A5079628658- Dementia and Cognitive Impairment Research
- Cognitive Functions and Memory
- Neural and Behavioral Psychology Studies
- Alzheimer's disease research and treatments
- Aging and Gerontology Research
- Family Caregiving in Mental Illness
- Health, Environment, Cognitive Aging
- Psychosomatic Disorders and Their Treatments
- Neurological Disease Mechanisms and Treatments
- Nutritional Studies and Diet
- Genetics and Neurodevelopmental Disorders
- Identity, Memory, and Therapy
- Health disparities and outcomes
- Family Support in Illness
- Memory Processes and Influences
- Neuroendocrine regulation and behavior
- Diet and metabolism studies
- Neurological Disorders and Treatments
- Neural dynamics and brain function
- Functional Brain Connectivity Studies
- Memory and Neural Mechanisms
- Health, Medicine and Society
- Traumatic Brain Injury Research
- Olfactory and Sensory Function Studies
- Psychoanalysis and Psychopathology Research
Sorbonne Université
2014-2021
Université Paris Cité
2008-2021
Institut du Cerveau
2015-2021
Inserm
2018-2021
Assistance Publique – Hôpitaux de Paris
2017
Délégation Paris 5
2008-2017
Pitié-Salpêtrière Hospital
2017
Sorbonne Paris Cité
2017
Laboratoire de Psychopathologie et Processus de Santé
2014-2017
Columbia University Irving Medical Center
2015
Research increasingly suggests that subjective cognitive decline (SCD) in older adults, the absence of objective dysfunction or depression, may be a harbinger non-normative and eventual progression to dementia. Littl
Subjective cognitive decline (SCD) may result from many conditions, including Alzheimer's disease (AD).In this study, we searched for a specific pattern of SCD in asymptomatic individuals at risk AD.Cognitively normal older adults (N = 318) reporting and their informants were enrolled the INSIGHT-PreAD cohort. We examined relationship between six measures both scores AD neuroimaging markers (amyloid burden, hippocampal atrophy brain hypometabolism). An awareness index (ACDI) has been...
Background: Subjective cognitive decline (SCD) is increasingly considered promising to detect preclinical Alzheimer's disease. How SCD ascertained critical for determining its potential utility in identifying at-risk individuals, yet measures differ along several dimensions. Objective: We aimed examine the extent which reports of healthy elderly may be influenced by characteristics measures. investigated variations rates endorsement across different measures, including an open-ended...
Subjective cognitive decline (SCD) designates a self-reported despite preserved abilities. This study aims to explore, in older adults with SCD, the association between intensity of complaint and psychological factors including Young's early maladaptive schemas (EMSs) (i.e. enduring structures giving rise beliefs about oneself world), as well depression anxiety.Seventy-six subjects (69.22 years ± 6.1) intact functioning were recruited through an advertisement offering free participation...
While cognitive dissonance is an influential concept of social psychology, its relations with consciousness and episodic memory remain strongly debated. We recently used the free-choice paradigm (FCP) to demonstrate crucial role conscious previous choices on choice-induced preference change (CIPC). After choosing between two similarly rated items, subjects reevaluated chosen items as more attractive, rejected less attractive. However such a CIPC was present exclusively for that were...
Subjective cognitive decline (SCD) is considered an early aspecific clinical marker for Alzheimer's disease (AD). In this study, we wanted to search a specific pattern of SCD in asymptomatic individuals at risk AD. Cognitively normal older adults (n=318) reporting and their informants were enrolled the INSIGHT-PreAD cohort. Subjects performed 6 questionnaires assessing different aspects SCD. We examined relationship between these measures AD neuroimaging markers (amyloid burden assessed by...
There is considerable interest in Subjective Memory Complaint (SMC) as a potential indicator of preclinical Alzheimer's disease. However, the measures SMC vary with respect to several dimensions including time frame, comparison group that individuals are asked consider, and response options provided. The consistency which SMCs endorsed different contexts unknown. purpose this study was examine relationships between questions across questionnaires. 150 healthy older adults (MMSE> 27; mean...
Group cognitive-behavioural therapies (CBT) became, last decade, the intervention of choice in terms efficacy, cost/benefit balance and feasibility Alzheimer disease's (AD) family caregivers. There are mainly based on psycho-education problem solving sessions. However, clinically, benefit CBT remains weak about 25% Losada et al (2004) has shown that new programs including sessions exploration modification dysfunctional thoughts (DT) care were improving efficacy CBT, particularly lowering...
Subjective cognitive decline (SCD) is increasingly identified as a potential at-risk stage for Alzheimer's disease (AD). A key issue in SCD to identify the earliest clinical symptoms indicative of preclincal AD, when these subjects are considered be predominantly asymptomatic. Experiencing difficulties with performing instrumental activities daily living (IADL) potentially such an early symptom. Because amyloid one pathological changes objective current study investigate relationship between...