of wearable 12-lead electrocardiogram (ECG) devices in pre-hospital diagnosis acute ST segment elevation myocardial infarction (STEMI).This analysis was conducted among 441 patients selected from the''National ECG Network'', who used device with critical situation warning change between January 2019, and August, 2021.The general characteristics, response time complaints STEMI were analyzed.The accuracy compared clinician's interpretation ECGs AI by device.In 89 patients,...
Background Acute exacerbation of chronic obstructive pulmonary disease (AECOPD) is a common condition, which affects not only the quality life patients but also their prognosis. The purpose this study was to explore effects an inhaled salbutamol sulfate solution and inhalation suspension glucocorticoid budesonide that were atomized with heliox treat AECOPD. Methods Twenty-three AECOPD divided into treatment group (He/O 2 =70%/30%) control (N /O =70%/30%). administered by twice day for 7...
Background: Extracorporeal membrane oxygenation (ECMO) provides continuous extracorporeal respiration and circulation to patients with severe cardiopulmonary failure maintain life. ECMO is expensive takes up a lot of medical resources. However, the mortality rate treated still exceeds 40%. In this study, an early prediction model requirement outcome treatment was developed using data collected 0-24h after were admitted ICU 0-48h use. This aims prevent overuse reduce risk patient death...
<sec> <title>BACKGROUND</title> Patients with COVID-19 in the intensive care unit (ICU) have a high mortality rate, and methods to assess patients’ prognosis early administer precise treatment are of great significance. </sec> <title>OBJECTIVE</title> The aim this study was use machine learning construct model for analysis risk factors prediction among ICU patients COVID-19. <title>METHODS</title> In study, 123 Vulcan Hill Hospital were retrospectively selected from database, data randomly...
Objective: To investigate the effects of primary preventive treatment under endoscope for esophageal and gastric varices on bleeding rate its relevant factors. Methods: 127 cases with liver cirrhosis accompanied without history were included in endoscopic non-endoscopic group, respectively. Informed consent was obtained from both groups. Gastric (Lgf) (Leg) diagnosed according to LDRf classification criteria, corresponding scheme selected recommended principle this method.The incidence...
To investigate the protective effect of dexmedetomidine (Dex) against acute lung injury induced by intestinal ischemia-reperfusion (II/R) in rats and its on NLRP3 inflammasome activity.Thirty-two normal male SD were randomly divided into 4 groups (n=8): sham operation group, where superior mesenteric artery (SMA) was exposed only; II/R SMA occluded for 1 h followed reperfusion 2 h; Dex+II/R subjected to received intraperitoneal injection Dex before reperfusion; pretreatment operation. The...