A5029773468- Photodynamic Therapy Research Studies
- Nonmelanoma Skin Cancer Studies
- Skin Protection and Aging
- Wound Healing and Treatments
- Plasma Applications and Diagnostics
- Dermatologic Treatments and Research
- Nanoplatforms for cancer theranostics
- Medicine and Dermatology Studies History
- Cutaneous lymphoproliferative disorders research
- Cutaneous Melanoma Detection and Management
- Dermatology and Skin Diseases
- Burn Injury Management and Outcomes
- Autoimmune Bullous Skin Diseases
- Systemic Sclerosis and Related Diseases
- Medical and Health Sciences Research
- Acne and Rosacea Treatments and Effects
- Nail Diseases and Treatments
- Eosinophilic Disorders and Syndromes
- Cancer and Skin Lesions
- Autoimmune and Inflammatory Disorders
- Psoriasis: Treatment and Pathogenesis
- Genital Health and Disease
- Hematopoietic Stem Cell Transplantation
- Mast cells and histamine
- Dermatological and Skeletal Disorders
University Hospital Regensburg
2015-2024
University of Regensburg
2006-2020
In-Q-Tel
2013
University Hospital of Zurich
2012
University of Zurich
2012
University of Göttingen
2008
University Hospital Heidelberg
2008
University Medical Center Hamburg-Eppendorf
2008
University Medical Center Freiburg
2008
Universität Ulm
2008
Journal Article A first prospective randomized controlled trial to decrease bacterial load using cold atmospheric argon plasma on chronic wounds in patients Get access G. Isbary, Isbary Departments of Dermatology, Allergology and Environmental Medicine Georg Isbary. E‐mail: dr.isbary@googlemail.com Search for other works by this author on: Oxford Academic Google Scholar Morfill, Morfill Max Planck Institute Extraterrestrial Physics, Garching, Germany H.U. Schmidt, Schmidt Microbiology,...
Journal Article Successful and safe use of 2 min cold atmospheric argon plasma in chronic wounds: results a randomized controlled trial Get access G. Isbary, Isbary Department Dermatology, Allergology Environmental Medicine, Hospital Munich Schwabing, Koelner Platz 1, D‐80804 Munich, Germany Georg Isbary. E‐mail: dr.isbary@googlemail.com Search for other works by this author on: Oxford Academic Google Scholar J. Heinlin, Heinlin University Regensburg, T. Shimizu, Shimizu Max Planck Institute...
Cold atmospheric plasma (CAP) has the potential to interact with tissue or cells leading fast, painless and efficient disinfection furthermore positive effects on wound healing regeneration. For clinical implementation it is necessary examine how CAP improves which molecular changes occur after treatment. In present study we used second generation MicroPlaSter ß® in analogy current standard (2 min treatment time) order determine induced by using vitro cell culture studies human fibroblasts...
Abstract Topical photodynamic therapy (PDT) is a widely approved for actinic keratoses, Bowen's disease (squamous cell carcinoma in situ ), superficial and certain thin basal carcinomas. Recurrence rates when standard treatment protocols are used typically equivalent to existing therapies, although inferior surgery nodular carcinoma. PDT can be both as lesional field therapies has the potential delay/reduce development of new lesions. A protocol using daylight treat keratoses practised, with...
Objective. Systemic sclerosis (SSc) is a rare, heterogeneous disease, which affects different organs and therefore requires interdisciplinary diagnostic therapeutic management. To improve the detection follow-up of patients presenting with disease manifestations, an registry was founded contributions from subspecialties involved in care SSc.
Despite of the approval Photofrin® in various countries, chemically defined sensitizers for photodynamic therapy (PDT) are still needed absorption light infrared spectrum, which provides a maximal penetration into tissue. Therefore, both efficacy and mechanism action clinically approved dye indocyanine green (ICG) laser irradiation were investigated vitro. For investigation phototoxic effects, HT-29 cells incubated 24 h prior to by using different concentrations ICG (10–500 μM). In each...
Over the past few years, application of cold atmospheric plasma (CAP) in medicine has developed into an innovative field research rapidly growing importance. One promising new medical CAP is cancer treatment. Different studies revealed that may potentially affect cell cycle and cause apoptosis or necrosis tumor cells dependent on device doses. In this study, we used a novel hand-held battery-operated utilizing surface micro discharge (SMD) technology for production air consequently analysed...
In the last twenty years new antibacterial agents approved by U.S. FDA decreased whereas in parallel resistance situation of multi-resistant bacteria increased. Thus, community and nosocomial acquired infections resistant led to a decrease efficacy standard therapy, prolonging treatment time increasing healthcare costs. Therefore, aim this work was demonstrate applicability cold atmospheric plasma for decolonisation Gram-positive (Methicillin-resistant Staphylococcus aureus (MRSA),...
Topical photodynamic therapy (PDT) is a widely approved for actinic keratoses, squamous cell carcinoma in-situ, superficial and certain thin basal carcinomas. Recurrence rates are typically equivalent to existing therapies, although inferior surgery nodular carcinoma. PDT can be used both as lesional or field has the potential delay/reduce development of new lesions. also been studied its place in treatment of, well prevent, skin cancers immune-suppressed patients, sustained clearance lower...
Pyoderma gangrenosum (PG) is a rarely diagnosed ulcerative neutrophilic dermatosis with unknown origin that has been poorly characterized in clinical studies so far. Consequently there have significant discussions about its associated factors and comorbidities. The aim of our multicenter study was to analyze current data from patients dermatologic wound care centers Germany order describe comorbidities PG.Retrospective investigation PG Germany.We received 259 20 different Germany. Of these...
Abstract Cold atmospheric plasma has already been shown to decrease the bacterial load in chronic wounds. However, until now it is not yet known if treatment can also improve wound healing. We aimed assess impact of cold argon on process donor site Forty patients with skin graft sites upper leg were enrolled our study. The divided into two equally sized areas that randomly assigned receive either or placebo (argon gas) for 2 minutes. Donor healing was evaluated independently by blinded...
The field cancerization concept in photodamaged patients suggests that the entire sun-exposed surface of skin has an increased risk for development (pre)-malignant lesions, mainly epithelial tumours. Topical photodynamic therapy (PDT) is a noninvasive therapeutic method multiple actinic keratosis (AK) with excellent outcome.To evaluate clinical, histological and immunohistochemical changes human after sessions PDT methyl-aminolaevulinate (MAL).Twenty-six AK on face received three consecutive...
Abstract In addition to approved indications in non‐melanoma skin cancer immunocompetent patients, topical photodynamic therapy ( PDT ) has also been studied for its place the treatment of, as well potential prevent, superficial cancers immune‐suppressed although sustained clearance rates are lower than immune‐competent individuals. using a nanoemulsion of ALA daylight or conventional protocol use field cancerization, evidence prevent new SCC remained limited. High‐quality supports strong...
Cold atmospheric plasma (CAP) has been gaining increasing interest as a new approach for the treatment of skin diseases or wounds. Although this demonstrated promising antibacterial activity, its exact mechanism action remains unclear. This study explored in vitro and vivo whether CAP influences gene expression molecular mechanisms keratinocytes. Our results revealed that 2 min using MicroPlaSter ß analogy to performed clinical studies wound induces IL-8, TGF-ß1, TGF-ß2. In assays indicated...
Abstract Numerous comorbidities and cofactors have been known to influence wound healing processes. In this multicentre study, clinical data of 1 000 patients with chronic leg ulcers from ten specialised dermatological care centers were analysed. The patient cohort comprised 567 females 433 males an average age 69·9 years. wounds persisted on for 40·8 months had a mean size 43·7 cm 2 . Venous represented the most common entity accounting 51·3% all wounds, followed by mixed‐type in 12·9%...