A5080167839- Mechanical Circulatory Support Devices
- Cardiac Structural Anomalies and Repair
- Transplantation: Methods and Outcomes
- Cardiac Arrest and Resuscitation
- Congenital Heart Disease Studies
- Cardiomyopathy and Myosin Studies
- Renal Transplantation Outcomes and Treatments
- Viral Infections and Immunology Research
- Cardiac Arrhythmias and Treatments
- Atrial Fibrillation Management and Outcomes
- Cardiac pacing and defibrillation studies
- Neurogenetic and Muscular Disorders Research
- Ethics and Legal Issues in Pediatric Healthcare
- Palliative Care and End-of-Life Issues
- Cardiovascular Effects of Exercise
- Organ Donation and Transplantation
- Cardiac electrophysiology and arrhythmias
- Organ Transplantation Techniques and Outcomes
- Diversity and Career in Medicine
- Pulmonary Hypertension Research and Treatments
- Mentoring and Academic Development
- Heart Failure Treatment and Management
- Long-Term Effects of COVID-19
- Mitochondrial Function and Pathology
- Genetics and Physical Performance
Lurie Children's Hospital
2018-2025
Northwestern University
2018-2025
Children's Hospital of Philadelphia
2024
Morgan Stanley Children's Hospital
2016-2019
Columbia University Irving Medical Center
2016-2019
New York Hospital Queens
2018-2019
NewYork–Presbyterian Hospital
2018-2019
UCLA Medical Center
2019
Columbia University
2016
To clarify the clinical characteristics and outcomes of children with SCN5A-mediated disease to improve their risk stratification. A multicentre, international, retrospective cohort study was conducted in 25 tertiary hospitals 13 countries between 1990 2015. All patients ≤16 years age diagnosed a genetically confirmed SCN5A mutation were included analysis. There no restriction made based on diagnosis. total 442 {55.7% boys, 40.3% probands, median age: 8.0 [interquartile range (IQR) 9.5]...
Abstract There is considerable variability in donor acceptance practices among adult heart transplant providers; however, pediatric data are lacking. The aim of this study was to assess professionals. authors generated a survey investigate clinicians’ practices. This distributed all members the ISHLT Pediatric Council April 2018. A total 130 providers responded from 17 different countries. wide range acceptable criteria for potential donors. These included optimal donor‐to‐recipient weight...
Abstract Background: Patients with Fontan failure are high-risk candidates for heart transplantation and other advanced therapies. Understanding the outcomes following initial consultation can help define appropriate timing of referral care. Methods: This is a survey study providers seeing any patient Part 1 captured data on clinical characteristics at time consultation, 2, completed 30 days later, (death, transplant evaluation outcome, interventions). were classified as “too late” (death or...
BackgroundThe HeartWare ventricular assist device (HVAD) was discontinued in July 2021. The aim of this study is to describe the impact discontinuation HVAD had on pediatric utilization and outcomes.MethodsThe Advanced Cardiac Therapies Improving Outcomes Network (ACTION) registry queried for type VAD outcomes/adverse event rates patients with a body surface area 0.7-1.4 m2. Results were compared from before after All implanted reported determine overall outcomes these define who remains...
Abstract Background The relationship between histopathologic and molecular (“MMDx”®) assessments of endomyocardial biopsy (EMB) serum donor‐derived cell‐free DNA (ddcfDNA) in acute rejection (AR) assessment following pediatric heart transplantation (HT) is unknown. Methods EMB sent for MMDx histopathology from November 2021 to September 2022 were reviewed. results compared. DdcfDNA obtained ≤1 week prior compared with results. discrimination ddcfDNA AR was assessed using receiver‐operating...
Abstract Background Minimal data exist on clinical decision‐making in VAD implantation pediatrics. This study aims to identify areas of consensus/variability among pediatric physicians determining eligibility and factors that guide decision‐making. Methods An 88‐item survey with vignettes was sent 132 HT cardiologists surgeons at 37 centers. Summary statistics are presented for the variables assessed. Results Total respondents were 65 (72% cardiologists, 28% surgeons) whose centers implanted...
Data on ventricular assist device (VAD) outcomes in infants with stage 1 single ventricle (SV) palliation are limited. We examined the Advanced Cardiac Therapies Improving Outcomes Network (ACTION) registry for of pre/poststage SV patients undergoing VAD implantation between March 2018 and October 2020. collected from 32 centers major adverse events undergo central adjudication. During study period, 30 underwent implant median age 0.9 months (range 0.1-25) weight 3.7 kg (2.4-17). Preimplant...
BACKGROUND: DSP cardiomyopathy is a distinct subset of arrhythmogenic cardiomyopathy, reported primarily in adults, that has predominantly left ventricular involvement and features myocarditis. Clinical characteristics, risk stratification, management pediatric patients with variants are not well known. We sought to identify phenotypic prognosis pathogenic or likely variants. METHODS: Multicenter, retrospective study <21 years age from 6 tertiary hospitals. RESULTS: Thirty-four patients,...