A5073306873- Lung Cancer Diagnosis and Treatment
- Global Cancer Incidence and Screening
- Lung Cancer Treatments and Mutations
- Cancer Immunotherapy and Biomarkers
- Chronic Obstructive Pulmonary Disease (COPD) Research
- Extracellular vesicles in disease
- COVID-19 and healthcare impacts
- COVID-19 Clinical Research Studies
- Long-Term Effects of COVID-19
- Interstitial Lung Diseases and Idiopathic Pulmonary Fibrosis
- SARS-CoV-2 and COVID-19 Research
- Radiomics and Machine Learning in Medical Imaging
- Inflammatory Biomarkers in Disease Prognosis
- Medical Imaging Techniques and Applications
- HER2/EGFR in Cancer Research
- Hepatocellular Carcinoma Treatment and Prognosis
- Cardiovascular Function and Risk Factors
- Autoimmune and Inflammatory Disorders
- Respiratory Support and Mechanisms
- Head and Neck Cancer Studies
- Effects of Radiation Exposure
- Nursing care and research
- Immune cells in cancer
- Heart Failure Treatment and Management
- Economic and Financial Impacts of Cancer
Instituto Nacional de Cancerología
2018-2024
Instituto Nacional de Cancerología
2024
Instituto Nacional de Cardiología
2024
Hospital Médica Sur
2022
Instituto Nacional de Enfermedades Respiratorias
2016
Radiation pneumonitis (RP) is a frequent complication of concurrent chemoradiotherapy (CCRT) and associated with severe symptoms that decrease quality life might result in pulmonary fibrosis or death. The aim this study to identify whether function test (PFT) abnormalities may predict RP non-small cell lung cancer (NSCLC) patients. A prospective multi-institutional was conducted locally advanced oligometastatic NSCLC All participants were evaluated at baseline, end CCRT, week 6, 12, 24, 48...
Immune-checkpoint inhibitors (ICIs) are an effective therapeutic strategy, improving the survival of patients with lung cancer compared conventional treatments. However, novel predictive biomarkers needed to stratify which derive clinical benefit because currently used and highly heterogenic histological PD-L1 has shown low accuracy. Liquid biopsy is analysis in body fluids represents a minimally invasive tool that can be monitor tumor evolution treatment effects, potentially reducing biases...
Immune checkpoint inhibitor-related pneumonitis (ICIP) is a potentially life threatening immune-related adverse event (irAE), especially in non-small cell lung cancer (NSCLC) patients. Currently, the potential for increased irAE patients who receive radiotherapy scarcely known, although connection between antitumor immune responses and irAEs has been suggested. In this study, we evaluated development of ICIP with prior radiotherapy, treated immunotherapy second-line.In retrospective trial,...
Accumulated evidence indicates that patients with lung cancer are a vulnerable population throughout the pandemic. Limited information is available in Latin America regarding impact of pandemic on medical care. The goal this study was to describe clinical and social effect COVID-19 thoracic ascertain outcomes those confirmed diagnosis.
Abstract The severe acute respiratory syndrome coronavirus 2 (SARS‐CoV‐2) causes disease 2019 (COVID‐19) and has been related to more than 7 million deaths globally since 2019. association of high levels IL‐6 with cases led the early evaluation anti‐IL6 inhibitor tocilizumab as a potential treatment, which unfortunately failed improve survival in many trials. Moreover, little is known about development COVID‐19 sequelae, biomarkers are needed understand anticipate these processes. Because...
Abstract Introduction Stigma in lung cancer patients may be associated with various negative outcomes such as increased psychosocial symptoms, severity of physical and act a barrier to medical help-seeking behavior. The Cataldo Lung Cancer Scale (CLCSS) is one the most widely used instruments for assessing health-related stigma patients. Objectives To determine psychometric properties CLCSS Mexican sample Methods A non-experimental, instrumental design was employed, using non-probabilistic...
Chronic heart failure continues to be one of the main causes impairment in functioning and quality life people who suffer from it, as well mortality our country around world.Mexico has a high prevalence risk factors for developing failure, such blood pressure, diabetes, obesity, which makes it essential have an evidence-based document that provides recommendations health professionals involved diagnosis treatment these patients.This establishes clinical practice guide (CPG) prepared at...
Proporcionar recomendaciones para la detección temprana de pacientes con alto riesgo desarrollar cáncer pulmón (CP) en el primer nivel atención y su referencia oportuna. Material métodos. Se realizó una búsqueda detallada evidencia científica disponible responder las preguntas investigación clínica se utilizó Panel Delphi modificado lograr un consenso entre expertos.Se generaron 14 siguiendo los estándares GPC. Conclusión. El CP representa problema salud pública México; por ello, esta guía...
La detección temprana de cáncer pulmonar (CP) en población alto riesgo tiene el potencial diagnosticar la enfermedad estadios tempranos y facilitar tratamiento oportuno con fin disminuir tasa mortalidad. En México, como otros países vías desarrollo, además del tabaquismo, exposición al humo leña se posiciona uno los principales factores para desarrollar CP, lo cual no ha considerado estudios tamizaje previamente publicados. Distintas interrogantes surgen relación quiénes son las personas que...
Immune dysregulation and cancer treatment may affect SARS-CoV-2 vaccination protection. Antibody production by B-cells play a vital role in the control clearance of virus. This study prospectively explores B-cell seroconversion following immunization healthy individuals non-small cell lung (NSCLC) patients undergoing oncological treatment. 92 NSCLC 27 individuals' blood samples were collected after receiving any COVID-19 vaccine. Serum mononuclear cells isolated, serum surrogate virus...
Abstract Background: Immune-checkpoint inhibitors (ICIs) have improved the clinical benefit of only a subset patients with advanced non-small cell lung cancer (NSCLC), since tissue PD-L1 has showed low predictive accuracy. We previously that extracellular vesicle (EV) identified durable responders to ICIs and radiomics analysis baseline CT scans EV model. Here, we aim validate this combination model identify non-responders ICIs. Methods: enrolled 3 cohorts patients, cohort (1) included 27...