A5014987687- Histone Deacetylase Inhibitors Research
- Genetics, Aging, and Longevity in Model Organisms
- Epigenetics and DNA Methylation
- Alzheimer's disease research and treatments
- Cell death mechanisms and regulation
- Neuroendocrine regulation and behavior
- Insect and Arachnid Ecology and Behavior
- CRISPR and Genetic Engineering
- Neurobiology and Insect Physiology Research
- Pluripotent Stem Cells Research
- Trace Elements in Health
- Phagocytosis and Immune Regulation
California University of Pennsylvania
2023-2024
Princeton University
2015
Abstract Alzheimer’s Disease (AD) is a disorder characterized by cognitive decline, neurodegeneration, and accumulation of amyloid plaques tau neurofibrillary tangles in the brain. Dysregulation epigenetic histone modifications may lead to expression transcriptional programs that play role either protecting against disease genesis or worsening pathology. One such modification, acetylation H3 lysine residue 27 (H3K27ac), primarily localized genomic enhancer regions promotes active gene...
ABSTRACT Social insects offer powerful models to investigate the mechanistic foundation of elaborate individual behaviors comprising a cooperative community. Workers leafcutter ant genus Atta provide an extreme example behavioral segregation among many phenotypically distinct worker types. We utilize complex system cephalotes test molecular underpinnings programming and, in particular, extent plasticity reprogramming. identify specific neuropeptides as mediators division labor A. , finding...
Abstract Alzheimer’s Disease (AD) is a disorder characterized by cognitive decline, neurodegeneration, and accumulation of amyloid plaques tau neurofibrillary tangles in the brain. Dysregulation epigenetic histone modifications may lead to expression transcriptional programs that play role either protecting against disease genesis or worsening pathology. One such modification, acetylation H3 lysine residue 27 (H3K27ac), primarily localized genomic enhancer regions promotes active gene...