A5001411215- HIV Research and Treatment
- HIV/AIDS Research and Interventions
- COVID-19 epidemiological studies
- HIV-related health complications and treatments
- Pneumonia and Respiratory Infections
- COVID-19 Clinical Research Studies
- SARS-CoV-2 and COVID-19 Research
- Long-Term Effects of COVID-19
- COVID-19 and Mental Health
- Respiratory viral infections research
- Antibiotic Use and Resistance
- HIV, Drug Use, Sexual Risk
- Dialysis and Renal Disease Management
- Vaccine Coverage and Hesitancy
- Pharmacological Effects and Toxicity Studies
- Academic Research in Diverse Fields
- Healthcare cost, quality, practices
- COVID-19 Impact on Reproduction
- Acute Lymphoblastic Leukemia research
- Influenza Virus Research Studies
- Central Venous Catheters and Hemodialysis
- Assisted Reproductive Technology and Twin Pregnancy
- Maternal and Perinatal Health Interventions
- Sex work and related issues
- Alkaline Phosphatase Research Studies
Inserm
2017-2024
Centre de recherche en Epidémiologie et Santé des Populations
2017-2024
Université Paris-Saclay
2018-2024
Université de Versailles Saint-Quentin-en-Yvelines
2020-2024
Université Paris-Sud
2017-2018
University College London
2018
Sapienza University of Rome
2018
We aimed to study whether social patterns of exposure SARS-CoV-2 infection changed in France throughout the year 2020, light easing contact restrictions.A population-based cohort individuals aged 15 years or over was randomly selected from national tax register collect socio-economic data, migration history, and living conditions May November 2020. Home self-sampling on dried blood proposed a 10% random subsample all November. A positive anti-SARS-CoV-2 ELISA IgG result against virus spike...
BackgroundInterpretation of the increase in certain inflammatory markers virally suppressed HIV-infected individuals must rely on an appropriate uninfected control group well characterized for non-HIV-related factors that contribute to chronic inflammation, e.g. smoking, alcohol consumption, or being overweight. We compared profiles participants under long-term antiretroviral therapy (ART) with those two HIV-uninfected groups contrasting health behaviours.MethodsWe studied 150 (42 women, 108...
Non-pharmaceutical interventions implemented to block SARS-CoV-2 transmission in early 2020 led global reductions the incidence of invasive pneumococcal disease (IPD). By contrast, most European countries reported an increase antibiotic resistance among Streptococcus pneumoniae isolates from 2019 2020, while increasing number studies stable carriage prevalence over same period. To disentangle impacts COVID-19 pandemic on epidemiology community setting, we propose a mathematical model...
Abstract Introduction In a context of declining condom use and high sexually transmitted infection (STI) incidence, the diffusion “treatment as prevention” (Tasp) more recently pre‐exposure prophylaxis (PrEP) may have changed sexual behaviour newly diagnosed men who sex with (MSM) HIV. Methods Six hundred nine MSM were enrolled followed annually between 2014 2021 in ANRS PRIMO Cohort (ClinicalTrials.gov:NCT03148964) from time HIV seroconversion. We studied changes over calendar before after...
It is unclear how the risk of post-COVID symptoms evolved during pandemic, especially before spread Severe Acute Respiratory Syndrome Coronavirus 2 variants and availability vaccines. We used modified Poisson regressions to compare six-month their associated factors according period first acute COVID: French (March-May 2020) or second (September-November wave. Nonresponse weights multiple imputation were handle missing data. Among participants aged 15 years older in a national...
We aimed to determine the consequences of delayed human immunodeficiency virus type 1 (HIV-1) infection diagnosis by comparing long-term outcomes depending on time combination antiretroviral therapy (cART) initiation in patients diagnosed during primary HIV (PHI).We selected from French National Agency for Research AIDS and Viral Hepatitis (ANRS) PRIMO cohort, treated ≥36 months, with sustained RNA <50 copies/mL: 77 within month following PHI (immediate ART) 73 >12 months after (deferred...
Abstract Introduction Previous studies have reported better immunovirological characteristics in women compared with men after HIV seroconversion. We investigated whether differences persisted under long‐term antiretroviral therapy (ART) individuals treated since acute and early HIV‐1 infection (AHI). Methods Data were obtained for 262 1783 enrolled between 1996 2017 the French multicentre ANRS PRIMO cohort. modelled viral response, immune recovery DNA decay 143 1126 who initiated ART within...
We assessed the impact of early antiretroviral treatment (ART) on human immunodeficiency virus (HIV) antibody detection by rapid tests in 44 individuals after several years successful ART. HIV self-tests and point-of-care were negative 30% 7%-9% cases, respectively. These data reinforce message that patients should never be retested entering care.
Previous studies have reported that polymicrobial peritonitis in peritoneal dialysis (PD) is associated with poor outcomes, but recent data from European cohorts are scarce.We included the French Language Peritoneal Dialysis Registry all patients ≥18 years of age who started PD between January 2014 and November 2020. We compared microbiology patient characteristics mono- peritonitis. assessed outcomes after a first using survival analysis competing events. differentiated microorganisms...
Abstract Background We aimed to study whether social patterns of exposure SARS-CoV-2 infection changed in France throughout the year 2020, light easing contact restrictions. Methods A population-based cohort individuals aged 15 years or over was randomly selected from national tax register collect socio-economic data, migration history, and living conditions May November 2020. Home self-sampling on dried blood proposed a 10% random subsample all November. positive anti-SARS-CoV-2 ELISA IgG...
Abstract We assessed the risk of acquiring severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) from household and community exposure according to age, family ties, socioeconomic living conditions using serological data a nationwide French population-based cohort study, Epidémiologie et Conditions de Vie (EpiCoV) Study. A history SARS-CoV-2 infection was defined by positive anti-SARS-CoV-2 enzyme-linked immunosorbent assay immunoglobulin G result in November–December 2020. applied...
Der Lipopolysaccharid (LPS) – Toll-like Rezeptor-4 (TLR4) Signalweg spielt eine wichtiger Rolle in der Entstehung des Leberversagens. Die rekombinante alkalische Phosphatase (recAP) ist Lage LPS zu deaktivieren. Das Ziel Studie war evaluieren, ob recAP die akuten (ALF) und akut-auf-chronischen Leberversagens (ACLF) verhindert somit potentielle neue Therapieoption darstellt.
To assess changes in the number and profile of utero transfer requests during first lockdown. An observational, retrospective, cohort study. All pregnant women, from Paris area (France), for whom a request to unit was made lockdown France (from 17 March 10 May 2020) or mirror period (years 2016 2019) were included. We compared numbers proportions various indications transfer, rates acceptance proportion outborn deliveries. 206 versus 227, 236, 204 228 2016, 2017, 2018 2019, respectively. The...
Abstract Non-pharmaceutical interventions implemented to block SARS-CoV-2 transmission in early 2020 led global reductions the incidence of invasive pneumococcal disease (IPD). By contrast, most European countries reported an increase antibiotic resistance among Streptococcus pneumoniae isolates from 2019 2020, while increasing number studies stable carriage prevalence over same period. To disentangle impacts COVID-19 pandemic on epidemiology community setting, we propose a mathematical...
ABSTRACT Background Households are specific transmission settings, as they involve close and repeated contacts between individuals of different generations. Household surveys provide a unique opportunity to better understand SARS-CoV-2 the role individual characteristics. Here, we assessed risk acquisition from household community exposure according age, family ties, socioeconomic living conditions using data nationwide population-based EpiCov cohort/ORCHESTRA collaboration in...