A5038631397- Parasites and Host Interactions
- Parasite Biology and Host Interactions
- Helminth infection and control
- Global Maternal and Child Health
- Cholangiocarcinoma and Gallbladder Cancer Studies
- Biological Research and Disease Studies
- Cancer-related molecular mechanisms research
- Trace Elements in Health
- Cancer Genomics and Diagnostics
- Peptidase Inhibition and Analysis
- Aquatic Invertebrate Ecology and Behavior
- Parasitic Infections and Diagnostics
- Metabolomics and Mass Spectrometry Studies
- MicroRNA in disease regulation
- Gut microbiota and health
- Diet and metabolism studies
- Dengue and Mosquito Control Research
- Plant Toxicity and Pharmacological Properties
- Mollusks and Parasites Studies
- Extracellular vesicles in disease
- HIV/AIDS drug development and treatment
- Drug Transport and Resistance Mechanisms
- Aquaculture disease management and microbiota
- Pneumocystis jirovecii pneumonia detection and treatment
- Identification and Quantification in Food
Thammasat University
2014-2024
Hodges University
2022
Khon Kaen University
2011-2014
Australian Institute of Tropical Health and Medicine
2014
James Cook University
2013-2014
Objectives: This study aimed to assess the diagnostic potential of cell-free DNA (cfDNA) and miRNA (cf-miRNA) for distinguishing between Healthy, asymptomatic opisthorchiasis viverrini cholangiocarcinoma in a preliminary manner. Methods: In this study, 36 participants were enrolled into three health status groups: healthy control group (HC), Opisthorchis viverrini-infected (OV), (CCA), each comprising 12 participants. Concentration measurements cfDNA cf-miRNA from plasma conducted....
Opisthorchis viverrini infection is associated with human cholangiocarcinoma and northeast Thailand has the highest incidence of this disease in world. Bithynia siamensis goniomphalos major freshwater snail intermediate host O. area an analysis based on geographical information systems was used to determine effect variation soil surface salt density distribution snail. A malacological survey carried out 56 water bodies Khorat basin, at locations various levels. Mollusk samples were collected...
Freshwater snails in the family Bithyniidae are first intermediate host for Southeast Asian liver fluke (Opisthorchis viverrini), causative agent of opisthorchiasis. Unfortunately, subtle morphological characters that differentiate species this group not easily discerned by non-specialists. This is a serious matter because identification bithyniid fundamental prerequisite better understanding epidemiology disease. Because DNA barcoding, analysis sequence diversity 5' region mitochondrial COI...
Hyperlipidemia is a condition where the blood shows an elevated level of lipid, such as cholesterol and triglyceride. It considered risk factor for all coronary artery death globally. Association microbiome with non-communicable diseases (NCDs) including hyperlipidemia has been reportedly associated. In this study, we hypothesize that change in correlated to serum lipid level, which resulted by increasing dietary fat consumption. The 32 male, 14-week-old, C57BL/6N were divided into 4 groups,...
The snail Bithynia siamensis goniomphalos acts as the first intermediate host for human liver fluke Opisthorchis viverrini, major cause of cholangiocarcinoma (CCA) in Northeast Thailand. undisputed link between CCA and O. viverrini infection has precipitated efforts to understand molecular basis host–parasite interactions with a view ultimately developing new control strategies combat this carcinogenic infection. To date most effort focused on parasite its host, little is known about...
Bithynia siamensis goniomphalos is the snail intermediate host of liver fluke, Opisthorchis viverrini, leading cause cholangiocarcinoma (CCA) in Greater Mekong sub-region Thailand. Despite severe public health impact Opisthorchis-induced CCA, knowledge molecular interactions occurring between parasite and its scant. The examination differences gene expression profiling uninfected O. viverrini-infected B. could provide clues on fundamental pathways involved regulation snail-parasite...
This study aimed to identify the recent risk factors for Opisthorchis viverrini infection and cholangiocarcinoma (CCA) improve disease prevention. The participants were divided into following 3 groups based on their health status: healthy control (nonOV nonCCA), those with O. (OV), CCA. A questionnaire was used explore lifestyle behaviors. Multivariate logistic regression backward elimination significant factors. results showed that both CCA age>50 years (odd ratio (OR)=8.44, P<0.001, 95%...
The human liver fluke Opisthorchis viverrini (Platyhelminthes, Trematoda, Digenea) uses snails of the genus Bithynia as first intermediate host. Peculiarly among trematodes, eggs O. hatch within digestive tract its snail It remains uncertain whether hatching in this species is mediated through mechanical fracture eggshell or by digestion with specific enzymes. This study aimed to characterize enzymes inhibitors and factors involved activity eggs. For measuring egg vivo, 50 mature were fed...
Bithynia funiculata is the first intermediate host of human liver fluke Opisthorchis viverrini in northern Thailand but its identification through morphological analysis often problematic due to shortage gastropod taxonomists. As a consequence, we focused on development species-specific primers for use as an tool. Our work involved recovery 502-base pair (bp) amplicon unknown function whose effectiveness was tested by analyzing specimens B. from 3 locations Thailand. This primer set did not...
Hyperlipidemia is a risk factor for cardiovascular diseases. This study aimed at investigating the effects of consuming omega-3-rich pork lard on serum lipid profile and gut microbiome mice model. We divided 23 C57BL/6NJ males (16-week-old) into 3 groups, each group received either control diet, high-fat diet coconut oil (coconut oil), or (omega lard) 28 days. Thereafter, fasting lipids fecal microbiomes were analyzed. The cholesterol, triglyceride, LDL levels omega lard-treated...
Abstract Research on the effects of environmental factors influenced by climate change parasite transmissibility is an area garnering recent attention worldwide. However, there still a lack studies life cycle Opisthorchis viverrini , carcinogenic trematode found in countries Lower Mekong subregion Lao PDR, Cambodia, Myanmar, Vietnam and Thailand. To evaluate influences water temperature salinity liver fluke O. through cercarial stage, longevity cercaria was examined at different experimental...
The snail Bithynia siamensis goniomphalos acts as the first intermediate host for human liver fluke Opisthorchis viverrini, major cause of cholangiocarcinoma (CCA) in Northeast Thailand. This data article contains results obtained from analysis proteins differentially expressed B. upon infection with O. viverrini. It generated iQuantitator software including a pdf each sample protein׳s relative expression summary and per-protein detailed all time points studied an excel file containing raw...
Abstract The human liver fluke Opisthorchis viverrini ( Ov ), the primary risk factor for cholangiocarcinoma (CHCA), is a parasite endemic to southeast Asian countries. With no effective treatments CHCA currently available, early diagnosis and treatment of infection remains only practical method prevention CHCA. In this study, plasma phosphoproteomes patients in non- infection, non-cholangiocarcinoma subject group (non-OVCCA), asymptomatic infected (OV), (CCA), were investigated identify...