A5015263586- Transplantation: Methods and Outcomes
- Interstitial Lung Diseases and Idiopathic Pulmonary Fibrosis
- Respiratory viral infections research
- Pneumocystis jirovecii pneumonia detection and treatment
- Cardiac Arrest and Resuscitation
- Renal Transplantation Outcomes and Treatments
- Tracheal and airway disorders
- Cardiovascular and Diving-Related Complications
- Cardiac, Anesthesia and Surgical Outcomes
- Organ Transplantation Techniques and Outcomes
- Mechanical Circulatory Support Devices
- Trauma and Emergency Care Studies
- Maternal and fetal healthcare
- Chronic Obstructive Pulmonary Disease (COPD) Research
- Respiratory Support and Mechanisms
- Prenatal Screening and Diagnostics
- Neonatal Respiratory Health Research
- Pregnancy and preeclampsia studies
- Medical Imaging and Pathology Studies
- Assisted Reproductive Technology and Twin Pregnancy
- Heart Failure Treatment and Management
- Infection Control and Ventilation
- Mobile Health and mHealth Applications
- Digital Radiography and Breast Imaging
- Maternal and Perinatal Health Interventions
University of Toronto
2015-2025
University Health Network
2018-2025
Toronto General Hospital
2019-2025
Biostatistical Consulting (United States)
2025
Health Net
2021-2024
Sheba Medical Center
2024
Toronto Public Health
2023
University of New Brunswick
2023
McMaster University
2023
Society of Interventional Radiology
2022
Sudden cardiac arrest (SCA) is the leading cause of death in athletes during exercise. The effectiveness school-based automated external defibrillator (AED) programmes has not been established through a prospective study.A total 2149 high schools participated observational study beginning 1 August 2009, 31 July 2011. Schools were contacted quarterly and reported all cases SCA. Of these 95% confirmed their participation for entire 2-year period. Cases SCA reviewed to confirm details...
Background Evidence from animal models shows that tissue stiffness increases the invasion and progression of cancers, including mammary cancer. We here use measurements volume projected area compressed breast during mammography to derive estimates examine relationship risk Methods Mammograms were used measure areas total radiologically dense in unaffected breasts 362 women with newly diagnosed cancer (cases) 656 same age who did not have (controls). Measures calculate deformation compression...
Background:There is strong evidence that breast cancer risk influenced by environmental factors. Blood lipid and lipoprotein levels are also factors associated with some We examined whether serial measures of serum lipids lipoproteins were risk.
Human pluripotent stem cell (hPSC)-derived cardiomyocytes (hPSC-CMs) have tremendous promise for application in cardiac regeneration, but their translational potential is limited by an immature phenotype. We hypothesized that large-scale manufacturing of mature hPSC-CMs could be achieved through culture on polydimethylsiloxane (PDMS)-lined roller bottles and the transplantation these cells would mediate better structural functional outcomes than with conventional hPSC-CM populations.We...
To identify which components of maternal vascular malperfusion (MVM) pathology are associated with adverse pregnancy outcomes and to investigate the morphological phenotypes MVM placental their relationship distinct clinical presentations pre-eclampsia and/or fetal growth restriction (FGR).
Heart failure is a common, costly, and debilitating illness. Resynchronization of ventricular contraction in patients with heart improves ejection fraction. The long-term morbidity costs associated such cardiac resynchronization therapy remain unclear.To assess the incremental cost-effectiveness therapy.Markov model Monte Carlo simulation. Future effects were discounted at 3%.Effects data obtained from concurrent systematic review. Health-related quality-of-life cost publicly available or...
Out-of-hospital cardiac arrest is frequent and has poor outcomes. Defibrillation by trained targeted nontraditional responders improves survival versus historical controls, but it unclear whether such defibrillation a good value for the money. Therefore, this study estimated incremental cost effectiveness of in public settings using decision analysis.A Markov model evaluated potential standard emergency medical services (EMS) responders. Standard EMS included first-responder followed...
Percent mammographic density (PMD) is associated with an increased risk of interval breast cancer in screening programs, as are younger age, pre-menopausal status, lower body mass index and hormone therapy. These factors also variations PMD. We have examined whether these variables influence the relative frequency screen-detected cancer, independently or through their associations association tumor size PMD dense non-dense areas cancers.We used data from three case-control studies nested...
BACKGROUND: Residual neuromuscular blockade can be associated with serious postoperative complications. Sugammadex is a newer blocking drug (NMBD) reversal agent that rapidly and completely reverses rocuronium. Whether sugammadex has any advantages over neostigmine in morbidly obese patients obstructive sleep apnea (OSA) unclear. We investigated whether would reduce discharge time from the operating room (OR) compared OSA undergoing bariatric surgery. METHODS: This was prospective,...