A5015134731- Infant Nutrition and Health
- Total Knee Arthroplasty Outcomes
- Animal health and immunology
- Milk Quality and Mastitis in Dairy Cows
- Cancer-related molecular mechanisms research
- Respiratory Support and Mechanisms
- Osteoarthritis Treatment and Mechanisms
- Animal Diversity and Health Studies
- Protein Hydrolysis and Bioactive Peptides
- Neonatal Respiratory Health Research
- Hair Growth and Disorders
- Viral gastroenteritis research and epidemiology
- Meat and Animal Product Quality
- Proteins in Food Systems
- Ruminant Nutrition and Digestive Physiology
- Orthopaedic implants and arthroplasty
- Probiotics and Fermented Foods
- Knee injuries and reconstruction techniques
- Reproductive Physiology in Livestock
- Dermatology and Skin Diseases
- MicroRNA in disease regulation
- Cervical Cancer and HPV Research
- Reconstructive Surgery and Microvascular Techniques
- Genetic and phenotypic traits in livestock
- Chinese history and philosophy
Anhui Academy of Agricultural Sciences
2016-2025
Chinese Academy of Agricultural Sciences
2013-2025
Ministry of Agriculture and Rural Affairs
2019-2025
Institute of Animal Sciences
2015-2025
Animal Science Research Institute
2019-2025
Xinjiang Agricultural University
2024-2025
Beihang University
2025
Affiliated Hospital of Jining Medical University
2015-2024
Institute for Conflict Research
2024
Zimmer Biomet (Netherlands)
2024
To aid in unraveling diverse genetic and biological unknowns, a proteomic approach was used to analyze the whey proteome cow, yak, buffalo, goat, camel milk based on isobaric tag for relative absolute quantification (iTRAQ) techniques. This analysis is first produce data from above-mentioned animal species: 211 proteins have been identified 113 categorized according molecular function, cellular components, processes gene ontology annotation. The results of principal component showed...
This study was performed to investigate whether intensive antihypertensive treatment with achieved blood pressure ( BP ) ≤140/90 mm Hg, as compared standard ≤150/90 could further improve cardiovascular outcomes in Chinese hypertensive patients older than 70 years. A total of 724 participants were randomly assigned or treatment. After a mean follow‐up 4 years, the 135.7/76.2 Hg group and 149.7/82.1 group. The visit‐to‐visit variability systolic diastolic lower that Intensive treatment,...
Milk fat globules memebrane (MFGM)-enriched proteomes from Holstein, Jersey, yak, buffalo, goat, camel, horse, and human were extracted identified by an iTRAQ quantification proteomic approach. Proteomes data analyzed bioinformatic multivariate statistical analysis used to present the characteristic traits of MFGM proteins among studied mammals. The this study are also related research article "Proteomic characterization comparison mammalian milk globule analysis" in Journal Proteomics [1].
BACKGROUND:Osteoarthritis (OA) is the most common joint disease and characterized by progressive degeneration of articular cartilage. The molecular basis OA involves various factors has not been fully clarified. Autophagy a conserved catabolic process that cellular degradation through lysosomal machinery. MATERIAL AND METHODS:We found miRNA-411 regulates chondrocyte autophagy in targeting hypoxia-inducible factor 1 alpha (HIF-1α) identified related mechanism. condition C28/I2 cells was...
Abstract Casein micelles contribute to the physicochemical properties of milk and may also influence its functionality. At present, however, there is an incomplete understanding casein micelle associated proteins diversity among obtained from different species. Therefore, samples were collected seven dairy animals groups, fractions prepared by ultracentrifugation their constituent identified liquid chromatography tandem mass spectrometry. A total 193 distinct all preparations. Protein...
To investigate the incidence of incontinence-associated dermatitis (IAD) among patients in intensive care unit (ICU) and to identify potential risk factors establish a reference for clinical nursing work.Patients ICU are susceptible IAD. IAD is painful, reduces patient's quality life adds workload medical staff. However, associated with may differ between countries healthcare settings.Prospective cohort study METHODS: From November 2016 2017, prospective was conducted among109 three Class 3,...
Glycosylation of proteins has been implicated in various biological functions and received much attention; however, glycoprotein components inter-species complexity have not yet elucidated fully milk proteins. N-linked glycosylation sites glycoproteins fat globule membrane (MFGM) fractions were investigated by combining N-glycosylated peptides enrichment high-accuracy Q Exactive identification, to map the N-glycoproteome profiles Holstein Jersey cows, buffaloes, yaks, goats, camels, horses,...
Heat stress decreases milk yield and deleteriously alters composition. Reduced feed intake partially explains some of the consequences heat stress, but metabolic changes in mammary tissue liver associated with synthesis have not been thoroughly evaluated. In current study, protein abundance between heat-stressed cows ad libitum pair-fed thermal neutral were investigated using iTRAQ proteomic approach. Most differentially expressed proteins from involved Gene Ontology category process....
Hair fibre length is an important economic trait of rabbits in fur production. However, molecular mechanisms regulating rabbit hair growth have remained elusive. Here we aimed to characterise the skin traits and gene expression profiles short-hair long-hair by histological transcriptome analyses. Haematoxylin-eosin staining was performed observe structure rabbits. Compared that rabbits, a significantly longer anagen phase observed In addition, RNA sequencing, identified 951 genes were...
Abstract Periprosthetic joint infections (PJIs) have become the most catastrophic complication for patients after arthroplasty. Although previous studies found that many biomarkers good performance diagnosing PJI, early diagnosis remains challenging and a gold standard is lacking. This study aimed to investigate diagnostic accuracy of plasma fibrinogen (FIB) in detecting PJI compared other traditional biomarks (CRP, WBC ESR). A total 156 (including 57 99 non-PJI patients) who underwent...
The somatic cell count (SCC) is widely used to assess milk quality and diagnose intramammary infections. Several whey proteins have been shown correlate significantly with SCC are considered potential indicators of udder health. However, the relationship between has not fully elucidated. In this study, samples were grouped into five categories based on levels. Subsequently, identified using a label-free proteomics approach, differential abundance was validated through selected reaction...
Atherosclerosis is the main cause of ischemic stroke. It occurs as a condition that leads to thickening arterial blood vessel walls and narrowing vessels, which can seriously affect normal flow blood. Currently, detection stenosis relies on large-scale hospital equipment like computed tomography (CT) magnetic resonance imaging (MRI), require specialized technicians operate are not convenient for daily use. In addition, affects multiple parameters hemodynamics in field, relying single...
Free monosaccharides are important carbohydrates in milk, providing both basic and bioactive nutritional benefits; however, the content composition of free milk from different species still not well understood. The aim this study was to develop a highly sensitive accurate liquid chromatography (LC)-MS method for precise quantification 8 species, including human, cow, goat, sheep, yak, camel, horse, donkey. chromatographic conditions MS parameters were systematically optimized ensure high...
This study aimed to assess the effectiveness of fatty acid (FA) fingerprinting in distinguishing geographical origin milk and linking FA profiles with those forage. A total 66 bulk-tank samples corresponding forage were collected over 3 consecutive days from 22 dairy farms across western, eastern, southern China. The compositions analyzed using GC-MS, identifying 81 individual FA. Using orthogonal partial least squares discriminant analysis significance analysis, we identified significant...
Background Pulmonary vascular medial hypertrophy in hypoxic pulmonary arterial hypertension (PAH) is caused part by decreased apoptosis artery smooth muscle cells (PASMCs). Puerarin, an isoflavone purified from the Chinese medicinal herb kudzu, ameliorates chronic PAH animal models. Here we investigated effects of puerarin on human PASMCs (HPASMCs), and to determine possible underlying mechanisms. Methodology/Principal Findings HPASMCs were cultured for 24 h normoxia or hypoxia (5% O2)...