With the development of sensor technology, MEMS,wireless communications and wide application wireless sensor, Wireless Sensor Networks have been paid great attention in industry field our daily life. In order to realize agricultural modernization environment protection, this paper designs an monitoring system based on networks, gives hardware design nodes flowchart software. Experiments proved that is low power consumption has stable running high precision, which can remote real-time for...

An efficient and convenient copper-catalyzed chalcogenation of imidazoheterocycles with sulfur/selenium powder coumarinyl triflates has been described. This procedure provides a wide range structurally diverse coumarinylthio-/coumarinylseleno-substituted in good yields functional group tolerance. Biological evaluation showed that the newly synthesized compound 6d possesses significant vitro antiproliferative activities against human-derived esophageal, breast, stomach, prostate cancer cell...

Peptide-based therapeutics hold immense promise for the treatment of various diseases. However, their effectiveness is often hampered by poor cell membrane permeability, hindering targeted intracellular delivery and oral drug development. This study addressed this challenge introducing a novel graph neural network (GNN) framework advanced machine learning algorithms to build predictive models peptide permeability. Our offer systematic evaluation across diverse peptides (natural, modified,...

As a chronic inflammatory disease, rheumatoid arthritis (RA) can cause progressive damage to joints and various organs.

Novel antitumor compounds featuring isoquinoline and indole moieties were synthesized by a silver nitrate promoted domino reaction involving intramolecular cyclization, nucleophilic addition of indole, subsequent N–N bond cleavage. The transformation from readily available starting materials into an interesting class indole-substituted isoquinolines was completed under mild conditions simple operations in moderate to good yields. activity these vitro significantly greater than that reference...

An efficient and convenient copper-catalyzed oxidative chalcogenation of benzothiazoles imidazo[1,2-a]pyridines with sulfur/selenium powder aryl boronic acids was developed. This procedure allows access to a wide range structurally diverse arylchalcogen-substituted benzothiazoles/imidazo[1,2-a]pyridines in good yields functional group tolerance. A biological evaluation revealed that some the obtained products exhibited vitro antiproliferative activities on human-derived lung, stomach,...

The forest is considered as a precious and indispensable nature resource, but fire which can destroy resource safety threaten human-living environment one of the severest disasters. How to monitor collect information at any time, it difficult problem for Forest Fire Prevention Departments urgently solve. With development sensor technology, MEMS wireless communications, network (WSN) has wide application in all kinds fields. In order prevent occurrence, this paper designs monitoring system...

Uncontrolled angiogenesis is a common denominator underlying many deadly and debilitating diseases such as myocardial infarction, chronic wounds, cancer, age-related macular degeneration. As the current range of FDA-approved angiogenesis-based medicines are far from meeting clinical demands, vast reserve natural products traditional Chinese medicine (TCM) offers an alternative source for developing pro-angiogenic or anti-angiogenic modulators. Here, we investigated 100 medicine-derived...

With the improvement of scientific and technological level in China, wireless sensor network technology has been widely promoted applied, which now popularized to various fields society from military defense. Wireless combines technology, communication computer together, ability information collection, transmission processing. In this paper, structure node localization are briefly introduced, key technologies development summarized four aspects energy efficiency, localization, data fusion...

The environment of mine exploitation is special and dangerous, how to real-time monitor collect information on the various nodes, master location miner at any time, it a difficult problem for Coal enterprise urgently solve. This paper describes design monitoring system coal safety constructed by MSP430 nRF905, which has described structure system, working principle, gives hardware sensor nodes flowchart software. used On-line with character simple structure, low cost, power consumption so...

With the rapid development of aerospace and sensing technologies, remote technology various countries all over world has reached a relatively high level. It is an important part machine learning field to apply deep target detection. Based on detection image, this paper analyzes existing algorithms image studies optimal solution based learning.

The forest is considered as a precious and indispensable nature resource, but fire which can destroy resource safety threaten human-living environment one of the severest disasters. How to monitor collect information at any time, it difficult problem for Forest Fire Prevention Departments urgently solve. With development sensor technology, MEMS wireless communications, network (WSN) has wide application in all kinds fields. In order prevent occurrence, this paper designs monitoring system...

According to the grim situation of current global forest and wild land fires, article presents a real-time fire detection system based ZigBee wireless sensor network GPRS network. The gives hardware design node software implementations. nodes are mainly responsible for collecting transporting special environment parameters including temperature, humidity smoke concentrate so on, send data through module remote monitoring center. It has simple structure, low power consumption, flexibility...

Breast cancer is the leading cause of death in women. The current methods chemotherapy for breast generally have strong adverse reactions and drug resistance. Therefore, discovery novel anti-breast lead compounds urgently needed.This study aimed to design synthesize a series 2-alkyl substituted fluorinated genistein analogues evaluate their activity.Target were obtained multistep reaction synthesis. anti-tumor activity I-1~I-35 was evaluated with MCF-7, MDA-MB-231, MDA-MB-435, MCF-10A cell...

With the development of social economy, cultivation Chinese herbal medicine is very common in our country, especially due to modern science and technology information technology, some means used planting process, process precious planting. with help tools, it not only improves artificial herbal, but also greatly scientization planting.This paper designs an intelligent real-time monitoring system medicine, which can monitor environment parameters medicine.

The key technology of the Internet Things is used to conduct intelligent management and control rural agriculture carry out real-time monitoring feedback on various data in agricultural production so as improve farmers' planting efficiency quality, increase income accelerate development economy. Android mobile phones are developing rapidly China, which keep pace with IPhone, accounting for 58% market share smart phones. It will certainly be direction home future apply phone system by...