A5060337576- Gut microbiota and health
- Animal Nutrition and Physiology
- Probiotics and Fermented Foods
- Polyamine Metabolism and Applications
- Clostridium difficile and Clostridium perfringens research
- Protein Hydrolysis and Bioactive Peptides
- Metabolomics and Mass Spectrometry Studies
- Pancreatic function and diabetes
- Innovative Microfluidic and Catalytic Techniques Innovation
- PI3K/AKT/mTOR signaling in cancer
- Biosensors and Analytical Detection
- Adipose Tissue and Metabolism
- Diet and metabolism studies
- Advanced Chemical Sensor Technologies
- Drug Transport and Resistance Mechanisms
- Clinical Nutrition and Gastroenterology
- Dietary Effects on Health
- Biochemical Analysis and Sensing Techniques
- Aquaculture disease management and microbiota
- Lipid metabolism and biosynthesis
- Muscle metabolism and nutrition
- Biopolymer Synthesis and Applications
- Animal Genetics and Reproduction
- Nutrition, Genetics, and Disease
- 14-3-3 protein interactions
Huazhong Agricultural University
2016-2025
Center of Hubei Cooperative Innovation for Emissions Trading System
2015-2024
Texas Tech University
2024
Universidade Federal de Santa Maria
2023
Zhejiang University
2003-2023
University of Zurich
2020-2022
Shanghai Zhangjiang Laboratory
2021
National Center for Gene Research
2019
Xinjiang Academy of Animal Science
2015-2016
Kerala Veterinary and Animal Sciences University
2012
Colonization of gut microbiota in mammals during the early life is vital to host health. The miniature piglet has recently been considered as an optimal infant model. However, less known about development piglets. Here, this study was conducted explore how develops weaned Congjiang In contrast relatively stabilized fungal community, bacterial community showed a marked drop alpha diversity, accompanied by significant alterations taxonomic compositions. relative abundances 24 genera...
Abstract Background The intestinal epithelial barrier confers protection against the invasion by pathogens and exposure to food antigens toxins. Growing studies have linked gut microbiota function. mining of microbes that facilitate function is urgently needed. Results Here, we studied a landscape microbiome seven pig breeds using metagenomics 16S rDNA gene amplicon sequencing. results indicated an obvious difference in between Congjiang miniature (CM) pigs (a native Chinese breed)...
Abstract Domestic pigs (Sus scrofa) are the leading terrestrial animals used for meat production. The gut microbiota significantly affect host nutrition, metabolism, and immunity. Hence, characterization of microbial structure function will improve our understanding resources mechanisms underlying host–microbe interactions. Here, we investigated microbiomes seven pig breeds using metagenomics 16S rRNA gene amplicon sequencing. We established an expanded reference catalog comprising 17 020...
Increased intestinal epithelial barrier function damages caused by early weaning stress have adverse effects on swine health and feed utilization efficiency. Probiotics emerged as the promising antibiotic alternatives used for damage prevention. Our previous data showed that Lactobacillus frumenti was identified a predominant in microbiota of weaned piglets. However, whether piglets regulated L. is still unclear. Here, received PBS vehicle or suspension (2 ml, 108 CFU/ml) containing oral...
Abstract Background Gut fungi are increasingly recognized as important contributors to host physiology, although most studies have focused on gut bacteria. Post-translational modifications (PTMs) of proteins play vital roles in cell metabolism. However, the contribution protein PTMs remains unclear. Mining that mediate and dissecting their mechanism urgently needed. Results We studied fungal communities 56 weaned piglets finishing pigs from seven pig breeds using internal transcribed spacer...
The interaction between nutrition and immunity plays a vital role in nutrient digestion, absorption, metabolism during poultry production. Recent studies showed that the gut microbiota contributes to development of intestinal mucosal immunity. However, mechanisms by which microbes regulate this process remain unclear.We compared Arbor Acre broilers (AA (lower immunity) Chinese native Wuliang Mountain Black-bone chickens (WLMB) (higher using 16S rDNA sequencing, transcriptomic analysis,...
A series of new targets containing 3 chiral elements central, orientational, and turbo chirality have been designed synthesized asymmetrically. The absolute configurations conformations these types were concurrently controlled by using sulfonimine auxiliary unambiguously determined x-ray diffraction analysis. These include alpha unnatural amino acid derivatives, which may play an important role for drug design, discovery, development. Three propellers framework are covalently connected to a C(sp
Dietary GlyGln supplementation improved gut microbiota dysbiosis and contributes towards the amelioration of ileum disorder in LPS-challenged weaned piglets.
ABSTRACT The gut microbiota contributes to skeletal muscle energy metabolism and is an indirect factor affecting meat quality. However, the role of specific microbes in fiber size chickens remains largely unknown. In this study, we first performed cecal transplantation from Chinese indigenous Jingyuan (JY) Arbor Acres (AA), determine effects on metabolism. Then, used metagenomics, gas chromatography, metabolomics analysis identify functional microbes. Finally, validated these regulating via...
The gut microbiome has great effects on the digestion, absorption, and metabolism of lipids. However, microbiota composition that can alter fat deposition meat quality pigs remains unclear. Here, we used Laiwu (LW) (a native Chinese breed with higher intramuscular fat) compared commercial crossbreed Duroc × (Landrace Yorkshire) (DLY) to investigate quality, especially in content. A total 32 DLY piglets were randomly allotted 4 groups transplanted fecal from healthy LW pigs. results indicated...
Lysine crotonylation as a protein post-translational modification regulates diverse cellular processes and functions. However, the role of in nutrient signaling pathways remains unclear. Here, we find positive correlation between global levels leucine-deprivation-induced autophagy. Crotonylome profiling identifies many crotonylated proteins regulated by leucine deprivation. Bioinformatics analysis dominates 14-3-3 leucine-mediated crotonylome. Expression 14-3-3ε crotonylation-deficient...
Abstract Gut microbiome changed dramatically during pregnancy and played important roles in metabolic status reproductive endocrinology mammals. However, investigating the functional microbiota metabolites to improve performance understanding host–microbiota interaction are still arduous tasks. This study aims reveal dominant strains that performance. We analyzed fecal composition of higher yield Chinese pig breed Meishan (MS) sows lower but widespread raised hybrid Landrace × Yorkshire (L...
Dairy cow mastitis is a common and prevalent disease arose by various complicated pathogeny, which poses serious threat to the health of cows, safety dairy product economic benefits for pastures. Due high stealthiness long incubation period, subclinical (SM) cows causes enormous losses. Besides infection exogenous pathogenic microorganisms, previous studies demonstrated that gastrointestinal microbial dysbiosis one crucial occurrence development based on theory entero-mammary axis. Whereas,...