A5073412095- Oral and Maxillofacial Pathology
- Reconstructive Surgery and Microvascular Techniques
- Head and Neck Surgical Oncology
- Head and Neck Cancer Studies
- Bone Tumor Diagnosis and Treatments
- Reconstructive Facial Surgery Techniques
- Salivary Gland Tumors Diagnosis and Treatment
- Cancer Diagnosis and Treatment
- Facial Nerve Paralysis Treatment and Research
- Facial Trauma and Fracture Management
- Tumors and Oncological Cases
- Cleft Lip and Palate Research
- Bone health and treatments
- Sarcoma Diagnosis and Treatment
- Oral health in cancer treatment
- Antifungal resistance and susceptibility
- Ear and Head Tumors
- Nerve Injury and Rehabilitation
- Oral and gingival health research
- Sinusitis and nasal conditions
- Vascular Malformations and Hemangiomas
- Bone fractures and treatments
- Teratomas and Epidermoid Cysts
- Oropharyngeal Anatomy and Pathologies
- Head and Neck Anomalies
Yonsei University College of Dentistry
2015-2024
Yonsei University
2015-2024
Yonsei University Health System
2024
Yonsei University Dental Hospital
2016-2020
Kyungpook National University
2017
Severance Hospital
2013
Abstract The Cox proportional hazards model commonly used to evaluate prognostic variables in survival of cancer patients may be too simplistic properly predict a patient’s outcome since it assumes that the is linear combination covariates. In this retrospective study including 255 suitable for analysis who underwent surgical treatment our department from 2000 2017, we applied deep learning-based prediction method oral squamous cell carcinoma (SCC) and validated its performance. Survival...
Patients with odontogenic cysts and tumors may have to undergo serious surgery unless the lesion is properly detected at early stage. The purpose of this study evaluate diagnostic performance real-time object detecting deep convolutional neural network You Only Look Once (YOLO) v2-a learning algorithm that can both detect classify an same time-on panoramic radiographs. In study, 1602 lesions on radiographs taken from 2010 2019 Yonsei University Dental Hospital were selected as a database....
Abstract Background. Artemisinin is of special biological interest because its outstanding antimalarial activity. Recently, it was reported that artemisinin has antitumor Its derivatives, artesunate, arteether, and artemeter, also have activity against melanoma, breast, ovarian, prostate, CNS, renal cancer cell lines. monomer, dimer, trimer derivatives were synthesized from deoxoartemisinin, the dimers trimers found to much more potent than monomers. Methods. We evaluated various...
Tuberculosis is one of the top causes death among curable infectious diseases; it an airborne disease that killed 1.1 million people worldwide in 2010. Anti-tuberculosis drug-induced liver injury primary cause (DILI). Rifampicin most common anti-tuberculosis therapies and has well-known hepatotoxicity. To understand mechanism rifampicin-induced injury, we performed a global proteomic analysis proteins by LC-MS/MS mouse model after oral administration 177 442.5 mg/kg rifampicin (LD10 LD25)...
Abstract It has been demonstrated that development of three-dimensional printing technology supported the researchers and surgeons to apply bone tissue engineering oromandibular reconstruction. In this study, poly caprolactone/beta tricalcium phosphate (PCL/β-TCP) scaffolds were fabricated by multi-head deposition system. The feasibility three-dimensionally (3D) -printed PCL/β-TCP for mandibular reconstruction was examined on critical-sized defect canine mandible. scaffold contained...
It has been recognized that systemic inflammatory markers (SIMs) are associated with patient survival in various types of cancer. This study aimed to determine the optimal cut-off values, and evaluate prognostic performance SIMs for oral squamous cell carcinoma (OSCC) within framework American Joint Committee Cancer (AJCC) cancer staging manual, 8th edition. Records were collected a total 291 patients who had peripheral blood test 1 week prior surgery undergone surgical resection OSCC single...
Although clinical and radiological examinations can be used to diagnose oral cancer, surgical pathology remains the gold standard, these conventional methods have limitations. We evaluated feasibility of longitudinal next-generation sequencing-based liquid biopsy for squamous cell carcinoma surveillance.Eleven patients were enrolled, plasma saliva collected before, 1, 3, 6 months after surgery. Tumor-specific mutations selected using paired, whole-exome analyses tumor tissues whole blood....
Oral squamous cell carcinoma (OSCC) is caused by multiple factors, including carcinogen exposure. Insulin-like growth factor II mRNA-binding protein 3 (IMP3) highly expressed in various cancer cells but rarely normal cells. We investigated whether IMP3 can be used as a prognostic biomarker for OSCC.We performed immunohistochemistry and Western blotting to examine expression human tissues. also correlations among expression, clinicopathologic overall survival.IMP3 was overexpressed OSCC The...
Abstract Purpose The aim of this study was to conduct epidemiologic investigations on the pattern lesion and differences between treatment modalities in terms recurrence by reviewing follow-up records form a basis for planning patient visits. Materials methods In retrospective, single-center cohort study, 266 patients diagnosed with odontogenic keratocyst 1993 2013 were included. Medical radiographic images analyzed age distribution, occurrence site size, modalities, recurrence. Results...
Although the head and neck region is recognized as most common location for peripheral nerve sheath tumors, central involvement, particularly in jaw bones, quite unusual. Neurofibroma one of tumors occurring soft tissue generally appears neurofibromatosis 1 (NF1 or von Recklinghausen's disease). Malignant (MPNSTs) are uncommon sarcomas that almost always arise tissue. Here, we report four cases intraosseous bones compare clinical, radiologic, pathologic findings order to make a differential...
Clear cell odontogenic carcinoma (CCOC) is a rare jaw tumor that was classified as malignant of origin in 2005 by the World Health Organization because its aggressive and destructive growth capacity metastasis to lungs lymph nodes. We report case 66-year-old female who had swelling, incision drainage history well-defined unicystic radiolucent lesion comparable cystic lesion. At first, patient received decompression, size decreased. Three months after cyst enucleation performed. The...
Rhinocerebral mucormycosis (RCM) is an opportunistic, potentially life-threatening fungal disease. This infective disease invades not only the facial sinuses, but also maxilla, zygoma, and rhino-cerebral structures with a massive destruction of skeletons soft tissue. progresses within various underlying diseases, such as diabetes mellitus, hematologic malignancy, renal failure, systemic immunodepression. The relationship between these conditions have been discussed extensively in literature....
Condylar dislocation can arise as a complication in patients who required mandibular and/or condylar reconstruction and were operated on with fibula free flap (FFF) using surgical guides designed simulation surgery. Surgeons should be aware of the complications these present cases when planning performing reconstructions well predicting prognoses. Two showed FFF fixed plate. Three mini-plate. Despite lack clinical symptoms following an FFF, condyle was severely displaced away from glenoid...