A5068279094- Reproductive Biology and Fertility
- Assisted Reproductive Technology and Twin Pregnancy
- Ovarian function and disorders
- Effects and risks of endocrine disrupting chemicals
- Sperm and Testicular Function
- Reproductive Health and Technologies
- Microplastics and Plastic Pollution
Shanghai First Maternity and Infant Hospital
2022-2024
Manual semen evaluation methods are subjective and time-consuming. In this study, a deep learning algorithmic framework was designed to enable non-invasive multidimensional morphological analysis of live sperm in motion, improve current clinical morphology testing methods, significantly contribute the advancement assisted reproductive technologies. We improved FairMOT tracking algorithm by incorporating distance angle same head movement adjacent frames, as well target detection frame IOU...
Frozen-thawed embryo transfer (FET) is thought to be associated with obstetric and neonatal complications after in vitro fertilization/intracytoplasmic single sperm injection (IVF/ICSI) treatment. The study aimed determine whether the endometrial preparation protocol an influencing factor for these complications.We conducted a retrospective cohort of 3,458 women who had singleton deliveries IVF/ICSI-FET treatment at Centre Reproductive Medicine Shanghai First Maternity Infant Hospital...
Microplastics (MPs) are pervasive environmental contaminants, resulting in unavoidable human exposure. This study identified MPs follicular fluid and investigated the specific mechanisms that adversely affect oocytes. of 44 infertile women undergoing assisted reproductive technology were measured using Raman microspectroscopy. Differential metabolites analyzed via untargeted metabolomics. Female mice exposed to polyethylene (PE) validate findings. MPs, particularly PE, exhibited highest...
Embryo selection in vitro fertilization–embryo transfer (IVF-ET) mostly relies on morphological assessment using a conventional microscope or the time-lapse monitoring system, which is not comprehensive. Inappropriate levels of reactive oxygen species (ROS) fertilization medium may cause damage to gametes, eventually leading adverse IVF outcomes. The present study aimed identify optimal oxidation–reduction level for outcomes by measuring static potential (sORP) highly accurate and sensitive...