A5089124460- Cancer Genomics and Diagnostics
- Genomics and Rare Diseases
- Ruminant Nutrition and Digestive Physiology
- Genetic factors in colorectal cancer
- Meat and Animal Product Quality
- Genomic variations and chromosomal abnormalities
- Fatty Acid Research and Health
- Medieval Architecture and Archaeology
- Molecular Biology Techniques and Applications
- Historical Art and Architecture Studies
- Genetic and phenotypic traits in livestock
- IoT and Edge/Fog Computing
- BRCA gene mutations in cancer
- Medical research and treatments
- Historical Studies in Science
- Water Resource Management and Quality
- Historical and socio-economic studies of Spain and related regions
- Digital Transformation in Industry
- Media, Journalism, and Communication History
- Libraries, Manuscripts, and Books
- Archaeological and Historical Studies
- Genomics and Phylogenetic Studies
- Genetic Associations and Epidemiology
- Epigenetics and DNA Methylation
- Environmental and Cultural Studies in Latin America and Beyond
Tempus Labs (United States)
2022-2023
Universidad de Sevilla
2002-2019
Universidad Politécnica de Madrid
2018
Stanford University
2017
Hospital Universitario de Valme
2013
College of San Mateo
2011
Universidad de Extremadura
2002
We are in front of a new digital revolution that will transform the way we understand and use services infrastructures. One key factors this is related to evolution Internet Things (IoT). Connected sensors be installed cities homes affecting daily life people providing them ways performing their activities. However, also affect business industry bringing IoT production processes what called Industry 4.0. Sensor-enabled manufacturing equipment allow real time communication, smart diagnosis...
Abstract The viability of conventional goat farms, such as the native Payoya dairy goat, could be improved by switching to organic production, but product quality needs ensured. present work assesses carcass and meat kids raised under grazing-based systems. Twenty-four (12 males, 12 females) were selected from each system (n = 48). slaughter live weight (8.52 vs. 8.28 kg), cold (4.44 4.29 kg) farm dressing percentage (51.7 50%) conventionally significantly higher than those kids. shoulder...
Modern IoT deployments do require considerable investments that might only be justified if the data being gathered could monetized, which leads to need for a digital marketplace. In many cases, provider of needs process it locally curation, aggregation, stream processing, etc. At same time, consumer interested in nearby data. This scenario resembles fog computing architecture where companies able, keeping under their control, securely make available other peer‐to‐peer fashion, without...
<h3>BACKGROUND:</h3> Research has provided evidence for the safety, feasibility, and efficacy of exercise training in patients with COPD. However, little is known about impact chronic respiratory failure due to kyphoscoliosis. We evaluated effect an program on capacity, muscle strength, dyspnea, quality-of-life indices subjects <h3>METHODS:</h3> The 34 were clinically stable, had been receiving nighttime home mechanical ventilation ≥ 6 months, randomly assigned group (<i>n</i> = 17) or...
Interest in the preservation of autochthonous breeds such as Payoya goat (dairy breed), raised using extensive or semi-extensive grazing, has also recently increased among Spanish farmers. A study possibilities transformation to organic production needs analyze quality their products, specially suckled kids. The objective this was evaluate fatty acid (FA) composition kids under and conventional grazing–based management system. Forty-eight were selected (12 males 12 females from each system)....
3620 Background: The incidence and mortality of early onset colorectal cancer (EOCRC), defined as CRC diagnosed prior to age 50, are rising, in contrast declining rates average (AOCRC). Epidemiologic trends for appear differ by race/ethnicity, which could be related part underlying differences tumor mutation gene expression. Previous research has used self-reported race/ethnicity categories, been shown missing or inaccurate, particularly highly admixed groups such Black Hispanic patients....
Genome-wide association studies (GWAS) have been successful in identifying common genetic variation reproducibly associated with disease. However, most variants confer very small risk and after meta-analysis of large cohorts a fraction expected heritability still remains unexplained. A possible explanation is that rare currently undetected by GWAS SNP arrays could contribute when present cases. This concept has spurred great interest exploring the role As cost sequencing continue to plummet,...
Interest in the preservation of autochthonous breeds such as Blanca Andaluza goat (meat breed), raised under grazing-based management, has recently increased among Spanish farmers. A study possibilities transformation to organic production needs analyze quality their products. The aim this was evaluate fatty acid (FA) composition muscle and adipose tissues kids conventional grazing–based management system. Twenty-four twin (12 males, 12 females) were selected from each FA profile determined...
River Information Services (RIS) are the European standard focused on improving inland navigation by providing a series of harmonized data services available for community. The RIS-compliant systems expected to improve safety, efficiency and environmental friendliness all accessible resources during through canals or rivers. Fiware is an open source framework one Connecting Europe Facility (CEF) building blocks. Its core provides tools aggregating from variety sources, generating shared...
10573 Background: The incidence and mortality of cancer vary widely across race ethnicity. This is attributed to an interplay socioeconomic factors, environmental exposures, genetic background. Cancer genomic studies have underrepresented minorities individuals non-European descent, thus limiting a comprehensive understanding disparities in the diagnosis, prognosis, treatment among these populations. Furthermore, social constructs ethnicity are far from precise categories understand...
Work with mentally handicapped people often raises the problem of communication difficulties. Several attempts have been made to provide alternatives in order improve relation between these persons and their environment. In most cases methods, based on graphical items, need continual attention by teachers allow subject interaction external world. Moreover such a manual method requires great deal effort adapt it different individuals. this work an open environment is proposed, oriented...
3138 Background: TMB is routinely reported in cancer patients tested with broad-panel next generation sequencing and has become a predictive biomarker associated response to checkpoint inhibitor (CPI) therapy. Sequencing of paired tumor normal specimens allows correction estimates patient-specific germline variants. When specimen unavailable, are corrected using variant annotations derived from population-scale surveys. Germline variants do not generate neoantigens, which the putative target...
<title>Abstract</title> Pharmacogenomic testing has emerged as an aid in clinical decision-making for psychiatric providers, but more data is needed regarding its utility practice and potential impact on patient care. In this cross-sectional study, we determined the real-world prevalence of pharmacogenomic actionability patients receiving Potential was based CYP2C19 CYP2D6 phenotypes, including allele-specific copy number variations (CNVs). Combined additionally incorporated phenoconversion...
Abstract Next Generation Sequencing is increasingly implemented as a diagnostic test to identify actionable mutations in cancer patient samples. However, for routine diagnostics, tumor DNA extracted from formalin-fixed, paraffin-embedded (FFPE) samples, which yields low quantity of damaged DNA. Inability accurately repair the ends these fragments impairs adapter ligation by standard double stranded methods. The resulting yield adapter-ligated introduces need whole-genome PCR amplification...