- Leprosy Research and Treatment
- Mycobacterium research and diagnosis
- Botany, Ecology, and Taxonomy Studies
- Ethnobotanical and Medicinal Plants Studies
- Essential Oils and Antimicrobial Activity
- Pharmacology and Obesity Treatment
- Analytical Methods in Pharmaceuticals
- Public Health in Brazil
- Infectious Diseases and Tuberculosis
- Hematological disorders and diagnostics
- Natural product bioactivities and synthesis
- Tuberculosis Research and Epidemiology
- Traditional and Medicinal Uses of Annonaceae
- Healthcare and Environmental Waste Management
- Enzyme Catalysis and Immobilization
- Poisoning and overdose treatments
- Dialysis and Renal Disease Management
- Malaria Research and Control
- Acute Kidney Injury Research
- Insect Pest Control Strategies
- Plant Toxicity and Pharmacological Properties
- Sesquiterpenes and Asteraceae Studies
- Complementary and Alternative Medicine Studies
- Phytochemistry Medicinal Plant Applications
- Ocular Diseases and Behçet’s Syndrome
Universidade Federal do Oeste do Pará
2019-2025
Universidade Federal do Pará
2022
Instituto de Saúde
2019-2021
Universidade Federal da Paraíba
2015
Leprosy remains an important public health problem in some specific high-burden pockets areas, including the Brazilian Amazon region, where it is hyperendemic among children.We selected two elementary schools located areas most at risk (cluster of leprosy or census tract) to clinically evaluate their students. We also followed anti-PGL-I seropositive and seronegative individuals households for 2 years compare incidence both groups.Leprosy was detected 11 (8.2 %) 134 school children high...
Oral diseases are one of the biggest public health problems worldwide, caused by opportunistic pathogens such as Streptococcus mutans and Enterococcus faecalis. Cyperus articulatus (priprioca) is a plant conventionally used in traditional medicine Amazon region. However, little known about possible dentistry-related uses extracts from rhizomes solid waste generated extraction essential oils this vegetable. This study aimed to investigate chemical composition volatile compounds antimicrobial...
Diagnostic tests for leprosy are limited, especially to identify early cases. We performed active case findings of validate three potential antigen candidates and one molecular target. Cases were diagnosed by characteristic skin lesions, nerve enlargement, or sensation loss. Serum samples obtained from all subjects tested ELISA assess antibody titers Mycobacterium leprae specific antigens: NDO-BSA, LID-1, NDO-LID. Most the field cases on Mosqueiro Island, northern Brazil, also collected slit...
ABSTRACT Malaria is a disease of global tropical distribution, being endemic in more than 90 countries and responsible for about 212 million cases worldwide 2016. To date, the strategies used to eradicate this have been ineffective, without specific preventive measures such as vaccines. Currently, existing therapeutic arsenal limited has become ineffective against expansion artemisinin-resistant Plasmodium, demonstrating need studies that would allow development new compounds disease. In...
The number of new cases leprosy reported worldwide has remained essentially unchanged for the last decade despite continued global use free multidrug therapy (MDT) provided to any diagnosed patient. In order more effectively interrupt chain transmission, strategies will be required detect those with latent disease who contribute furthering transmission. To improve ability diagnose earlier in asymptomatic infected individuals, we examined combined two well-known biomarkers M . leprae...
Copaifera reticulata Ducke is a popularly known species as copaíba that widely spread throughout the Amazon region. The tree yields an oleoresin which extensively used in local traditional medicine mainly anti-inflammatory and antinociceptive agent. aim of present study was to assess potential this obtained from national forest central presented unusual chemical composition. composition volatile compounds analyzed by gas chromatography-mass spectrometry. acute toxicity assay performed with...
A produção maciça de resíduos saúde em território brasileiro tem aumentado e isso resultou diversos problemas diretos indiretos à humana ambiental tais como: perversão do solo consequentemente da água, proliferação doenças por vetores, contaminação gotículas ar poluições locais. O objetivo desta pesquisa foi identificar o descarte inadequado medicamentos seus impactos ao meio ambiente brasileiro. Este é um estudo exploratório que como finalidade a busca informações sobre uso impróprio seu no...
Malaria is an infectious and parasitic disease caused by protozoa of the genus Plasmodium, which affects millions people in tropical subtropical areas. Recently, there have been multiple reports drug resistance Plasmodium populations, leading to search for potential new active compounds against parasite. Thus, we aimed evaluate vitro antiplasmodial activity cytotoxicity hydroalcoholic extract Jucá (Libidibia ferrea) serial concentrations. was used form a freeze-dried extract. For assay,...
INTRODUÇÃO: Rourea induta Planch.é um arbusto de até quatro metros altura, comum no cerrado e nativo do Brasil.É conhecido popularmente como "chapeudinha", "pau-deporco" ou "campeira".O seu uso na medicina tradicional inclui o preparo remédios caseiros para fins
Introdução: A farmacovigilância é um instrumento usado para identificar, examinar e monitorar a ocorrência dos eventos adversos relacionados medicamentos utilizados por pacientes após o registro. Entretanto, falhas no processo de monitoramento pós-comercialização podem implicar em consequências à saúde humana. Objetivo: Relacionar os efeitos verificar as humana, identificando possíveis notificação reações adversas relacionadas (RAMs), através levantamento artigos realizado bases dados....