A5069184947- Transplantation: Methods and Outcomes
- Mechanical Circulatory Support Devices
- Congenital Heart Disease Studies
- Cardiac Structural Anomalies and Repair
- Renal Transplantation Outcomes and Treatments
- Adolescent and Pediatric Healthcare
- Organ Transplantation Techniques and Outcomes
- Heart Failure Treatment and Management
- Family and Patient Care in Intensive Care Units
- Congenital Diaphragmatic Hernia Studies
- Cardiovascular Issues in Pregnancy
- Cardiac Arrhythmias and Treatments
- Cardiac Valve Diseases and Treatments
- Cardiac Arrest and Resuscitation
- Viral Infections and Immunology Research
- Gestational Trophoblastic Disease Studies
- Systemic Lupus Erythematosus Research
- South Asian Studies and Conflicts
- Hemodynamic Monitoring and Therapy
- Contemporary Sociological Theory and Practice
- Family and Disability Support Research
- Vascular anomalies and interventions
- Cardiac, Anesthesia and Surgical Outcomes
- Ectopic Pregnancy Diagnosis and Management
- Congenital heart defects research
University of Florida
2016-2025
University of Florida Health
2017-2025
Florida College
2014-2025
University of Miami Hospital
2016-2023
UF Health Shands Hospital
2015-2023
American Academy of Dermatology
2023
Jacobs (United States)
2023
Queensland Health
2023
Institute of Post Graduate Medical Education and Research
2004-2022
Medical College and Hospital, Kolkata
2004-2022
Studies have demonstrated that angiotensin-converting enzyme 2 (ACE2) plays a protective role against lung diseases, including pulmonary hypertension (PH). Recently, an antitrypanosomal drug, diminazene aceturate (DIZE), was shown to exert "off-target" effect of enhancing the enzymatic activity ACE2 in vitro.To evaluate pharmacological actions DIZE experimental models PH.PH induced male Sprague Dawley rats by monocrotaline, hypoxia, or bleomycin challenge. Subsets animals were simultaneously...
Abstract Mitochondrial trifunctional protein deficiency is a long-chain fatty acid disorder that may include manifestations of severe cardiomyopathy and arrhythmias. The pathophysiology for the presentation unclear but an indicator worse outcomes. Triheptanoin, synthetic medium chain triglyceride, has been reported to reverse in some individuals, there limited literature cases. We describe neonatal onset disease whose clinical course was not improved despite mechanical support triheptanoin.
Medication adherence and timing of doses remains a challenge for adolescent patients following heart transplant. Mobile technology promotion efforts offer new avenues direct observation medication timeliness medication-taking behavior. The study explores posttransplant maintenance, highlighting the importance consistent dose with tacrolimus. use directly observed therapy (DOT) via mobile health app was examined as method real-time monitoring, offered platform to upload videos themselves...
Abstract Objectives Prediction of post-transplant health outcomes and identification key factors remain important issues for pediatric transplant teams researchers. Outcomes research has generally relied on general linear modeling or similar techniques offering limited predictive validity. Thus far, data-driven machine learning (ML) approaches have had application success in research. The purpose the current study was to examine ML models predicting hospitalization a sample kidney, liver,...
Objective We explore shared decision making (DM) in guardians of children with heart disease by assessing the desired weight influence on DM and factors that may alter relative parent or medical team influence. Methods Guardians patients <21 years admitted >1 week paediatric cardiac intensive care unit (PCICU) were recruited. Twelve vignettes designed including technical (antibiotic selection, intubation, peripherally inserted central catheter placement, ventricular assist device...
Abstract Medication non-adherence remains a significant challenge for adolescent heart transplant recipients. Building on the success of pilot intervention study, herein we describe protocol follow-up randomised control trial using mobile video directly observed therapy, featuring several innovations, to promote medication adherence in multi-centre sample patients.
Background Infants with heart failure remain at significant risk for wait list mortality, despite mechanical circulatory support (MCS). It is unclear if the outcomes are influenced by modality of or underlying diagnosis. We sought to compare infants <10 kg, focusing on and Methods Results Using Pediatric Heart Transplant Society database, we evaluated survival following first MCS device in children kg who were listed transplant between 2010 2018. There 2049 predominant diagnosis being...
This series describes three adolescent females who presented with chest pain and ventricular dysfunction related to acute coronary ischemia secondary Takayasu's arteritis varied courses of disease progression leading a diverse range therapies including cardiac transplantation. While is rare in childhood, it should be strongly considered any female presenting systemic inflammation consistent myocardial infarction. A high index suspicion can lead early detection aggressive management the...
Hemophilia is a common X-linked recessive coagulopathy causing recurrent bleeding into the synovial joints and results in articular periarticular abnormalities. To our knowledge, this first comprehensive study aimed at studying clinico-radiological joint score evaluation hemophilic arthropathy children from developing country its possible impact on quality of life.In hospital-based, prospective, descriptive study, all presenting to pediatric rheumatology clinic were studied. The physical...