A5100722135- Gut microbiota and health
- Animal Nutrition and Physiology
- Enzyme Catalysis and Immobilization
- Ruminant Nutrition and Digestive Physiology
- Biofuel production and bioconversion
- Enzyme Production and Characterization
- Protein Hydrolysis and Bioactive Peptides
- Meat and Animal Product Quality
- Amino Acid Enzymes and Metabolism
- Microbial Metabolic Engineering and Bioproduction
- Clostridium difficile and Clostridium perfringens research
- Diet and metabolism studies
- Probiotics and Fermented Foods
- Traditional Chinese Medicine Analysis
- Genetic and phenotypic traits in livestock
- Biochemical effects in animals
- Pharmacological Effects of Natural Compounds
- Animal Behavior and Welfare Studies
- Genomics, phytochemicals, and oxidative stress
- Myasthenia Gravis and Thymoma
- Natural product bioactivities and synthesis
- Curcumin's Biomedical Applications
- Dietary Effects on Health
- Genetic Associations and Epidemiology
- Peanut Plant Research Studies
Henan Agricultural University
2013-2024
Ruijin Hospital
2024
Shanghai Jiao Tong University
2024
Nanjing University of Chinese Medicine
2024
Huazhong Agricultural University
2022-2024
Nanjing Drum Tower Hospital
2024
Xi'an Jiaotong University
2022-2024
Huaiyin Institute of Technology
2015-2023
Second Affiliated Hospital of Zhengzhou University
2023
Zhengzhou University
2023
Type 2 diabetes (T2D) is a major public health problem, and gut microbiota dysbiosis has been implicated in the emergence of T2D humans. Dietary interventions can indirectly influence status patients with type through their modulatory effects on intestinal microbiota. In recent years, fecal transplantation becoming familiar as new medical treatment that rapidly improve health. We conducted 90-day controlled open-label trial to evaluate improvement ability specially designed diet, diet...
Dietary fiber (DF) is increasingly thought to regulate diversity of piglet gut microbiota alleviate weaning stress in piglets. This study was conducted investigate the effects DF on growth performance piglets and composition their microbiota, as well interaction between short-chain fatty acids (SCFAs) A total 840 were allocated three dietary treatments consisting a control group (CG), an alfalfa meal (AG), commodity concentrated (OG) 30-day feeding trial. Gut mucosa feces samples used...
Although the direct effects of dietary fiber on gut microbiota composition have been studied extensively, systematic evaluation different sources health and inflammatory responses sows their offspring has rarely conducted. Excessive reactive oxygen species produced by overactive metabolic processes during late pregnancy lactation leads to increased endotoxin levels, disordered microbiota, decreased SCFA production, secretion proinflammatory factors, which in turn causes local inflammation...
Weaning of piglets is accompanied by intestinal inflammation, impaired barrier function, and microflora disorder. Regulating structure can directly or indirectly affect health host growth development. However, whether dietary fiber (DF) affects the inflammatory response function affecting its metabolites unclear. In this study, we investigated role in relieving immune stress maintaining homeostasis using with lipopolysaccharide (LPS)-induced injury as a model. DF improved morphology...
With increasing demand for high-quality pork, development of green and healthy feed finishing pigs is urgently needed. In this study, the effects mechanisms mulberry paper silages on growth performance, meat quality, intestinal health were explored. Intestinal microbiota profiled, microbially produced short-chain fatty acids (SCFAs) measured. The average daily gain (ADG) conversion rate (FCR) with not significantly different from those control. Meat quality as measured by pork marbling in...
ABSTRACT The gut microbiota contributes to skeletal muscle energy metabolism and is an indirect factor affecting meat quality. However, the role of specific microbes in fiber size chickens remains largely unknown. In this study, we first performed cecal transplantation from Chinese indigenous Jingyuan (JY) Arbor Acres (AA), determine effects on metabolism. Then, used metagenomics, gas chromatography, metabolomics analysis identify functional microbes. Finally, validated these regulating via...
To meet the demand for application of high activity and thermostable cellulases in production new-generation bioethanol from nongrain-cellulose sources, a hyperthermostable β-1,4-endoglucase Cel12B Thermotoga maritima was selected further modification by gene site-directed mutagenesis method present study, based on homology modeling rational design. As result, two recombinant enzymes showed significant improvement enzyme 77% 87%, respectively, higher than parental TmCel12B. Furthermore,...
Alginate lyases show great potential for industrial and medicinal applications, especially as an attractive biocatalyst the production of oligosaccharides with special bioactivities. A novel alginate lyase, AlyH1, from marine bacterium Vibrio furnissii H1, which has been newly isolated rotten seaweed, was purified characterized. The enzyme showed specific activity 2.40 U/mg. Its molecular mass 35.8 kDa. optimal temperature pH were 40 °C 7.5, respectively. AlyH1 maintained stability at...
Antibiotics are widely used in gastrointestinal diseases meat rabbit breeding, which causes safety problems for products. Dietary fiber can regulate the gut microbiota of rabbits, but mechanism improving quality is largely unknown. The objective this study was to evaluate effects adding different sources diets on growth performance, composition, and muscle metabolite composition rabbits. A total 18 New Zealand white rabbits similar weight (40 ± 1 day old) were randomly assigned beet pulp...
The aim of this study was to investigate the effect Bacillus subtilis var. natto N21 (BAC) and Saccharomyces cerevisiae Y10 (SAC) fermented liquid feed (FLF) during different incubation times on growth performance, relative organ weight, intestinal microflora, antioxidative status in Landes geese. Two hundred forty male geese (10 wk old) with BW 4.163 ± 0.108 kg were selected for a 3-wk trial randomly allotted 3 treatments according their replicates/treatment 8 geese/replicate). included 1)...
This study aimed to evaluate different roughages on fatting performance, muscle fatty acids, rumen fermentation and microbes of steers. Seventy-five Simmental crossbred steers were randomly divided into wheat straw group (WG), peanut vine (PG) alfalfa hay (AG), with 5 replicates each. The results showed a highest average daily gain lowest feed/gain ratio in AG ( P = 0.001). Steers fed had the marbling score n-3 polyunsaturated acid (PUFA), also NH 3 -N microbial protein (MCP) concentration...
The use of high-quality roughage to improve beef quality has become an important issue in China, as the country world's largest consumer. This study aimed evaluate effects different forage qualities (wheat straw vs alfalfa hay) on Simmental crossbreed cattle's meat quality, rumen fermentation and microbiota. AHG (Alfalfa hay group) improved ADFI (Average daily feed intake) ADG gain) cattle, meat-to-bone ratio EE (Ether extract). C18:3n3 C20:3n3 composition LD was significantly higher than...
Alfalfa saponins defend against oxidative stress by enhancing the antioxidant system and further inhibit cell apoptosis activating MAPK signaling pathway.
Background Nitrilase is an important member of the nitrilase superfamiliy. It has attracted substantial interest from academia and industry for its function converting nitriles directly into corresponding carboxylic acids in recent years. Thus played a crucial role production commercial chemical detoxification nitrile-contaminated wastes. However, conventional studies mainly focused on bacterial potential fungal been far being fully explored. Research gene expression will advance our...
Nitrilase-mediated biocatalysis has attracted substantial attention for its application in carboxylic acid production recent years. In the present study, fungus CA3-1 was isolated and identified as Gibberella intermedia based on morphology, 18S ribosomal DNA (rDNA), internal transcribed spacer (ITS) sequences. The enzymatic properties of G. resting cells were determined, optimum activity achieved at 40 °C with pH 7.6. half-lives nitrilase 30, 40, 50 231.1, 72.9, 6.4 h, respectively. This...
Bifunctional cellulases with β-glucosidase (Bgl1), exoglucanase (Exo5), and carbohydrate-binding modules (CBMs) from Caldicellulosiruptor saccharolyticus were fused to yield several recombinant plasmids, Bgl1-CBM-Exo5, Bgl1-2CBM-Exo5, Bgl1-3CBM-Exo5. The enzymes possessed both activities used improve the degradation efficiency of lignocellulosic biomass. optimal temperature Bgl1-3CBM-Exo5 was 70 °C, which same as Bgl1, other two 80 Exo5. pH 4 5, Exo5, but Bgl1 5.5. Compared Bgl1-CBM-Exo5...