David Gritsch

ORCID: 0000-0003-0138-2357
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About
Contact & Profiles
Research Areas
  • Glioma Diagnosis and Treatment
  • Acute Ischemic Stroke Management
  • Brain Metastases and Treatment
  • Mosquito-borne diseases and control
  • CNS Lymphoma Diagnosis and Treatment
  • Peptidase Inhibition and Analysis
  • Systemic Lupus Erythematosus Research
  • Melanoma and MAPK Pathways
  • Autoimmune Neurological Disorders and Treatments
  • Infectious Encephalopathies and Encephalitis
  • Peripheral Neuropathies and Disorders
  • Multiple Sclerosis Research Studies
  • Protein Tyrosine Phosphatases
  • Traumatic Brain Injury and Neurovascular Disturbances
  • Renal and Vascular Pathologies
  • Polyomavirus and related diseases
  • Cardiac tumors and thrombi
  • Vascular anomalies and interventions
  • Venous Thromboembolism Diagnosis and Management
  • Lymphoma Diagnosis and Treatment
  • Cerebrovascular and genetic disorders
  • Moyamoya disease diagnosis and treatment
  • Pharmacological Effects and Toxicity Studies
  • Migraine and Headache Studies
  • Blood Pressure and Hypertension Studies

Harvard University
2022-2024

Massachusetts General Hospital
2022-2024

Mayo Clinic in Arizona
2019-2023

Mass General Brigham
2023

WinnMed
2020-2022

Vall d'Hebron Hospital Universitari
2022

Mayo Clinic Hospital
2022

Mayo Clinic in Florida
2020-2022

Neurology, Inc
2021

Importance West Nile virus (WNV) is the leading cause of human arboviral disease in US, peaking during summer. The incidence WNV, including its neuroinvasive form (NWNV), increasing, largely due to expanding distribution vector, Culex mosquito, and climatic changes causing heavy monsoon rains. However, distinct characteristics outcomes NWNV individuals who are immunosuppressed (IS) not IS remain underexplored. Objective To describe compare clinical radiographic features, treatment responses,...

10.1001/jamanetworkopen.2024.4294 article EN cc-by-nc-nd JAMA Network Open 2024-03-28

Introduction Limited data exist on brain MRI enhancement in myelin-oligodendrocyte-glycoprotein (MOG) antibody-associated disease (MOGAD) and differences from aquaporin-4-IgG-positive-neuromyelitis-optica-spectrum-disorder (AQP4+NMOSD), multiple sclerosis (MS). Methods In this retrospective observational study, we identified 122 Mayo Clinic MOGAD patients (1 January 1996–1 July 2020) with cerebral attacks. We explored patterns using a discovery set (n=41). assessed frequency Expanded...

10.1136/jnnp-2023-331137 article EN Journal of Neurology Neurosurgery & Psychiatry 2023-05-23

<h3>Background and Objectives</h3> SM is recognized as a complication of migraine in which pain and/or associated symptoms are unremitting debilitating for more than 72 hours. The epidemiology the general population not known. aim this study to determine incidence, recurrence rate, clinical associations status migrainosus (SM) care-seeking residents Olmsted County, Minnesota. <h3>Methods</h3> Rochester Epidemiology Project was used identify incident cases according <i>International...

10.1212/wnl.0000000000201382 article EN Neurology 2022-09-29

Introduction: Reversible cerebral vasonstriction syndrome (RCVS) is an increasingly recognized clinical and radiologic syndrome. However, it has been rarely reported in the setting of novel coronavirus disease-2019 (COVID-19) infection or sarcomatous tumors. RCVS might be initial manifestations COVID-19 noncatecholamine producing masses including sarcoma. Case Report: A 44-year-old male who developed COVID-19–related symptoms followed by rapid onset severe headaches persistently elevated...

10.1097/nrl.0000000000000387 article EN The Neurologist 2021-11-30

Background: Combined PD-1/PD-L1 and CTLA-4 immune checkpoint inhibition for the has been shown to produce superior results in treatment of malignant melanoma when compared monotherapy. However, patients with intracranial disease were excluded from these studies given their poor prognosis. Objective: The objective this study was critically assess current evidence supporting co-administration inhibitors brain metastases. Methods: addressed through development a appraised topic that included...

10.1097/nrl.0000000000000439 article EN The Neurologist 2022-07-12

There is considerable controversy surrounding the optimal use of sedation in patients with acute ischemic stroke undergoing mechanical thrombectomy. Several retrospective studies have favored conscious (CS) over general anesthesia (GA) terms functional outcomes and mortality. Recent data from randomized controlled trials has challenged this view.The aim was to critically assess current evidence regarding CS versus GA thrombectomy for stroke.The objective addressed through development a...

10.1097/nrl.0000000000000318 article EN The Neurologist 2021-03-01

Introduction: Patent foramen ovale is a common congenital cardiac abnormality. An association with acute ischemic stroke well described. Extension of renal cell carcinoma (RCC) into the adjacent veins common. Surgical resection felt to be an effective approach treatment, even in setting extensive venous involvement. Case Report: A 55-year-old woman recently diagnosed right mass and cavoatrial tumor thrombus was transferred our facility for surgical resection. She subsequently underwent open...

10.1097/nrl.0000000000000276 article EN The Neurologist 2020-09-01

Wednesday, April 29April 14, 2020Free AccessDPPX autoimmune encephalitis presenting with chronic diarrhea, multidirectional nystagmus, opsoclonus and prominent hyperekplexia (5154)Karissa Arca, Amir Abdallah, David Gritsch, Benzion Blech, Andrew McKeon, Jonathan CarterAuthors Info & AffiliationsApril 2020 issue94 (15_supplement)https://doi.org/10.1212/WNL.94.15_supplement.5154 Letters to the Editor

10.1212/wnl.94.15_supplement.5154 article EN Neurology 2020-04-14

Organ-specific and nonorgan-specific autoimmune diseases commonly coexist with aquaporin-4 antibody (AQP4-IgG)-positive neuromyelitis optica spectrum disorder (NMOSD).We report an unusual case in which a young woman known systemic lupus erythematosus (SLE) was discovered to be AQP4-IgG seropositive when she developed simultaneous severe longitudinally extensive transverse myelitis, reversible intracranial vasculopathy, cutaneous vasculitis, myocarditis.We discuss the pathogenic mechanisms...

10.1212/nxi.0000000000000956 article EN cc-by-nc-nd Neurology Neuroimmunology & Neuroinflammation 2021-01-19

Objective: This is the first reported case of intraoperative paradoxical embolism in setting renal cell carcinoma with cavoatrial extension and patent foramen ovale. Background: Patent ovale a common congenital cardiac abnormality. An association acute ischemic stroke, secondary to venous blood clots, well described. Extension into adjacent veins common. Surgical resection felt be an effective approach treatment, even extensive involvement. Design/Methods: A report. Results: 55-year-old...

10.1212/wnl.94.15_supplement.1084 article EN Neurology 2020-04-14

Objective: NA Background: The number of immunocompromised individuals continues to rise in the United States, part given increasing solid organ and stem cell recipients. Despite increased risk West Nile virus encephalitis (WNVE) these individuals, data on radiographic other clinical features outcomes is limited. Design/Methods: We retrospectively reviewed clinical, laboratory, neuroimaging findings four patients with WNVE, that were treated at Mayo Clinic Arizona between June September 2019....

10.1212/wnl.94.15_supplement.5318 article EN Neurology 2020-04-14

Introduction: Hirayama disease is a rare neuromuscular disorder characterized by abnormal forward displacement of the cervical spinal cord, resulting in focal ischemic changes anterior horn cells. Case Report: A 15-year-old male presented with 6 months progressive right upper extremity weakness. Electromyography/nerve conduction study indicated chronic neurogenic process involving C8-T1 myotome. Cervical spine magnetic resonance imaging neutral position demonstrated minor disk bulges without...

10.1097/nrl.0000000000000447 article EN The Neurologist 2022-05-20
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